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Ultra-High Field Mri Methods For Precise Anatomical And Spectroscopic Measurements In The Brain And Application To Neurological And Neuropsychiatric Diseases, Judy Alper
Dissertations and Theses
Neurological and neuropsychiatric diseases and disorders are a major burden on society, impairing the health and functioning of millions of people every year. There is a need to define the biological bases of these diseases and identify potential biomarkers to improve diagnosis, monitoring, and treatment efficacy across multiple diseases.
Magnetic resonance imaging (MRI) is a noninvasive imaging technique which facilitates detection of brain lesions and visualization of the brain overall. However, limitations in contrast and resolution at clinical field strengths may hinder investigation of the underlying biological mechanisms of these diseases. Ultra-high field MRI scanners, such as those at 7-Tesla, …