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The Clinical Effectiveness Of Concise Cognitive Behavioral Therapy With Or Without Pharmacotherapy For Depressive And Anxiety Disorders; A Pragmatic Randomized Controlled Equivalence Trial In Clinical Practice, Denise Meuldijk, Ingrid V. Carlier, Irene M. Van Vliet, T Van Veen, R Wolterbeek, Albert M. Van Hemert, Frans G. Zitman
The Clinical Effectiveness Of Concise Cognitive Behavioral Therapy With Or Without Pharmacotherapy For Depressive And Anxiety Disorders; A Pragmatic Randomized Controlled Equivalence Trial In Clinical Practice, Denise Meuldijk, Ingrid V. Carlier, Irene M. Van Vliet, T Van Veen, R Wolterbeek, Albert M. Van Hemert, Frans G. Zitman
Faculty of Social Sciences - Papers (Archive)
Background: Depressive and anxiety disorders contribute to a high disease burden. This paper investigates whether concise formats of cognitive behavioral- and/or pharmacotherapy are equivalent with longer standard care in the treatment of depressive and/or anxiety disorders in secondary mental health care. Methods: A pragmatic randomized controlled equivalence trial was conducted at five Dutch outpatient Mental Healthcare Centers (MHCs) of the Regional Mental Health Provider (RMHP) 'Rivierduinen'. Patients (aged 18-65 years) with a mild to moderate anxiety and/or depressive disorder, were randomly allocated to concise or standard care. Data were collected at baseline, 3, 6 and 12 months by Routine Outcome …
Economic Evaluation Of Concise Cognitive Behavioural Therapy And/Or Pharmacotherapy For Depressive And Anxiety Disorders, Denise Meuldijk, Ingrid V. Carlier, Irene M. Van Vliet, Albert M. Van Hemert, Frans G. Zitman, M E. Van Den Akker-Van Marle
Economic Evaluation Of Concise Cognitive Behavioural Therapy And/Or Pharmacotherapy For Depressive And Anxiety Disorders, Denise Meuldijk, Ingrid V. Carlier, Irene M. Van Vliet, Albert M. Van Hemert, Frans G. Zitman, M E. Van Den Akker-Van Marle
Faculty of Social Sciences - Papers (Archive)
BACKGROUND: Depressive and anxiety disorders cause great suffering and disability and are associated with high health care costs. In a previous conducted pragmatic randomised controlled trial, we have shown that a concise format of cognitive behavioural- and/or pharmacotherapy is as effective as standard care in reducing depressive and anxiety symptoms and in improving subdomains of general health and quality of life in secondary care psychiatric outpatients. AIMS OF THE STUDY: In this economic evaluation, we examined whether a favourable cost-utility of concise care compared to standard care was attained. METHODS: The economic evaluation was performed alongside a pragmatic randomised controlled …
A Randomized Controlled Trial Of The Efficacy And Cost-Effectiveness Of A Brief Intensified Cognitive Behavioral Therapy And/Or Pharmacotherapy For Mood And Anxiety Disorders: Design And Methods, Denise Meuldijk, Ingrid V. Carlier, Irene M. Van Vliet, M E. Van Den Akker-Van Marle, Frans G. Zitman
A Randomized Controlled Trial Of The Efficacy And Cost-Effectiveness Of A Brief Intensified Cognitive Behavioral Therapy And/Or Pharmacotherapy For Mood And Anxiety Disorders: Design And Methods, Denise Meuldijk, Ingrid V. Carlier, Irene M. Van Vliet, M E. Van Den Akker-Van Marle, Frans G. Zitman
Faculty of Social Sciences - Papers (Archive)
Background: Anxiety and mood disorders involve a high disease burden and are associated with high economic costs. A stepped-care approach intervention and abbreviated diagnostic method are assumed to increase effectiveness and efficiency of the mental healthcare and are expected to reduce economic costs. Methods: Presented are the rationale, design, and methods of a two-armed randomized controlled trial comparing 'treatment as usual' (TAU) with a brief intensified cognitive behavioral therapy (CBT) and/or pharmacotherapy. Eligible participants (N =500) of five Dutch outpatient Mental Healthcare Centers are randomly assigned to either TAU or to the experimental condition (brief CBT and/or pharmacotherapy). Data on …