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Effects Of Larynx Preservation Method On Phonation Threshold Pressure In An Excised Porcine Benchtop Model, Chelsea Savannah Pipkin Litster
Effects Of Larynx Preservation Method On Phonation Threshold Pressure In An Excised Porcine Benchtop Model, Chelsea Savannah Pipkin Litster
Theses and Dissertations
Several studies involving excised animal larynges have been performed to simulate the structural and physiological properties of the human larynx. The most common way to preserve the laryngeal tissue being studied is by immersing it in a 0.9% isotonic saline solution and then flash freezing it. Isotonic saline is used empirically to replenish the potential ion loss that occurs postmortem. Each larynx is flash frozen so it can be used at a more convenient time while still maintaining the integrity of the tissue. However, the preservation methods found in previous studies tend to vary and no consensus had been reached …
Effects Of Larynx Preservation Method On Phonation Threshold Flow In An Excised Porcine Benchtop Model, Emily Huber Webster
Effects Of Larynx Preservation Method On Phonation Threshold Flow In An Excised Porcine Benchtop Model, Emily Huber Webster
Theses and Dissertations
An excised animal larynx model has been used in many studies to better understand the physiological and anatomical properties of the human larynx. One difference between an ex vivo model and an in vivo model is that ion loss occurs postmortem. To compensate for this in the excised model, researchers most commonly use a preservation method that includes completely submerging the specimen in isotonic saline (0.9% Na+Cl-) and then flash freezing it in liquid nitrogen. The flash freezing method allows researchers to maintain the integrity of the structures while also being able to gather specimens as they become available. Not …