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University of Nebraska - Lincoln

UReCA: The NCHC Journal of Undergraduate Research & Creative Activity

Medicine and Health Sciences

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Moving Forward With Family Centered-Care: One Step At A Time, Adrianne Dunbar Jan 2016

Moving Forward With Family Centered-Care: One Step At A Time, Adrianne Dunbar

UReCA: The NCHC Journal of Undergraduate Research & Creative Activity

Family-centered care is an evolving process between patients, families, and health care providers. The family centered care model emphasizes the strength families bring to the healing process. The research project was a quasi-experimental pre-and post-test study with a communication intervention phase. The study was conducted in a Surgical-Trauma Intensive Care Unit (STICU) in a university affiliated hospital in the Southeast with restricted visitation hours. The purpose of this IRB-approved study was to measure the nurses’ perceptions of communication involvement with family members before and after the intervention phase. Approximately 50% of eligible participants responded. The communication intervention phase consisted of …


Connexin-43 And Traumatic Brain Injury: A Potential Target For Therapeutic Intervention, Lauren R. Moore Jan 2016

Connexin-43 And Traumatic Brain Injury: A Potential Target For Therapeutic Intervention, Lauren R. Moore

UReCA: The NCHC Journal of Undergraduate Research & Creative Activity

Traumatic Brain Injury (TBI) is a widespread, degenerative affliction with no current therapeutic interventions. The long-term degradation caused by TBI results from secondary injury cascades that are initiated by primary injury. An early and important step in the damage process is reactive astrogliosis in astrocytes. Astrocytes communicate through gap junctions, which are composed of two connexon hemichannels from the two communicating cells and these connexons themselves are composed of six connexin protein subunits. Connexin 43 (Cx43) is a particularly important connexin to gap junctional communication and could act either to preserve the astrocytes from oxidative stress, or to propagate the …