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Engineering Commons

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Biomedical Engineering and Bioengineering

Theses/Dissertations

2011

Magnetic resonance imaging

Articles 1 - 3 of 3

Full-Text Articles in Engineering

Incorporating The Aortic Valve Into Computational Fluid Dynamics Models Using Phase-Contrast Mri And Valve Tracking, David C. Wendell Oct 2011

Incorporating The Aortic Valve Into Computational Fluid Dynamics Models Using Phase-Contrast Mri And Valve Tracking, David C. Wendell

Dissertations (1934 -)

The American Heart Association states about 2% of the general population have a bicuspid aortic valve (BAV). BAVs exist in 80% of patients with aortic coarctation (CoA) and likely influences flow patterns that contribute to long-term morbidity post-surgically. BAV patients tend to have larger ascending aortic diameters, increased risk of aneurysm formation, and require surgical intervention earlier than patients with a normal aortic valve. Magnetic resonance imaging (MRI) has been used clinically to assess aortic arch morphology and blood flow in these patients. These MRI data have been used in computational fluid dynamics (CFD) studies to investigate potential adverse hemodynamics …


Comparison Of Progression Of Diffuse Axonal Injury With Histology And Diffusion Tensor Imaging, Nisrine Zakaria Jan 2011

Comparison Of Progression Of Diffuse Axonal Injury With Histology And Diffusion Tensor Imaging, Nisrine Zakaria

Wayne State University Dissertations

Diffuse axonal injury, also known as traumatic axonal injury (TAI), is a major contributor to the pathology of traumatic brain injury. However, TAI is undetectable to conventional clinical magnetic resonance (MR) imaging techniques. Histologically, TAI is characterized by swollen axons that eventually disconnect and form axonal retraction balls (RB) in various white matter tracts. MR-diffusion tensor imaging (MR-DTI) has been reported to be sensitive to TAI in human TBI patients by measuring water molecular diffusion motion in white matter fiber tracts. To date, only one correlative animal study has been carried out to investigate the DTI relationship to TAI, and …


A Left Ventricular Motion Phantom For Cardiac Magnetic Resonance Imaging, Mehmet Ersoy Jan 2011

A Left Ventricular Motion Phantom For Cardiac Magnetic Resonance Imaging, Mehmet Ersoy

ETD Archive

The mammalian left ventricle (LV) has two distinct motion patterns: wall thickening and rotation. The purpose of this study was to design and build a low-cost, non-ferromagnetic LV motion phantom, for use with cardiac magnetic resonance imaging (MRI), that is able to produce physiologically realistic LV wall thickening and rotation. Cardiac MRI is continuously expanding its range of techniques with new pulse sequences, including new tissue tagging techniques which allow intra-myocardial deformation to be visualized. An essential step in the development of new cardiac MRI techniques is validating their performance in the presence of motion. MRI-compatible dynamic motion phantoms are …