Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Engineering
Optimal Hemoglobin Extinction Coefficient Data Set For Near-Infrared Spectroscopy, Yue Zhao, Lina Qiu, Yunlong Sun, Chong Huang, Ting Li
Optimal Hemoglobin Extinction Coefficient Data Set For Near-Infrared Spectroscopy, Yue Zhao, Lina Qiu, Yunlong Sun, Chong Huang, Ting Li
Biomedical Engineering Faculty Publications
Extinction coefficient (ε) is a critical parameter for quantification of oxy-, deoxy-, and total-hemoglobin concentrations (Δ[HbO2], Δ[Hb], Δ[tHb]) from optical measurements of Near-infrared spectroscopy (NIRS). There are several different ε data sets which were frequently used in NIRS quantification. A previous study reported that even a small variation in ε could cause a significant difference in hemodynamic measurements. Apparently the selection of an optimal ε data set is important for NIRS. We conducted oxygen-state-varied and blood-concentration-varied model experiments with 57 human blood samples to mimic tissue hemodynamic variations. Seven reported ε data sets were evaluated by comparisons between …
A Brief Review Of Opt101 Sensor Application In Near-Infrared Spectroscopy Instrumentation For Intensive Care Unit Clinics, Ting Li, Fulin Zhong, Boan Pan, Zebin Li, Chong Huang, Zishan Deng
A Brief Review Of Opt101 Sensor Application In Near-Infrared Spectroscopy Instrumentation For Intensive Care Unit Clinics, Ting Li, Fulin Zhong, Boan Pan, Zebin Li, Chong Huang, Zishan Deng
Biomedical Engineering Faculty Publications
The optoelectronic sensor OPT101 have merits in advanced optoelectronic response characteristics at wavelength range for medical near-infrared spectroscopy and small-size chip design with build-in trans-impedance amplifier. Our lab is devoted to developing a series of portable near-infrared spectroscopy (NIRS) devices embedded with OPT101 for applications in intensive care unit clinics, based on NIRS principle. Here we review the characteristics and advantages of OPT101 relative to clinical NIRS instrumentation, and the most recent achievements, including early-diagnosis and therapeutic effect evaluation of thrombus, noninvasive monitoring of patients' shock severity, and fatigue evaluation. The future prospect on OPT101 improvements in noninvasive clinical applications …