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Biomedical Engineering and Bioengineering

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2008

Cell Printing

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Human Microvasculature Fabrication Using Thermal Inkjet Printing Technology, Xiaofeng Cui Dec 2008

Human Microvasculature Fabrication Using Thermal Inkjet Printing Technology, Xiaofeng Cui

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The current tissue engineering paradigm is that successfully engineered thick tissues must include vasculature. As biological approaches alone such as VGEF have fallen short of their promises, one may look for an engineering approach to build microvasculature. With the advent of cell printing, one may be able to build precise human microvasculature with suitable bio-ink. Human Microvascular Endothelial Cells (HMVEC) and fibrin were studied as bio-ink for microvasculature construction. Endothelial cells are the only cells to compose the human capillaries and also the major cells of blood vessel intima layer. Fibrin has been already widely recognized as tissue engineering scaffold …