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Physicochemical Properties Of Blend Poly (Vinyl Alcohol) And Sodium Alginate Membranes For Potential Application In Wound Dressings, Martha Pieper
Physicochemical Properties Of Blend Poly (Vinyl Alcohol) And Sodium Alginate Membranes For Potential Application In Wound Dressings, Martha Pieper
Mechanical Engineering Theses
Poly (vinyl alcohol) (PVA) and sodium alginate (SA) are water-soluble polymers with excellent biocompatibility suitable for biomedical applications in wound dressings. In this study, pure PVA, pure SA, and blends of PVA/SA membranes were solvent cast into films followed by crosslinking in CaCl2, boric acid, and a mixture of CaCl2/boric acid solutions for 5, 10, and 30 minutes. Initial feasibility studies showed a strong correlation of film thickness to the observed mechanical properties. Further studies in solvent casting of blend PVA/SA films, using various polymer concentrations, yielded better film appearance with minimal physical changes after crosslinking. …