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Full-Text Articles in Engineering
Multi-Dimensional Extension Of The Alternating Minimization Algorithm In X-Ray Computed Tomography, Jingwei Lu
Multi-Dimensional Extension Of The Alternating Minimization Algorithm In X-Ray Computed Tomography, Jingwei Lu
McKelvey School of Engineering Theses & Dissertations
X-ray computed tomography (CT) is an important and effective tool in medical and industrial imaging applications. The state-of-the-art methods to reconstruct CT images have had great development but also face challenges. This dissertation derives novel algorithms to reduce bias and metal artifacts in a wide variety of imaging modalities and increase performance in low-dose scenarios. The most widely available CT systems still use the single-energy CT (SECT), which is good at showing the anatomic structure of the patient body. However, in SECT image reconstruction, energy-related information is lost. In applications like radiation treatment planning and dose prediction, accurate energy-related information …
Multi-Dimensional Extension Of The Alternating Minimization Algorithm In X-Ray Computed Tomography, Jingwei Lu
Multi-Dimensional Extension Of The Alternating Minimization Algorithm In X-Ray Computed Tomography, Jingwei Lu
McKelvey School of Engineering Theses & Dissertations
X-ray computed tomography (CT) is an important and effective tool in medical and industrial
imaging applications. The state-of-the-art methods to reconstruct CT images have had
great development but also face challenges. This dissertation derives novel algorithms to
reduce bias and metal artifacts in a wide variety of imaging modalities and increase performance
in low-dose scenarios.
The most widely available CT systems still use the single-energy CT (SECT), which is
good at showing the anatomic structure of the patient body. However, in SECT image
reconstruction, energy-related information is lost. In applications like radiation treatment
planning and dose prediction, accurate energy-related information …
Preclinical Imaging Of Multiple Myeloma Therapy Response, Deep Hathi
Preclinical Imaging Of Multiple Myeloma Therapy Response, Deep Hathi
McKelvey School of Engineering Theses & Dissertations
Multiple myeloma (MM) is a debilitating hematologic malignancy of terminally differentiated plasma cells in the bone marrow (BM). Advances in therapeutic regimens and the use of autologous stem cell transplantation have significantly improved survival rates and quality of life in patients. However, the disease remains incurable, with shorter, successive remission cycles following relapse. To reduce systemic, off-target toxicity and improve quality of life, there is a need for improved stratification of responding patients. Identification of specific, noninvasive, imaging biomarkers that correlate to therapeutic efficacy is an attractive strategy for stratifying responding patients, since the use of positron emission tomography (PET), …
Regularized Fourier Ptychographic Microscopy, Shiqi Xu
Regularized Fourier Ptychographic Microscopy, Shiqi Xu
McKelvey School of Engineering Theses & Dissertations
Quantitative phase image (QPI) is a popular microscopy technique for studying cell morphology. Recently, Fourier ptychographic microscopy (FPM) has emerged as a low-cost computational microscopy technique for forming high-resolution wide-field QPI images by taking multiple images from different illumination angles. However, the applicability of FPM to dynamic imaging is limited by its high data requirement. In this thesis, we propose new methods for highly compressive FPM imaging using a data-adaptive sparse coding and an online plug-and-play (PnP) method with non-local priors based on the fast iterative shrinkage/threshold algorithm (FISTA). We validate the proposed method on both simulated and experimental data …