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Evaluation Of Cholera Vaccines Formulated With Toxin-Coregulated Pilin Peptide Plus Polymer Adjuvant In Mice, Jia-Yan Wu, William F. Wade, Ronald K. Taylor

Dartmouth Scholarship

Cholera is an acute diarrheal disease that is caused by the gram-negative bacterium Vibrio cholerae. The low efficacy of currently available killed-whole-cell vaccines and the reactinogenicity coupled with potential reversion of live vaccines have thus far precluded widespread vaccination for the control of cholera. Recent studies on the molecular nature of the virulence components that contribute to V. cholerae pathogenesis have provided insights into possible approaches for the development of a defined subunit cholera vaccine. Genetic analysis has demonstrated that the toxin-coregulated pilus (TCP) is the major factor that contributes to colonization of the human intestine by V. cholerae. In …

Immune Response Genes Modulate Serologic Responses To Vibrio Cholerae Tcpa Pilin Peptides, Michael D. Meeks, Terri K. Wade, Ronald K. Taylor, William F. Wade

Dartmouth Scholarship

Cholera is an enteric disease caused by Vibrio cholerae. Toxin-coregulated pilus (TCP), a type 4 pilus expressed by V. cholerae, is a cholera virulence factor that is required for host colonization. The TCP polymer is composed of subunits of TcpA pilin. Antibodies directed against TcpA are protective in animal models of cholera. While natural or recombinant forms of TcpA are difficult to purify to homogeneity, it is anticipated that synthesized TcpA peptides might serve as immunogens in a subunit vaccine. We wanted to assess the potential for effects of the immune response (Ir) gene that could complicate a peptide-based …

Access To Pediatric Services Under Medicaid Managed Care In The District Of Columbia, Karen Shaw, Sara J. Rosenbaum

Health Policy and Management Faculty Publications

No abstract provided.

Metastatic Prostate Cancer Associated With Lumbar Compression Fracture And Spinal Stenosis: A Casereport And Literature Review, Shwu-Fen Sun, Jue-Long Wang, Ping-Hong Lai

Rehabilitation Practice and Science

We reported a 72 y/o male who had past history of old L1 compression fracture for 1 year. He suffered from falling down accidentally and was operated under impression of L1 burst fracture with cauda equina syndrome. He could ambulate with walker, but persistent back pain was still complained. Two months after operation, he became paralyzed rapidly in 2 days. Neurological examinations showed decreased motor strength of bilateral lower extremities to grade 0-1/5, sensory deficit below T10 dermatome and bilateral extensor plantar response. X-ray film showed an osteoblastic lesion in T9 vertebra body. Magnetic resonance Imaging (MRI) of thoracic spine …

The Interaction Between Antidepressants And Spasticity Of Stroke: Casereport, Shih-Wen Lin, Zong-Jing Wang, Young-Hue Yu

Rehabilitation Practice and Science

The upper motor neuron diseases (such as cerebrovascular accidents, traumatic brain injury, spinal cord injury, and multiple sclerosis) frequently cause spasticity of extremities. The medications for treating spasticity include baclofen and diazepam, which take their effect in the central nervous system through their GABAergic action. The incidence of depression in patients with spasticity is much higher than that of the normal population. Many doctors prescribe antidepressants for these patients. Two common used antidepressants are tricyclic antidepressants (TCA) and selective serotonin reuptake inhibitors (SSRI). They could increase serotonin amount in synapses, and induce increased excitability of motor neurons, which in turn …

A Design Of Rehabilitation Information System For Inpatients: An Experience Of A Medical Center, Mu-Jung Kao, Chih-Tsung Hsieh, Rong-Lin Yang, Mei-Wun Tsai

Rehabilitation Practice and Science

Rehabilitation Information System for Inpatients (RISI) was designed for medical administration in the Department of Rehabilitation at a medical center in Taiwan. The RISI includes administration system, patient consultation system, rehabilitation order entry system, rehabilitation therapy system for physical therapy, occupational therapy, and speech therapy, check out system for time and frequency of therapy, and statistic function system.The characteristics of this system includes: 1) integration of systems between outpatients and inpatients; 2) integration of available administration system and patient consultation system; 3) integration of administration and medical system in the department of rehabilitation and 4) operation without paper work. The …

Clinical Experience In Asian Type Multiple Sclerosis, Der-Sheng Han, Jau-Jia Lin, Yen-Ho Wang, Chih-Chao Yang

Rehabilitation Practice and Science

Multiple sclerosis is a heterogeneous disease entity, and also the most common disabling neurological disorder of people in middle life in USA. The prevalence of multiple sclerosis in Asia is lower than that in Western countries of similar latitude. Besides, there are some different features, clinically as well as pathologically, between this disease in Asia and in Western countries. We collected 27 cases diagnosed as clinically definite MS at NTUH between 1990-2000, whose clinical presentations are restricted to optic nerves and spinal cord. Their clinical charts were reviewed retrospectively, and the data was collected in a standard coding sheet. The …

Bacteremia Associated With Early Childhood Caries, Eddie Chang

Loma Linda University Electronic Theses, Dissertations & Projects

Previous research has investigated the post-operative bacteria levels caused by a variety of clinical procedures such as anesthetic injections, standard dental procedures, endodontic treatment, periodontal surgery, root scaling, and oral surgical procedures in children. Other studies have suggested that bacteremias are often caused by oral infections. Although numerous studies have examined how oral infections lead to various medical conditions (i.e. brain abscess) none have studied the potential for preoperative bacteremia that may arise in conjunction with early childhood caries (ECC). The purpose of this study was to compare potential systemic facultative and anaerobic bacteria found in otherwise healthy children who …

Rumination And Cigarette Smoking: A Bad Combination For Depressive Outcomes?, Malia Richmond, Bonnie Spring, Beth Kaplan Sommerfeld, Dennis E. Mcchargue

Department of Psychology: Faculty Publications

Ruminative coping has been shown to heighten the risk and severity of depression. The authors hypothesized that ruminators who smoke would experience greater depressive symptoms than ruminators who do not. The rationale is that, by heightening attentional focus, nicotine may increase ruminators' ability to focus on negative thoughts, augmenting depressed mood. Participants (N = 145) self-reported smoking status, rumination, and current and lifetime depressive symptoms, including depressed mood. Results showed that rumination accounted for a larger amount of variance in current and past depressed mood and severity of lifetime depressive symptoms among smokers than nonsmokers. Noncorrelational, experimental research should …

Genital Tract Lesions And The Isolation Of Ureaplasma Diversum From The Reproductive Tract Of Normal And Repeat Breeding Dairy Cows, Prachin Virakul, Kraiwan Hongyantarachai, Kitti Mahaviroon, Saroch Ngarmkum, Phornchai Suwannaphirom, Vinai Krasaesinthugomol, Ayuth Harintharanont, Santi Prasithphol, Pairoj Ampawanwong, Junpen Suwimonteerabutr

The Thai Journal of Veterinary Medicine

This study was conducted in 78 dairy cows(50 repeat breeders and 28 normal cows, with no history of breeding difficulty) from 6 livestock regions of Thailand. Observations were made on the lesions of granular vulvitis and bacteriology performed in order to isolate Ureaplasma diversum. Swabs were taken from 3 sites; the clitoral fossa, the dorsal vulva lips and the external cervical osteum. The isolation of U. diversum was carried out using Taylor Robinson Medium. In the repeat breeding group, U. diversum was isolated from 46% of the clitoral swabs, 48% of the vulva lip swabs and 22% of the external …

Ultrasound Diagnosis, Phiwipha Kamonrat

The Thai Journal of Veterinary Medicine

No abstract provided.

What Is Your Diagnosis?, Pranee Tuntivanich

The Thai Journal of Veterinary Medicine

No abstract provided.

Physical Activity Research In Nursing, Lorraine B. Robbins, Nola J. Pender, Vicki S. Conn, Marilyn Frenn, Geri B. Neuberger, Mary A. Nies, Robert V. Topp, Joellen Wilbur

College of Nursing Faculty Research and Publications

Purpose: To present exemplars of physical activity research in nursing, illustrate the importance of physical activity research across the lifespan, and recommend directions for theory development and research.

Methods: Studies of physical activity and exercise currently being conducted by nurse investigators were reported and critiqued by attendees of the Midwest Nursing Research Society 2000 Preconference session entitled “Promoting Physical Activity Among Diverse Groups Across the Health Continuum.” Physical activity and exercise literature during the past decade was reviewed. Databases searched included Medline, CINAHL, Wilson, and ERIC.

Findings: Investigators have emphasized the need to evaluate the effects of theory-based physical activity …

Multimodal Assessment Of The Effect Of Chewing Gum On Nicotine Withdrawal, Lee M. Cohen, Dana M. Britt, Frank L. Collins, Mustafa Al-Absi, Dennis E. Mcchargue

Department of Psychology: Faculty Publications

The present study was designed to evaluate the usefulness of chewing gum to reduce nicotine withdrawal, craving, and salivary cortisol concentrations during temporary nicotine deprivation. A total of 20 male smokers were studied under conditions when gum was and was not accessible during a 4-hour deprivation period. All subjects smoked an initial cigarette shortly after arrival for the two experimental sessions and were informed that they would be unable to smoke for the remainder of each session. The sessions consisted of each subject watching a movie, then waiting in the lab for two consecutive 30-min intervals. Self-reported nicotine withdrawal and …

Secondary Cancer From Primary Cancer Treatment-I: Risk Assessment And Overview, P. Kachonrattanadet, N. Voravud

Chulalongkorn Medical Journal

No abstract provided.

The Pizzi Holistic Wellness Assessment, Michael Pizzi

Occupational Therapy Faculty Publications

This paper describes the Pizzi Holistic Wellness Assessment tool. Using theory from the field of health promotion and expertise gained in his private home health practice, the author developed and pilot tested this assessment on a variety of individuals. The assessment is designed to be used with different populations in a variety of settings to help clients self assess their health and well-being.

Long-Term Outcome Of Gastrostomy Feeding In Dysphagic Stroke Patients, Tung-Chou Li, Mei-Hue Hsu, Tzong-Hsi Lee

Rehabilitation Practice and Science

Dysphagia is a common reason for long-term enteral feeding in stroke patients. It has been shown that gastrostomy feeding provides better nutrition for stroke patients than nasogastric tube feeding in short term period. However, little is known about the long-term outcome of gastrostomy-assisted feeding in them. In recent years, some of the dysphagic stroke patients began to accept gastrostomy feeding in Taiwan. We herein conducted this study to find and analyze the characteristics and long-term outcome of dysphagic stroke patients who had underwent gastrostomy. Forty-two stroke patients underwent gastrostomy between Jan. 1998 and May 2000 were enrolled in this study. …

Anatomy And Three-Dimensional Reconstructions Of The Brain Of The White Whale (Delphinapterus Leucas) From Magnetic Resonance Images, Lori Marino, Timothy L. Murphy, Amy L. Deweerd, John A. Morris, Archibald J. Fobbs, Nathalie Humbolt, Sam H. Ridgway, John I. Johnson

Veterinary Science and Medicine Collection

Magnetic resonance imaging offers a means of observing the internal structure of the brain where traditional procedures of embedding, sectioning, staining, mounting, and microscopic examination of thousands of sections are not practical. Furthermore, internal structures can be analyzed in their precise quantitative spatial interrelationships, which is difficult to accomplish after the spatial distortions often accompanying histological processing. For these reasons, magnetic resonance imaging makes specimens that were traditionally difficult to analyze, more accessible. In the present study, images of the brain of a white whale (Beluga) Delphinapterus leucas were scanned in the coronal plane at 119 antero-posterior levels. Fromthese scans, …

Effect Of Monounsaturated Fat Rich Almonds On Hemostatic And Inflammatory Factors In Healthy Adults, Kristianne M. Connell

Loma Linda University Electronic Theses, Dissertations & Projects

Background: The frequent consumption of nuts is inversely associated with the incidence of cardiovascular disease. Nuts are known to decrease the risk of cardiovascular disease by reducing serum total and low-density lipoprotein (LDL) cholesterol. Markers of inflammation including C-reactive protein, E-selectin and interleukin-6 have been proposed to be newer risk factors for cardiovascular disease. However, the influence of nuts such as almonds on markers of inflammation and hemostasis that influence cardiovascular disease risk is not currently known.

Objective: The objective of this study was to determine the effect of almond consumption on markers of inflammation and hemostatic factors in healthy …

Factors Influencing Puberty Attainment In Gilts And Policies That Can Improve Mating Efficiency In Replacement Gilts, Padet Tummaruk, Wichai Tantasuparuk, Mongkol Techakumphu, Annop Kunavongkrit

The Thai Journal of Veterinary Medicine

The objective of this study is to review the information regarding the development of puberty in gilts and how it influences subsequent reproductive performance such an understanding can be used to improve mating efficiency in gilts. The percentage of gilts in a herd strongly influences overall productivity. The first management decision that has to be made about gilts entering the breeding herd, is the timing of the first breeding. This largely depends on when puberty develops. Puberty in gilts is defined as the time when the first oestrus and ovulation occurs followed by regular oestrous cycles. On average, gilts attain …

Immunohistochemical Detection Of Feline Viral Rhinotracheitis In A Cat, Nopadon Pirarat, Yumi Une, Yasuo Nomura

The Thai Journal of Veterinary Medicine

A female, 10-month old, mixed breed cat showed clinical signs of severe dehydration, purulent nasal discharge, dyspnea, severe crepitating lung sounds and no response to antibiotic treatment. Upon necropsy, histopathology revealed severe, diffuse, fibrinopurulent pleuropneumonia and numerous, homogeneous, amphophilic, intranuclear inclusion bodies in the pulmonary alveolar macrophages, bronchial and alveolar epithelium and bronchial glandular epitheliums. Immunohistochemical studies using 3 different monoclonal, anti-Feline Herpesvirus type 1 antibodies, revealed immunoreactivity of viral antigen in the lung that was associated with the histopathological changes. Monoclonal, anti-glycoprotein B, antibody showed the strongest immunoreactivity.

Ecg Quiz, Chollada Buranakarl, Kris Angkanaporn, Sumpun Thammacharoen, Phiwipha Kamonrat

The Thai Journal of Veterinary Medicine

No abstract provided.

Effects Of A Serine 364 To Proline Mutation Of The Connexin43 Protein In Transgenic Mice, Chia-Ling Nhan-Chang

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

Relationship Between Nursing Nutrition Knowledge And Attitudes And Identification Of Malnutrition In The Acute Care Setting, Susan D. Kendziorski

Masters Theses

Malnutrition is widespread in healthcare and effective protocols are needed to identify those at risk. Nurses are well suited to carry out screening for malnutrition because they are in close contact with the patient and are responsible to coordinate each patient's care. In order to perform this role nurses must have nutrition knowledge and the skills to complete an accurate nutrition screen. The purpose of this study was to examine relationships between nursing nutrition knowledge, nursing attitudes towards nutrition, and the accurate completion of a nutrition screening protocol. Patient's charts were reviewed for accurate completion of the nutrition screening protocol …

Etiology And Rehabilitation Effect Of Stroke In Child: A Casereport, Li-Chen Tung, Kwok-Tak Yeung, Chun-Hou Wang, Wen-I Liang, Liu-Ing Bih

Rehabilitation Practice and Science

The incidence of strokes in childhood is 2.5/100,000. Of these, occlusive stroke accounts for 57 to 85 percent, and hemorrhagic stroke accounts for 15 to 51 percent. Occlusive stroke is primarily caused by congenital heart defects, and the principal symptom is acute hemiplegia. Hemorrhagic stroke is caused mostly by abnormalities of blood vessels, and is characterized by headache and loss of consciousness. Compared to adults, children have better collateral circulation and incompletely developed brains. The clinical and recovery courses those in children are different from those of adults. The prognosis and the incidence of stroke recurrence are largely determined by …

The Effect Of Lead Acetate On The Susceptibility Of C3heb/Fej Mice Infected With The Parasite Trypanosoma Cruzi, Savonna Warren

Masters Theses & Specialist Projects

Lead has been mined by man for centuries with evidence of its use dating back 6000 years. Chronic exposure to lead can result in encephalopathy, anemia, and nephropathy. Today, cases of lead poisoning are uncommon; however, lead continues to be incorporated into the body through subclinical exposures. These low dosages of lead have been shown to have a deleterious effect on the immune system. Experimental animals exposed to low levels of lead are unable to effectively respond to a number of bacterial and viral challenges. The present study focuses on the relationship between lead and parasitic infection. Parasitemia, mortality, serum …

Expression Of Gus Gene In Tobacco (Nicotiana Tabacum) And Corn (Zea Mays) Using Dimboa-Resistant Agrobacterium Strains, Deepti Mohamalawari

Masters Theses & Specialist Projects

This thesis evaluates the ability of Agrobacterium tumefaciens strains resistant to the compound DIMBOA [2, 4-dihydroxy-7-methoxy-2h-l,4- benzoxazin-3(4H)-one] to infect corn. DIMBOA is a secondary plant metabolite and is believed to have antimicrobial properties and provides resistance to the plant against microbial infection. Agrobacteriummediated genetic transformation technique can be employed to genetically alter most dicotyledonous plant species. However, such transformation has been limited in monocotyledonous plants, especially corn. One of the factors responsible for this recalcitrance is the presence of DIMBOA in corn shoots. In this study, we proposed the use of DIMBOA- resistant strains of Agrobacterium tumefaciens, bearing binary plasmids …

Evaluation Of Directly Observed Therapy In Pulmonary Tuberculosis Patients In Nepal: Treatment Outcome And Patient Compliance, Baishali Bhattacharya

Masters Theses & Specialist Projects

Tuberculosis is the leading cause of infectious disease in Nepal. An estimated 60% of the adult population aged between 15-45 years is infected with tuberculosis, and 45% of the total population is infected. Ten percent of people infected with TB progress to active disease. To combat tuberculosis, Directly Observed Therapy (DOT) was adopted in Nepal in 1996. DOT was administered at four national demonstration sites in 1996 and expanded over time so that 56% of the population to date have been covered by DOT. This study aimed to evaluate DOT in pulmonary TB patients in Nepal in terms of patient …

Temporal, Perspectives, Dispositional Styles, And Subjective Well-Being, Mary Naeger

Masters Theses & Specialist Projects

This study investigated the relationship between time perspective (TP) and the personality dispositions of optimism, pessimism, and realism with regard to their proposed influence on three measures that collectively assessed subjective well-being (SWB). The Depression-Happiness Scale (McGreal & Joseph, 1993) assessed happiness or the presence of positive affect and the absence of negative affect, the cognitiveaffective components of SWB. The Satisfaction with Life Scale (SWLS) (Diener, Emmons, Larsen, & Griffin, 1985) provided the measurement of subjective life satisfaction, the essential final cognitive-judgmental component of SWB. The Life Orientation Scale-Revised (LOT-R) (Scheier, Carver, and Bridges, 1994) and a Reality Scale, composed …

Inheritance Of Dorsal Fin Coloration In The Metriaclima Species Complex (Teleostei: Cichlidae) Of Lake Malawi, Paulette Reneau

Masters Theses & Specialist Projects

The rock-dwelling cichlids (mbuna) of Lake Malawi have undergone an explosive evolution, giving rise to an assemblage of 300-500 species within the last one million years. Most widespread mbuna 'species' are characterized by the presence of local endemic populations, differing primarily in coloration and often of uncertain taxonomic rank. The recency and rapidity of speciation within the mbuna have led to difficulties in reconstructing an accurate species-level phylogeny, in turn limiting our ability to elucidate the evolutionary dynamics associated with divergence of coloration and other characters. Based on morphometric and meristic characters, Stauffer et al. (1997) erected a new genus …