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Full-Text Articles in Family and Consumer Sciences
Effect Of Carnitine On The Disposition Of Alcohols, Robin Ann Ruark Brothers
Effect Of Carnitine On The Disposition Of Alcohols, Robin Ann Ruark Brothers
Doctoral Dissertations
Male Sprague-Dawley rats, 300-500g, were fed Purina rodent chow with or without a supplement of 0.5 % L-carnitine (CS or NS groups) for 5-7 days, after which they were given a single oral dose of methanol (2.25 g/kg), isopropanol (2.0 g/kg), ethylene glycol (5.56 g/kg), or ethylene glycol (5.56 g/kg) followed by ethanol (3.0 g/kg) 1 hour later in aqueous solutions. Serial blood and urine samples were collected over time and analyzed for the respective alcohols by gas chromatography. The data were subjected to pharmacokinetic analysis and statistical analysis.
There was significant reduction in blood methanol concentration in the CS …
The Effect Of Exercise, Diet Restriction And Aging On The Pituitary-Adrenal Axis In The Rat, Madeline Dellwo
The Effect Of Exercise, Diet Restriction And Aging On The Pituitary-Adrenal Axis In The Rat, Madeline Dellwo
Doctoral Dissertations
The effects of calorie restriction and exercise on feed consumption, growth, and the pituitary-adrenal axis were studied in aging male Wistar rats. The study consisted of 4 experimental groups: Sedentary, ad libitum fed controls (A); Sedentary, diet restricted by feeding on alternate days (R); Exercised by swimming on alternate days, ad libitum fed (AE); Exercised by swimming on alternate days, diet restricted by feeding on alternate days (RE).
Training effect was verified by heart weight:body weight ratio. Exercise resulted in a significantly lower body weight, in spite of the fact that exercised animals ate more than the sedentary animals. Body …