Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Engineering
Controlling Dimensionality In A Systems Approach To Dynamic Multimodal Functional Brain Imaging, Srinivas Laxminarayan, Manu Ben Jonny, Solomon Diamond, Dana Brooks, Gilead Tadmore, Eric Miller, David Boas
Controlling Dimensionality In A Systems Approach To Dynamic Multimodal Functional Brain Imaging, Srinivas Laxminarayan, Manu Ben Jonny, Solomon Diamond, Dana Brooks, Gilead Tadmore, Eric Miller, David Boas
Dana Brooks
The complementary spatial, temporal and specificity advantages of MRI, EEG, MEG, PET and DOT for functional brain imaging motivate interest in multimodal functional brain imaging. State-variable dynamical systems modeling of neural activity and its relation to local hemodynamics further coupled with autonomic physiology offers enhanced spatiotemporal resolution and insight into physiological signals and mechanisms. However, such a model also implies an explosion of state dimension. We discuss strategies for controlling this high dimensionality based on subspace approaches applied to the observed data and the model structure, and also describe some implications for understanding human brain function.
Hemodynamically Constrained Dynamic Diffuse Optical Tomography Under Mammographic Compression, Eleonora Vidolova, Dana H. Brooks, Eric L. Miller, Stefan Carp, David A. Boas
Hemodynamically Constrained Dynamic Diffuse Optical Tomography Under Mammographic Compression, Eleonora Vidolova, Dana H. Brooks, Eric L. Miller, Stefan Carp, David A. Boas
Dana Brooks
This poster considers these points: DOT taken along x-ray mammogram provide valuable functional information, X-ray mammography only gives structural information hard to distinguish between benign and malignant masses, Oxygen consumption (OC) and blood flow (F) contrasts observed between malignant and normal tissue[3, 4], Blood flow, oxygen saturation(SO2), water and lipid distributions could specify the degree of malignancy of a tumor, Physiological changes in the breast due to mammographic compression are significant and should be taken into account[2].