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Reduced Risk Of Alzheimer's Disease In Users Of Antioxidant Vitamin Supplements: The Cache County Study, Peter P. Zandi, James C. Anthony, Ara S. Khachaturian, Stephanie V. Stone, Deborah Gustafson, Joann T. Tschanz, Maria C. Norton, John C. S. Breitner
Reduced Risk Of Alzheimer's Disease In Users Of Antioxidant Vitamin Supplements: The Cache County Study, Peter P. Zandi, James C. Anthony, Ara S. Khachaturian, Stephanie V. Stone, Deborah Gustafson, Joann T. Tschanz, Maria C. Norton, John C. S. Breitner
Psychology Faculty Publications
Background: Antioxidants may protect the aging brain against oxidative damage associated with pathological changes of Alzheimer disease (AD). Objective: To examine the relationship between antioxidant supplement use and risk of AD. Design: Cross-sectional and prospective study of dementia. Elderly (65 years or older) county residents were assessed in 1995 to 1997 for prevalent dementia and AD, and again in 1998 to 2000 for incident illness. Supplement use was ascertained at the first contact. Setting: Cache County, Utah. Participants: Among 4740 respondents (93%) with data sufficient to determine cognitive status at the initial assessment, we identified 200 prevalent cases of AD. …