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Engineering Commons

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Biomedical

University of Louisville

Electronic Theses and Dissertations

2019

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Automatic Signal And Image-Based Assessments Of Spinal Cord Injury And Treatments., Samineh Mesbah May 2019

Automatic Signal And Image-Based Assessments Of Spinal Cord Injury And Treatments., Samineh Mesbah

Electronic Theses and Dissertations

Spinal cord injury (SCI) is one of the most common sources of motor disabilities in humans that often deeply impact the quality of life in individuals with severe and chronic SCI. In this dissertation, we have developed advanced engineering tools to address three distinct problems that researchers, clinicians and patients are facing in SCI research. Particularly, we have proposed a fully automated stochastic framework to quantify the effects of SCI on muscle size and adipose tissue distribution in skeletal muscles by volumetric segmentation of 3-D MRI scans in individuals with chronic SCI as well as non-disabled individuals. We also developed …