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Biomedical Engineering and Bioengineering

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Cerebellum

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Sensorimotor Content Of Multi-Unit Activity In The Paramedian Lobule Of The Cerebellum, Esma Cetinkaya Aug 2022

Sensorimotor Content Of Multi-Unit Activity In The Paramedian Lobule Of The Cerebellum, Esma Cetinkaya

Dissertations

Based on Center for Disease Control and Prevention report 2016, around 39.5 million people in the United States suffer from motor disabilities. These disabilities are due to traumatic conditions like traumatic brain injury (TBI), neurological diseases such as amyotrophic lateral sclerosis (ALS), or congenital conditions. One of the approaches for restoring the lost motor function is to extract the volitional information from the central nervous system (CNS) and control a mechanical device that can replace the function of a paralyzed limb through systems called Brain-Computer Interfaces (BCI).

One of the major challenges being faced in BCIs and also in general …


High Frequency Field Potentials Of The Cerebellar Cortex, Jonathan David Groth May 2015

High Frequency Field Potentials Of The Cerebellar Cortex, Jonathan David Groth

Dissertations

The cerebellum plays a crucial role in motor coordination along with basal ganglia and the motor areas of the cerebral cortex. Both somatosensory and the cerebro-cerebral pathways bring in massive amounts of neural information to the cerebellum. The output of the cerebellar cortex projects to various motor cortices as well as down to the spinal cord to make its contributions to the motor function.

The origin and function of the field potential oscillations in the cerebellum, especially in the high frequencies, have not been explored sufficiently. The primary objective of this study was to investigate the spatio-temporal characteristics of high …