Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Engineering

Detection Of Foodborne Pathogens By Micro-Filtration Using A Continuous Cell Concentrator Device, Klaire E. Jeffries, Eduardo Ximenes, Michael R. Ladisch Oct 2013

Detection Of Foodborne Pathogens By Micro-Filtration Using A Continuous Cell Concentrator Device, Klaire E. Jeffries, Eduardo Ximenes, Michael R. Ladisch

The Summer Undergraduate Research Fellowship (SURF) Symposium

Protecting consumers from foodborne illness is an important health concern facing the food industry today. An important deficiency exposed by foodborne illness is the inability to track contaminated food back to the source in a timely manner. Although there are established methods that detect bacterial pathogen contamination, they are limited in distinguishing viable bacteria reliably and quickly. Currently, food pathogen testing requires lengthy culture steps, which many times are delayed even longer due to the lack of in-house testing labs. Typically, two to three days elapses between when the food is sampled and the test results are available. This study …


Synthesis And Characterization Of Nucleic Acid-Functionalized Nanomaterials, Brianna S. Carroll, Jong Hyun Choi Oct 2013

Synthesis And Characterization Of Nucleic Acid-Functionalized Nanomaterials, Brianna S. Carroll, Jong Hyun Choi

The Summer Undergraduate Research Fellowship (SURF) Symposium

Motor proteins such as kinesin move along microtubules in order to transport cellular cargos throughout the cell by obtaining energy from RNA hydrolysis which allows the cell to complete the tasks needed to stay alive. In this work, we developed synthetic molecular motors using DNA enzymes (DNAzyme) and fluorescent nanomaterials which mimic the functions and structures of motor proteins. A DNAzyme-capped CdS nanoparticle and a RNA-functionalized single-walled carbon nanotube (SWCNT) were used as a walker and a track in the motor platform, respectively. As a walking mechanism, the DNAzyme cleaved the RNA substrates in the presence of metal cations. The …