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Articles 1 - 5 of 5
Full-Text Articles in Engineering
Compositional Optimization Of Amyloid-Graphene Oxide Nanohybrids For Biomaterials, Claire L. Drewery
Compositional Optimization Of Amyloid-Graphene Oxide Nanohybrids For Biomaterials, Claire L. Drewery
Materials Engineering
Amyloid nanofibrils are natural materials capable of self-assembling into precise structures with tunable functionalities, while exhibiting excellent mechanical properties. In combination with highly conductive graphene oxide (GO), the 1-D amyloid nanofibrils and 2-D nanosheets of GO can produce a robust and bio-functional nanohybrid, hypothesized to exhibit multi-domain functional properties useful for enzyme sensing, water purification, drug delivery, and tissue scaffolding applications. Here, we examine the properties of an amyloid-graphene oxide nanohybrid film made with amyloids derived from hen egg white lysozymes in an attempt to explore the diverse toolbox of amyloid derivatives and establish ideal fabrication methods and formulations of …
Analysis Of The Low-Cycle Fatigue Behavior Of Silicone Rubber For Biomedical Balloons, Chase Cooper
Analysis Of The Low-Cycle Fatigue Behavior Of Silicone Rubber For Biomedical Balloons, Chase Cooper
Materials Engineering
The development of a medical drug delivery device that allows for the deployment drugs into the adventitial tissue of blood vessels requires the inflation of a silicone elastomer. The inflated silicone must be able to consistently endure multiple loading cycles without failing so that the device can operate reliably. There are multiple methods of processing the silicone for the device and the goal of this study is to examine the effect of the various processing methods on the characteristics of the silicone. The Dynamic Mechanical Analysis Machine (DMA) is used to model the conditions of the device’s application by performing …
Molecular Dynamics Investigation Of The Arabinan-Cellulose Interface For Cellulose Nanocomposite Applications, Luke Thornley
Molecular Dynamics Investigation Of The Arabinan-Cellulose Interface For Cellulose Nanocomposite Applications, Luke Thornley
Materials Engineering
Atom level computer simulations of the arabinan and cellulose interface were performed to better understand the mechanisms that give arabinan-cellulose composites (ArCCs) their strength with the goal to improve man-made ArCCs. The molecular dynamics (MD) software LAMMPS was used in conjunction with the ReaxFF/c force field to model the bond between cellulose and arabinan. A cellulose nanocrystal with dimensions 51 x 32 x 8 Å was minimized with various weight percent of water, 0%, 3%, 5%, 8%, 10%, and 12%. After the system was equilibrated for at least 100,000 femtoseconds, an arabinan molecule composed of 8 arabinose rings was added …
Fluorescence Characterization Of Quantum Dots For Use As Biomarkers, Logan M. Grimes
Fluorescence Characterization Of Quantum Dots For Use As Biomarkers, Logan M. Grimes
Materials Engineering
Fluorescence profiles of quantum dots (QDs) were characterized to select the ideal QDs for encapsulation in phospholipids for use as biomarkers to selectively adhere to cancer cells. QDs were synthesized and extracted 0, 30, 60, and 90 seconds after precursor compounds were mixed. These extractions were isolated by extraction time. Portions from each vial were coated in a zinc sulfide shelling procedure, leaving at least half of the QD solution unshelled. These samples were characterized over four days to monitor fluctuations in fluorescence. This was done utilizing an Ocean Optics spectrometer in conjunction with Spectra Suite software. The central wavelength, …
Corrosion Of Stainless Steel 316l And Astm F75 Cobalt Chromium Alloy During Immersion Testing In Silver Salt Solutions, Meagan Higgins
Corrosion Of Stainless Steel 316l And Astm F75 Cobalt Chromium Alloy During Immersion Testing In Silver Salt Solutions, Meagan Higgins
Materials Engineering
This study evaluates the potential effects of silver salts on biocompatible metals used for prostheses during the chemical reduction process to produce a silver antimicrobial layer on the metal’s surface. Samples of two biocompatible metals were obtained: Stainless Steel 316L and ASTM F75 Cobalt Chromium Alloy. Three different silver salts were also acquired: silver nitrate, silver sulfadiazine, and silver chloride. Specimens of each metal were cut to size using a 4-1/2 inch aluminum oxide, 40 grit, cut off wheel for metal, attached to a Dewalt Angle Grinder. The biocompatible metal samples were then subject to either Solution 1, water with …