Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Engineering

Rapid Biocompatibility Analysis Of Materials Via In Vivo Fluorescence Imaging Of Mouse Models, Kaitlin M. Bratlie, Tram T. Dang, Stephen Lyle, Matthias Nahrendorf, Ralph Weissleder, Robert Langer, Daniel G. Anderson Apr 2010

Rapid Biocompatibility Analysis Of Materials Via In Vivo Fluorescence Imaging Of Mouse Models, Kaitlin M. Bratlie, Tram T. Dang, Stephen Lyle, Matthias Nahrendorf, Ralph Weissleder, Robert Langer, Daniel G. Anderson

Kaitlin M. Bratlie

Background: Many materials are unsuitable for medical use because of poor biocompatibility. Recently, advances in the high throughput synthesis of biomaterials has significantly increased the number of potential biomaterials, however current biocompatibility analysis methods are slow and require histological analysis. Methodology/Principal Findings: Here we develop rapid, non-invasive methods for in vivo quantification of the inflammatory response to implanted biomaterials. Materials were placed subcutaneously in an array format and monitored for host responses as per ISO 10993-6: 2001. Host cell activity in response to these materials was imaged kinetically, in vivo using fluorescent whole animal imaging. Data captured using whole animal …


Antimicrobial And Antioxidant Activities Of Essential Oil And Methanol Extract Of Jasminum Sambac From Djibouti, Fatou Abdoul-Latif, Prosper Edou, François Eba, Nabil Mohamed, Adwa Ali, Samatar Djama, Louis-Clément Obame, Mamoudou Hama Dicko Mar 2010

Antimicrobial And Antioxidant Activities Of Essential Oil And Methanol Extract Of Jasminum Sambac From Djibouti, Fatou Abdoul-Latif, Prosper Edou, François Eba, Nabil Mohamed, Adwa Ali, Samatar Djama, Louis-Clément Obame, Mamoudou Hama Dicko

Pr. Mamoudou H. DICKO, PhD

The essential oil of jasminum sambac from Djibouti was subjected to screening for their possible antioxidant activity by two complementary test systems, namely DPPH free radical scavenging and beta-carotene-linoleic acid assays. Butylated hydroxytoluene (BHT) was used as positive control in both test systems. In the DPPH test system, the IC50 value of essential oil and methanol extract were respectively 7.43 and 2.30 μg/ml. In the beta-carotene-linoleic acid system, oxidation was effectively inhibited by Jasminum sambac, the RAA value of essential oil and methanol extract were respectively 96.6 and 93.9%. When compared to BHT, the essential oil and methanol extract had …


Anhang: Auszüge Aus Dem Späteren Leben Von Professor Dr. Otto Vogl, Otto Vogl Jan 2010

Anhang: Auszüge Aus Dem Späteren Leben Von Professor Dr. Otto Vogl, Otto Vogl

Otto Vogl

No abstract provided.