Engineering Commons^™

Advantages Of Air Cooling In Thermal Ablation, Alexander Sheikh

Kansas State University Undergraduate Research Conference

Advantages of Air Cooling in Thermal Ablation

Alex Sheikh, Dr. Punit Prakash, Hojjat Fallahi

Department of Electrical and computer Engineering

Thermal ablation is the method of destroying tumors through the application of extreme temperatures. For this experiment, heat is used and supplied by an amplifier/power generator. The heat is transported out through a catheter device and into the designated area of the tumor. Cooling the tip of the device can be used to control this heat in effort to expand the ablation size and cut down on the destruction of unwanted tissue. Thus far, water has been the primary strategy …

Establishment Of 3-D Human Colorectal Cancer Spheroids, India Barnett

Kansas State University Undergraduate Research Conference

Three-Dimensional (3D) cell culture plays an important role in cancer biology by providing a life-like microenvironment as a model for drug discovery and treatment. Hydrogels, like many other 3D scaffolds, demonstrate a unique property as matrices for 3D cell culture. The goal of this project is to establish a 3D cell culture for colorectal cancer and apply this 3D model to drug testing. Colorectal cancer is one of the most common cancers in the United States with an early detection rate of 39%. Previously, 2D cell culture of human colorectal cancer cells, SW480, was used to determine the efficacy of …