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Full-Text Articles in Education
Continuous Nicotine Exposure Does Not Affect Resurgence Of Alcohol Seeking In Rats, Charles C. J. Frye, Jillian M. Rung, Rusty W. Nall, Ann Galizio, Jeremy M. Haynes, Amy L. Odum
Continuous Nicotine Exposure Does Not Affect Resurgence Of Alcohol Seeking In Rats, Charles C. J. Frye, Jillian M. Rung, Rusty W. Nall, Ann Galizio, Jeremy M. Haynes, Amy L. Odum
Psychology Faculty Publications
Alcohol is the most commonly used drug in the United States and alcohol abuse can lead to alcohol use disorder. Alcohol use disorder is a persistent condition and relapse rates following successful remission are high. Many factors have been associated with relapse for alcohol use disorder, but identification of these factors has not been well translated into preventative utility. One potentially important factor, concurrent nicotine use, has not been well investigated as a causal factor in relapse for alcohol use disorder. Nicotine increases the value of other stimuli in the environment and may increase the value of alcohol. If nicotine …
Inactivation Of The Medial-Prefrontal Cortex Impairs Interval Timing Precision, But Not Timing Accuracy Or Scalar Timing In A Peak-Interval Procedure In Rats, Catalin V. Buhusi, Marcelo B. Reyes, Cody-Aaron Gathers, Sorinel A. Oprisan, Mona Buhusi
Inactivation Of The Medial-Prefrontal Cortex Impairs Interval Timing Precision, But Not Timing Accuracy Or Scalar Timing In A Peak-Interval Procedure In Rats, Catalin V. Buhusi, Marcelo B. Reyes, Cody-Aaron Gathers, Sorinel A. Oprisan, Mona Buhusi
Psychology Faculty Publications
Motor sequence learning, planning and execution of goal-directed behaviors, and decision making rely on accurate time estimation and production of durations in the seconds-to-minutes range. The pathways involved in planning and execution of goal-directed behaviors include cortico-striato-thalamo-cortical circuitry modulated by dopaminergic inputs. A critical feature of interval timing is its scalar property, by which the precision of timing is proportional to the timed duration. We examined the role of medial prefrontal cortex (mPFC) in timing by evaluating the effect of its reversible inactivation on timing accuracy, timing precision and scalar timing. Rats were trained to time two durations in a …