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Brigham Young University

Theses and Dissertations

Theses/Dissertations

2021

Benchtop model

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Full-Text Articles in Education

Variability Of The Aerodynamic Measures Of Leporine Larynges Exposed To Inhaled Corticosteroids, Miriam Angela Cannon Bake Jun 2021

Variability Of The Aerodynamic Measures Of Leporine Larynges Exposed To Inhaled Corticosteroids, Miriam Angela Cannon Bake

Theses and Dissertations

This thesis examined the effects of combination inhaled corticosteroids (ICs) on the stability of six aerodynamic measures of phonation utilizing a traditional benchtop model with leporine larynges. The motivation for this study was based on the increase of voice disorders associated with IC use in recent years. The aerodynamic measures examined were phonation threshold pressure (PTP), phonation threshold flow (PTF), onset resistance, sustained pressure, sustained flow, and sustained resistance. Leporine larynges were selected as the model for this study due to histological similarities between leporine and human vocal folds that make them ideal for translational research. Rabbits were either exposed …


Phonation Threshold Pressure And Phonation Threshold Flow In Rabbits Treated With Inhaled Corticosteroids Versus Controls, Heidi Joan Robison Apr 2021

Phonation Threshold Pressure And Phonation Threshold Flow In Rabbits Treated With Inhaled Corticosteroids Versus Controls, Heidi Joan Robison

Theses and Dissertations

This thesis is part of a larger series of studies being conducted by Kristine Tanner, PhD, Associate Professor in the Department of Communication Disorders at Brigham Young University (BYU). The larger project is funded by the National Institute on Deafness and Other Communication Disorders at the National Institutes of Health. This thesis primarily investigated the effects of combination inhaled corticosteroids (ICs) on aerodynamic measures of the voice. In recent years, an increase in the localized laryngeal side effects from IC treatment, including dysphonia, have been reported. This study employed a between-groups experimental design, with two groups of rabbit larynges having …