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Full-Text Articles in Engineering
Towards Patient Specific Mitral Valve Modelling Via Dynamic 3d Transesophageal Echocardiography, Patrick Carnahan
Towards Patient Specific Mitral Valve Modelling Via Dynamic 3d Transesophageal Echocardiography, Patrick Carnahan
Electronic Thesis and Dissertation Repository
Mitral valve disease is a common pathologic problem occurring increasingly in an aging population, and many patients suffering from mitral valve disease require surgical intervention. Planning an interventional approach from diagnostic imaging alone remains a significant clinical challenge. Transesophageal echocardiography (TEE) is the primary imaging modality used diagnostically, it has limitations in image quality and field-of-view. Recently, developments have been made towards modelling patient-specific deformable mitral valves from TEE imaging, however, a major barrier to producing accurate valve models is the need to derive the leaflet geometry through segmentation of diagnostic TEE imaging. This work explores the development of volume …
Mitral Valve Imaging And Biomechanics: A Workflow Towards Computational Modeling And Validation, Sam Stephens
Mitral Valve Imaging And Biomechanics: A Workflow Towards Computational Modeling And Validation, Sam Stephens
Graduate Theses and Dissertations
The mitral valve serves a critical role in healthy cardiac function by ensuring the unidirectional flow of oxygenated blood from the left atrium into the left ventricle. It experiences the highest pressures found within the heart and its closure is the result of a complex interaction of several different structures that, furthermore, are unique to each individual. Despite the valve’s vital role however, the specific function of these constituent structures is not fully understood. This, confounded by its asymmetric, personalized nature, make surgical interventions for the mitral valve far less effective than for its neighboring aortic valve. Efforts to overcome …