Engineering Commons^™

Development Of Photoacoustic Tomographic Systems For Brain Hemorrhage Detection, Karl Kratkiewicz

Wayne State University Dissertations

Preterm neonates (age) and/or with low birth weight (

Photoacoustic imaging (PAI) is an imaging modality which derives its contrast from differences in optical absorption coefficients of tissue through laser irradiation and acoustic detection. Therefore, PAI derives its signal directly from optical absorbers such as blood; the critical component in a hemorrhage. We discuss operation and processing methods of our Verasonics Vantage system. We then investigate thermal safety of PAI in mouse model for various laser pulse repetitions rates and illumination duration. We then develop two photoacoustic tomographic systems for eventual translation to clinic for hemorrhage detection. One system being …

Utility Of Ultrasound/Photoacoustic Imaging For Accurate Catheter Tracking And Temperature Monitoring During Endovenous Laser Ablation, Ayushi Jharia, Keerthana Palani, Yan Yan

Research Opportunities for Engineering Undergraduates (ROEU) Program 2016-17

Laser ablation is a treatment method that uses light energy through a catheter inserted into a vein to induce localized heat to close the diseased blood vessels. Ultrasound (US) imaging has been used for catheter visualization and tracking. US has limitations for tracking the accurate location of the fiber tip inside small perforating veins such as angular dependency and comet tail artifacts. We propose a robust and accurate method for fiber tip tracking using combined US and Photoacoustic (PA) imaging to overcome the existing limitations.