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Open Access. Powered by Scholars. Published by Universities.®

2015

Illinois Math and Science Academy

STEM

Student Publications & Research

Articles 1 - 2 of 2

Full-Text Articles in Education

Using Resting-State Functional Connectivity Of The Basal Ganglia As A Biomarker For Symptoms Of Parkinson's Disease, Neal Modi '16, Lucy Yuan '16, Todd B. Parrish Apr 2015

Using Resting-State Functional Connectivity Of The Basal Ganglia As A Biomarker For Symptoms Of Parkinson's Disease, Neal Modi '16, Lucy Yuan '16, Todd B. Parrish

Student Publications & Research

Parkinson's disease (PD) is characterized by the degeneration of nigrostriatal dopaminergic neurons, resulting in dysfunctional cortico­-striato-­thalamic­cortical loops. Parkinson's disease patients suffer from chronic movement disabilities as well as cognitive impairments and other nonmotor symptoms, which implies a system­wide effect on overall brain function. Because the disease currently has no cure, the discovery of a biomarker for specific PD symptoms is crucial for monitoring treatment potency. This study aimed to evaluate the validity of using functional connectivity between regions of the basal ganglia as a biomarker for specific symptoms of PD.


Active Brain Regions During Sleep Using Electroencephalography-Functional Magnetic Resonance Imaging, Grace Duan '15, Sameeksha Malhotra '15, Todd B. Parrish Feb 2015

Active Brain Regions During Sleep Using Electroencephalography-Functional Magnetic Resonance Imaging, Grace Duan '15, Sameeksha Malhotra '15, Todd B. Parrish

Student Publications & Research

Purpose: To determine the differences in functional connectivity among brain regions during the different stages of the human sleep cycle.