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Full-Text Articles in Engineering
Scanning Electron Microscopy Of The Osteoclast-Bone Interface In Vivo, H. Zhou, R. Chernecky, J. E. Davies
Scanning Electron Microscopy Of The Osteoclast-Bone Interface In Vivo, H. Zhou, R. Chernecky, J. E. Davies
Cells and Materials
Rat femoral bones were studied by scanning electron microscopy to demonstrate the morphology of osteoclast- bone matrix interfacial relationships. Two general morphological types of actively resorbing osteoclasts were observed . One cell type was approximately ovoid with highly fimbriated borders, fully attached and closely adapted to the resorption surface. The ruffled border of such cells was composed of a number of individual filopodia which were of uniform , regular shape and approximately 2-3 μm in length and 150 nm in diameter. They were found to penetrate the bone matrix to a depth of 1 μm and interdigitated with the surrounding …
Ultrastructural, Cytochemical, And Immunocytochemical Studies On Bone And Its Interfaces, M. D. Mckee, A. Nanci
Ultrastructural, Cytochemical, And Immunocytochemical Studies On Bone And Its Interfaces, M. D. Mckee, A. Nanci
Cells and Materials
Bone cells possess the ability to synthesize, secrete and direct the assembly and maintenance of extracellular matrix to form a functionally rigid and/or weight-bearing mineralized tissue complex, the skeleton. The skeleton not only supports and protects the organs and tissues of the body, but also acts as a mineral ion reservoir for maintaining systemic calcium balance (calcium homeostasis). The remarkable biological precision necessary for the formation, turnover and constant adaptation of bone to external mechanical forces is a dynamic process requiring a coordinated cellular effort relying on a variety of cell-cell and cell-matrix/mineral interactions. Indeed, cell-matrix interfaces found in a …
Cell-Degradation Of Calcium Phosphate Ceramics, P. Frayssinet, N. Rouquet, F. Tourenne, J. Fages, D. Hardy, G. Bonel
Cell-Degradation Of Calcium Phosphate Ceramics, P. Frayssinet, N. Rouquet, F. Tourenne, J. Fages, D. Hardy, G. Bonel
Cells and Materials
Calcium phosphate ceramics are used in bone surgery under different forms: dense or porous ceramic s as bone substitute, thin ceramic coatings on metallic implants as an osseointegration enhancer. Their degradation depends on their physico-chemical properties and particularly on their chemical composition. Natural calcium phosphates of bone are degraded by mononuclear or multinuclear cells and the extracellular matrix induces the differentiation of the degrading-cells. Hydroxyapatite, which is one of the most used calcium phosphates , is known as a low degradation material. However, the histological analysis of implanted HA-materials both in animals and in humans showed that a cellular degradation …