Engineering Commons^™

Machine Learning Offers Predictive Insight Into The Silver Nanomaterial Protein Corona, Matthew Findlay

Bioengineering Senior Theses

The use of engineered nanomaterials (ENMs) in consumer and commercial products is increasing rapidly. The small size and high surface reactivity of ENMs gives them a range of attractive properties, and allows them to be incorporated into various materials. These properties make ENMs very appealing to modern industry, but also make ENMs toxic, causing serious health and environmental concerns. This toxicity is largely driven by the formation of a protein corona on the surface of ENMs. This protein corona is caused by proteins encountered in biological systems that bind to the surface of (ENMs). Despite the importance of the protein …