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Biomedical Engineering and Bioengineering
Backscattered electron imaging; microradiography; projection effect errors; histometry; mineral content
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Full-Text Articles in Engineering
Projection Effect Errors In Biomaterials And Bone Research, K. N. Bachus, R. D. Bloebaum
Projection Effect Errors In Biomaterials And Bone Research, K. N. Bachus, R. D. Bloebaum
Cells and Materials
Micoradiography and backscattered electron (BSE) imaging are techniques used to investigate the morphologic, histometric, and mineral content changes at the bone/biomaterials interface. Investigators have shown that the superimposition of multiple tissue layers can cause errors with both the morphologic observations and the histometric measurements of bone. The objective of this study was to document errors in the bone mineral content measurements associated with overlapping tissues.
Using a digital image analysis system, microradiographic and BSE images from canine cortical and cancellous bone were captured and analyzed. The results of this study showed that microradiography had more projection effect errors associated with …