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Apply Dry Powder On Drug Loading And Enteric Coating Of Esomeprazole Magnesium Trihydrate Beads And Capsules, Xiaojing Ge
Apply Dry Powder On Drug Loading And Enteric Coating Of Esomeprazole Magnesium Trihydrate Beads And Capsules, Xiaojing Ge
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Esomeprazole magnesium tri-hydrate (EMT) is a proton pump inhibitor, used for the treatment of gastric and duodenum ulcers. It is currently the best choice for the treatment of acid-related diseases, but it is extremely unstable in gastric acid and sensitive to wet, heat, light. It also will react with the enteric coating material used in this study. So enteric coating and sub coating is needed.
This study offers a new approach, dry powder coating technology, to achieve drug loading and enteric coating of EMT beads and capsules. Dry powder coating, a new type of solvent-less coating technology, can address most …