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Fully Coupled Fluid Structure Interaction Simulation Of Bioprosthetic Heart Valves: A Numerical And Experimental Analysis, Masod Sadipour

Electronic Theses and Dissertations

Aortic stenosis impacts approximately 7% of the global population. In the past decade, the role of computational modeling has been becoming considerably important in the design of BHVs. To obtain reliable solutions in computational modeling, it is essential to consider accurate properties of bioprosthetic heart valves (BHVs), such as density and mechanical properties. Previous computational studies assumed (bovine pericardium) BP used in BHVs density was comparable to water or blood. Yet, BP is subjected to multiple treatments like fixation and anti-calcification. In Chapter 2, I measured BP density and its effect on BHV leaflet stress and strain. In the second …