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Articles 1 - 6 of 6
Full-Text Articles in Engineering
Verification Of Proton Range Predictions In Proton Treatment Planning Using X-Ray Ct Or Proton Ct Imaging, Nicholas S. Yee
Verification Of Proton Range Predictions In Proton Treatment Planning Using X-Ray Ct Or Proton Ct Imaging, Nicholas S. Yee
Graduate Research Theses & Dissertations
The objective of this paper is to compare the range errors for two treatment plans; one using x-ray CT and the other using proton CT for calculating dose distributions in an animal tissue phantom. We shot 150 MeV proton beam through a meat phantom to a film stack to measure the exponential drop of dose at the Bragg peak until zero dose remained. Plotting the depth dose curves and performing gamma analyses are two ways to quantify the proton range errors when comparing them to depth dose curves from film measurements in the phantom. The depth dose curves give us …
Experimental Evaluation Of Micro-Epidermal Actuators On Flexible Substrates, Courtney D. Bradley
Experimental Evaluation Of Micro-Epidermal Actuators On Flexible Substrates, Courtney D. Bradley
Graduate Research Theses & Dissertations
Does embedding actuators in a flexible substrate increase their performance in hearing aids? What are the differences in damping experienced by actuators of different diameters and at different locations? At what frequency is peak acceleration achieved and what role does the size of the actuator and embedding it in a flexible substrate play? These questions will form the basis of this thesis. This work was done to develop a small non-invasive Band-Aid-©-like hearing aid. The novelty of this device requires a detailed analysis of piezoelectric actuators. This is a continuation of past students’ work on the topic. The main parameters …
Barcode Biosensors Based On Surface Plasmon Resonance, Sneha Ramesh
Barcode Biosensors Based On Surface Plasmon Resonance, Sneha Ramesh
Graduate Research Theses & Dissertations
Affordable and easy to use biological assays are the current need of the day owing to the rising cost of health care within the US and worldwide. The goal of this thesis is to develop a sensitive label-free biosensing scheme exploiting surface plasmon resonance (SPR) that yields the sensor output in an easy-to-read optical bio-barcode format for high through put and multiplexed medical diagnostics. Through this research, we would like to investigate if SPR phenomena can be achieved by fabricating SP supporting metallic structures over a nanoporous dielectric layer whose optical constants are progressively varied across the substrate in a …
Clinical Applications And Feasibility Of Proton Ct And Proton Radiography, Christina Marie Sarosiek
Clinical Applications And Feasibility Of Proton Ct And Proton Radiography, Christina Marie Sarosiek
Graduate Research Theses & Dissertations
Proton therapy is a form of radiation treatment for cancer that utilizes the Bragg peak to create conformal high dose regions around the tumor volume. However, the use of x-ray computed tomography (CT) and x-ray radiography for treatment planning and pre-treatment quality assurance procedures improves the achievable effectiveness of proton treatment plans (using proton CT) and the pretreatment verification (using proton radiography). Errors in the conversion from x-ray Hounsfield units (HU) to proton relative stopping powers (RSP) leads to errors in the predicted proton range. To account for the errors, 3.5% margins are included in the treatment plan. This means …
Physical And Mechanical Properteis Of Magnesium-Incorporated Bone Substitute Materials, Sarah E. Fleck
Physical And Mechanical Properteis Of Magnesium-Incorporated Bone Substitute Materials, Sarah E. Fleck
Graduate Research Theses & Dissertations
Calcium phosphate (CaP) ceramics have become popular as bone substitutes due to their biocompatibility and similarity to natural bone. Although they are widely used, the mechanical and biological properties of these CaP ceramics can be improved by various methods such as combining them with polymers or ionic substitution in their crystal structure. In current research, we have used carboxymethyl cellulose (CMC) and magnesium (Mg) to modify the physical and mechanical properties of CaP. CMC is a derivative of cellulose which is hydrophilic, biodegradable, and biocompatible. Presence of Mg, a trace element naturally found in the body, is linked to bone …
Surface Modification Of Titanium For Orthopedic And Drug Delivery Applications, Prantik Roy Chowdhury
Surface Modification Of Titanium For Orthopedic And Drug Delivery Applications, Prantik Roy Chowdhury
Graduate Research Theses & Dissertations
Titanium is one of the most attractive metal used in orthopedic and drug delivery applications because of its excellent mechanical properties, biocompatibility and high corrosion resistance. However, due to its bio-inertness, fibrous tissue forms between the bone and implant which causes loosening of implant. Surface modification can play an important role to enhance interaction between implant and the surrounding tissues which reduces the implant failure. The aim of this study is to a) incorporate magnesium (Mg) into modified titanium surface by different deposition methods for bone-implant interaction, b) modify the surface of titanium by alkali treatment, and c) investigate the …