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Effects Of Inhaled Combination Corticosteroid Drugs On Aerodynamic Measures Of Phonation And Visual-Perceptual Measures Of Vocal Fold And Arytenoid Tissue In Excised Rabbit Larynges, Christina Lynn Pang
Effects Of Inhaled Combination Corticosteroid Drugs On Aerodynamic Measures Of Phonation And Visual-Perceptual Measures Of Vocal Fold And Arytenoid Tissue In Excised Rabbit Larynges, Christina Lynn Pang
Theses and Dissertations
The purpose of this thesis is to examine the effects of inhaled corticosteroid drugs (ICs) on the voice due to their frequent use in treating an increasing prevalence of asthma disorders. As part of a larger five-year study, the focus of this thesis is specifically on whether 8 weeks of in vivo exposure to ICs will cause changes in the sustained subglottal pressure, sustained airflow, and visual-perceptual ratings of edema and erythema in excised rabbit larynges. Researchers administered either ICs or a control nebulized isotonic saline solution to 22 rabbits in vivo, sacrificed them, and harvested their larynges for benchtop …
Phonation Threshold Pressure And Phonation Threshold Flow In Rabbits Treated With Inhaled Corticosteroids Versus Controls, Heidi Joan Robison
Phonation Threshold Pressure And Phonation Threshold Flow In Rabbits Treated With Inhaled Corticosteroids Versus Controls, Heidi Joan Robison
Theses and Dissertations
This thesis is part of a larger series of studies being conducted by Kristine Tanner, PhD, Associate Professor in the Department of Communication Disorders at Brigham Young University (BYU). The larger project is funded by the National Institute on Deafness and Other Communication Disorders at the National Institutes of Health. This thesis primarily investigated the effects of combination inhaled corticosteroids (ICs) on aerodynamic measures of the voice. In recent years, an increase in the localized laryngeal side effects from IC treatment, including dysphonia, have been reported. This study employed a between-groups experimental design, with two groups of rabbit larynges having …