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Alkene Ozonolysis In The Academic Lab, Patrick Dussault
Alkene Ozonolysis In The Academic Lab, Patrick Dussault
Organic Peroxides: Safety Issues
The following information is offered as a guide based upon our experience with application of ozone for organic oxidations and hydroperoxide synthesis. Please send suggestions, requests, or corrections to pdussault1@unl.edu.
Introduction and leading references
Overview of ozonolysis: Mechanism, Substrate reactivity, Typical reaction conditions, Reaction monitoring, Reaction work-ups
Safety Issues
Acknowledgements:
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The following provides a brief introduction to the application of ozonolysis within academic labs. Ozonolysis remains among the most frequently used of methods for oxidative cleavage of alkenes. While best known as a means by which to introduce aldehydes and ketones, ozonolysis can also be used to generate other …