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Extranodal Tumors And Chromosomal Abnormalities Associated With Non-Hodgkin Lymphoma In T(14;18)-Positive Patients, Alexis Finch May 2023

Extranodal Tumors And Chromosomal Abnormalities Associated With Non-Hodgkin Lymphoma In T(14;18)-Positive Patients, Alexis Finch

Honors Theses

Nebraska is mostly an agricultural state with a non-Hodgkin lymphoma (NHL) incidence rate of 20.1 per 100,000 individuals, which is greater than the US incidence rate of 19 per 100,000 individuals. It is possible that the higher incidence rate in Nebraska is due to an increase in pesticide usage. Pesticide exposure is linked to t(14;18), a genetic translocation involving the BCL2 gene that regulates apoptosis. The dysregulation of apoptosis could contribute to the proliferation of NHL. This exploratory study utilized the Nebraska Lymphoma Study Group, which consists of patients with non-Hodgkin lymphoma, Hodgkin disease, or some other neoplastic hematologic disorder …


The Concentration Of Heavy Metals In Lincoln Nebraska's Tap Water, Evan Neuhaus Mar 2023

The Concentration Of Heavy Metals In Lincoln Nebraska's Tap Water, Evan Neuhaus

Honors Theses

Heavy metals are commonplace in nature, and are typically found in scarce quantities in all drinking sources. However, in high enough concentrations, they can have a myriad of negative health effects. This study seeks to find the concentrations of such metals in the Lincoln water supply utilizing the resources of the Water Center at the University of Nebraska at Lincoln. To test for discrete concentrations of trace elements, a method of using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) was implemented. ICP-MS uses plasma to ionize and atomize a sample which is then filtered into a series of cones into a …


Utilizing Markov Chains To Estimate Allele Progression Through Generations, Ronit Gandhi Jan 2023

Utilizing Markov Chains To Estimate Allele Progression Through Generations, Ronit Gandhi

Honors Theses

All populations display patterns in allele frequencies over time. Some alleles cease to exist, while some grow to become the norm. These frequencies can shift or stay constant based on the conditions the population lives in. If in Hardy-Weinberg equilibrium, the allele frequencies stay constant. Most populations, however, have bias from environmental factors, sexual preferences, other organisms, etc. We propose a stochastic Markov chain model to study allele progression across generations. In such a model, the allele frequencies in the next generation depend only on the frequencies in the current one.

We use this model to track a recessive allele …


Bacteriophage That Infect Gordonia Species Show Varying Host Specificity And Infection, Lindsay Birge Mar 2022

Bacteriophage That Infect Gordonia Species Show Varying Host Specificity And Infection, Lindsay Birge

Honors Theses

Bacteriophage (phage) are an incredibly abundant species of virus that infect bacteria. One major characteristic of phage is their small host range- many phage are known to infect only one or a few hosts. This phage and host relationship has led to phage therapy recently becoming highlighted as a possible alternative to traditional antibiotics in light of the growing antibiotic resistance crisis. The study of phage host specificity has risen in line with this concept, as a phage with a more extensive host range can provide more opportunities for use as an antibiotic. Samples of phage previously isolated on a …


Can Gdp Be Predictive Of Fertility Rates In Sweden?, Hannah Coleman Jan 2022

Can Gdp Be Predictive Of Fertility Rates In Sweden?, Hannah Coleman

Honors Theses

Fertility rates in a country vary and can be influenced by numerous different aspects of an individual’s life and the society in which they live. One aspect that may influence fertility rates at the national level is the gross domestic product (GDP). GDP is an indicator of a country’s economic productivity. Because fertility is linked to both economic development and individual resources, GDP may be a useful indicator of fertility rates. If so, knowing or predicting GDP could be used to project the fertility rates of a population years into the future. To determine if a reasonable connection between GDP …


High School Biology Preparation: Do Students Feel They Have Been Adequately Prepared For Introductory College Biology?, Mara Neitzel Feb 2019

High School Biology Preparation: Do Students Feel They Have Been Adequately Prepared For Introductory College Biology?, Mara Neitzel

Empowering Research for Educators

The purpose of this study was to determine how well students are being prepared in high school for introductory college biology courses. Specifically, the objectives of the study are as follows: To gain a better understanding about how well students feel they have been prepared for college science classes based on their high school education, to gain insight on how college preparation in high school impacts students’ self-confidence, and to determine if the accessibility of advanced education courses is influenced by the size of a high school. A mixed methods survey was distributed to freshman in the fall semester of …