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Life Sciences

1992

Claudia A Kirk

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Effect Of Glipizide On Serum Insulin And Glucose Concentrations In Healthy Cats, A Miller, R Nelson, Claudia Kirk, L Neal, E Feldman Dec 1991

Effect Of Glipizide On Serum Insulin And Glucose Concentrations In Healthy Cats, A Miller, R Nelson, Claudia Kirk, L Neal, E Feldman

Claudia A Kirk

With the recent identification of non-insulin-dependent diabetes mellitus (NIDDM) in cats, new possibilities arise for the use of oral hypoglycaemic agents in the treatment of feline NIDDM, similar to their use in humans. To identify the future applicability of the oral hypoglycaemic agent, glipizide, in the treatment of feline NIDDM, its effects on serum insulin and glucose concentrations in healthy cats was examined. In addition, adverse effects seen clinically or on bloodwork following short-term use of the drug were looked for. Serum insulin and glucose concentrations were evaluated after the oral administration of 2.5, 5.0 and 10.0 ...