Business Commons^™

This paper examines how the concept of public values can be operationalized in an ongoing public initiative to stimulate innovation in an emerging technology. Our study focuses on Innovation Corps (I-Corps)—a program initiated in 2011 by the National Science Foundation (NSF) to accelerate the process of commercializing science-driven discoveries. The I-Corps method has since spread rapidly across multiple US agencies. Separately, there has also been heightened attention to the early anticipation and mitigation of the implications of emerging science and technology. Drawing on the case of nanotechnology, the paper considers how public values related to nanotechnology commercialization can be integrated …

A goal of synthetic biology bio-foundries is to innovate through an iterative design/build/test/learn pipeline. In assessing the value of new chemical production routes, the intellectual property (IP) novelty of the pathway is important. Exploratory studies can be carried using knowledge of the patent/IP landscape for synthetic biology and metabolic engineering. In this paper, we perform an assessment of pathways as potential targets for chemical production across the full catalogue of reachable chemicals in the extended metabolic space of chassis organisms, as computed by the retrosynthesis-based algorithm RetroPath. Our database for reactions processed by sequences in heterologous pathways was screened against …