Digital Commons Network^™

Problems Of Training Qualified Personnel For The Sphere Of Physical Culture And Sports, Abdimalik Nurullaevich Shopulatov

Eurasian Journal of Sport Science

Purpose: To study the issues aimed at increasing the knowledge and experience in the effective use of physical culture and sports in the restoration of public health, as well as to analyze the work being done to train qualified personnel in the field of physical culture and sports and identify problems.

Methods: Methods such as analysis of scientific and methodological literature, pedagogical observation, questionnaire were used in the study.

Results: From the research it was revealed that today it is important to develop the knowledge of the population on physical education and sports, that is, to create educational and scientific …

The Effect Of Twist1b And Twist2 Knockdown On Tgf-Beta Signaling Expression In Tendon Progenitors, Marinia N. Bishay

Honors Scholars Collaborative Projects

Somites are important mesoderm structures that form in regularly timed intervals from the anterior end of the paraxial mesoderm at the end of gastrulation during embryogenesis. Cells of the ventromedial portion of the somite, the sclerotome, undergo epithelial to mesenchymal transition, surround the notochord, and give rise to connective tissues of the axial skeleton including the vertebrae, tendons, and ligaments. We are interested in understanding how the sclerotome is compartmentalized into the region that makes tendons. Genes expressed in the sclerotome, twist1 and twist2, are likely involved in the downstream differentiation of sclerotome to tendon progenitors. Previous studies have shown …

Multiple Approaches To Auditory Rhythm: Development Of Sustained Musical Beat And The Relation To Language, Development Of Rhythmic Categories Via Iterated Production, And A Meta-Analytic Study Of Neural Entrainment To Beat, Karli Marie Nave

UNLV Theses, Dissertations, Professional Papers, and Capstones

Rhythm is ubiquitous to human communication, coordination, and experience of music. In this dissertation, I address three empirical questions through three different methodologies, all of which contribute to the growing body of literature on human auditory rhythm processing. In Chapter 2, I present a registered report detailing the results of independent conceptual replications of Nozaradan, Peretz, Missal, & Mouraux (2011), all using the same vetted protocol. Listeners performed the same tasks as in Nozaradan et al. (2011), with the addition of behavioral measures of perception. In neuroscience, neural correlates to musical beat perception have been identified, yet little to no …

The Interactions Between Oral Biofilms, Antibiotic Resistance, And Dentistry, Maxine Taylor

Honors Projects

Antibiotic resistance is a pressing concern that demands further action to reduce and develop new countermeasures. Antibiotic resistance impacts all fields of health and medicine, including dentistry. Many of the preventive and restorative dental procedures are due to a bacterial cause. Knowledge of oral biofilm development mechanisms and the interactions and relationships between oral microbiota is necessary to combat the spread of antibiotic resistance and develop more effective dental treatments. Exploring how the oral microbiomes and their treatments impact the health of the rest of the body is another important consideration since dentistry is part of the general healthcare system. …

Strained Differentiation: Negotiating Grief With Maternal Foundations In Laird Hunt’S Neverhome, Heidie L. Raine

Channels: Where Disciplines Meet

The intertwinement of mother-daughter psyches throughout the early developmental process bonds maternal and filial parties up unto differentiation, at which point the child comes to understand her status as an individual and her mother’s status as a separate entity. However, when trauma is introduced midway through the differentiation process, this psychological phenomenon may be hindered, stunting the advanced personal development of the daughter. Abandoned by loss, she may subconsciously fall victim to repressive defenses, insufficient socialization, and destructive behaviors.

In his 2016 novel Neverhome, Laird Hunt explores these psychological factors through a traumatized and unreliable female protagonist situated in …

Navigating The Pandemic As It Enters Its Second Year, Havovi Joshi

Asian Management Insights

Many countries, enabled by the rapid vaccine rollout, experienced some moments of relief from the Covid-19 pandemic as they embarked on their long and winding transition toward normalcy. However, despite the Herculean effort expended, achieving herd immunity remains a distant goal for many due to the emergence of the highly transmissible and lethal Delta variant and the persistence of vaccine hesitancy. As such, the coronavirus continues to upend lives, businesses, and society, and the playbook for survival will still be a work-in-progress

Pharmaceutical Potential Of Laboratory Grown Cultures Of Blue-Green Algae: A Comprehensive Review And Future Possibilities, Ritu Chauhan, Abhishek Chauhan, Ashutosh Tripathi, Anuj Ranjan, Subhash C. Chauhan, Tanu Jindal

School of Medicine Publications and Presentations

COVID-19 pandemic has taught the world researchers the urgent need for new sources and novel pharmaceuticals not only for existing diseases but also for both seasonal epidemics and future pandemics. Pharmaceutical drug discoveries for the past fifty years depended deeply on the procedure of empirical transmission of a huge number of pure bioactive compounds to provide new leads. The screening of extracts or isolating compounds is a common way to discover novel biologically active molecules. Most of the valuable Blue-Green algal metabolites are concentrated in their biomass. For existence in nature, Blue-Green algae (BGA) secrete and contain various organic substances …

Expression Profile Analysis Of Micrornas During The Oestrous Cycle Of Qira Black Sheep, Xi Chen, Hanying Chen, Song Jiang, Chaocheng Li, Xiancun Zeng

The Thai Journal of Veterinary Medicine

Ovarian follicular development is closely regulated by a multitude of genes and specific non-coding RNAs (ncRNAs), which are typically altered during the oestrous cycle. Identification of the microRNAs (miRNA) expression profiles in sheep ovaries during the oestrous cycle is a prerequisite to further understanding their functional status. This study presents a genome-wide analysis of miRNAs from three groups of Qira black sheep: oestrus (day 0), dioestrus (day 10) and pro-oestrus (day 14). A total of 545 conserved miRNAs and 206 novel miRNAs were identified. Furthermore, 229 differentially expressed miRNAs were screened in three comparisons and 16 miRNAs were found to …

Bridging The Gap Between Muscle And Bone: Examining Tendon Identity And Development, Amel Sassi

Undergraduate Student Research Internships Conference

Tendons are fibrous connective tissues that connect skeletal muscle to bone. Functioning primarily to facilitate locomotion, these tissues are rich with collagen and other minor collagens and proteoglycans. Nevertheless, with over 4000 tendons in the human body, the molecular pathways that define different tendons remain largely unknown. As such, the clear distinction between tendon identity, particularly at the genetic level has yet to be fully established. Similarly, molecular pathways involved in tendon developments remain to be fully elucidated. Despite the important role of tendons in motor coordination and posture, a number of areas in tendon development and identity have yet …

The Development And Implementation Of A Culturally Safe Survey For Measuring Knowledge, Attitudes And Values Around Fasd And Alcohol Use During Pregnancy In A Remote Australian Aboriginal Community Setting, Martyn Symons, David Tucker, Kaashifah Bruce, Annalee Stearne, Annette Kogolo, Maureen Carter, June Oscar, Glenn Pearson, James P. Fitzpatrick

Australian Indigenous HealthBulletin

Fetal Alcohol Spectrum Disorder (FASD) describes a lifelong neurodevelopmental disability caused by prenatal alcohol exposure that has a devastating impact on individuals, families and communities. The prevalence of FASD is high in some Indigenous communities around the World and the only active case ascertainment prevalence study conducted in Australia found a rate of 19.44 per 100 children in the remote Fitzroy Valley region of Western Australia. Following this study community led FASD prevention activities were implemented under the Marulu (“Worth Nurturing”) Strategy in the Fitzroy Valley.

A Knowledge, Attitudes and Practices survey was designed to assess the impact of the …

Disease, Development, And Disorder: Examining The Effect Of Health On Subnational Development And Conflict In Sub-Saharan Africa, Dlorah C. Jenkins

Doctor of International Conflict Management Dissertations

Progress towards achieving the Sustainable Development Goals (SDGs) has been uneven across and within countries - particularly in Africa, least developed countries, and low-income countries. The COVID-19 pandemic has threatened to reverse much of the progress made towards achieving the SDGs, especially SDG 3, which aims to “ensure healthy lives and promote well-being for all at all ages”.

The tendency for disease, underdevelopment, and conflict to occur concomitantly suggests potential causal mechanisms linking them. This study attempts to address two pieces of the puzzle: the causal effect of disease on underdevelopment and the impact of development on conflict risk. Focusing …

Observing And Promoting Normative Developmental Outcomes: Reciprocity Is Key, Nicki L. Aubuchon-Endsley, Bryan M. Gee, Heather L. Ramsdell, Nancy Devine, Hillary E. Swann-Thomsen, Nicholas Burgett, Leah R. Kollmeyer, Michele R. Brumley

The Open Journal of Occupational Therapy

Background: Occupational therapists focus on caregiver-infant reciprocity, which is influenced by a host of biopsychosocial factors and is predictive of developmental outcomes across domains. It is important for early intervention professions to understand how different forms of reciprocity may predict infant development in salient domains (i.e., language, mobility, and co-occupation). Therefore, the purpose of this study was to investigate associations among related measures of development in and across age, while also exploring how reciprocity influences the acquisition of developmental milestones.

Method: We examined these important areas of development in relation to novel caregiver-infant co-occupational constructs in addition to …

Evaluation Of A Dirfloortime® Program For Autism Spectrum Disorder, Jennifer L. Pipitone

Dissertations

Problem. Parents with children who have neurodevelopmental disorders, such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) experience high levels of parenting stress. The prevalence of ASD is on the rise in the United States. As a result, there has been an increase in the use of treatment modalities, in effort to better understand which modalities have the most positive impact on children and their parents. DIRFloortime® is a developmental treatment modality used to help strengthen the parent-child bond and used to decrease parental-child stress. The Autism Parenting Stress Index (APSI) measures the impact of an intervention …

Transcriptomic Changes And The Roles Of Cannabinoid Receptors And Pparγin Developmental Toxicities Following Exposure To Δ9-Tetrahydrocannabinol And Cannabidiol, Zacharias Pandelides, Neelakanteswar Aluru, Cammi Thornton, Haley E. Watts

Faculty and Student Publications

Human consumption of cannabinoid-containing products during early life or pregnancy is rising. However, information about the molecular mechanisms involved in early life stage Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) toxicities is critically lacking. Here, larval zebrafish (Danio rerio) were used to measure THC- and CBD-mediated changes on transcriptome and the roles of cannabinoid receptors (Cnr) 1 and 2 and peroxisome proliferator activator receptor γ(PPARγ) in developmental toxicities. Transcriptomic profiling of 96-h postfertilization (hpf) cnr+/+ embryos exposed (6 - 96 hpf) to 4 μM THC or 0.5 μM CBD showed differential expression of 904 and 1095 genes for THC and CBD, respectively, …

The Developmental Plasticity Of Fruit Fly Vision, John Paul Currea

FIU Electronic Theses and Dissertations

In this dissertation we explore the morphological and neural plasticity underlying vision at different scales—within and between species of Drosophila—to elucidate the role of eye development in the evolution of vision. In chapter 2, we offer a tool to accelerate large-scale research into compound eye morphology, and validate it on the eyes of several insect orders and image media. Then, in chapter 3 we demonstrate the developmental plasticity of eye morphology and neural summation in fruit flies, finding an interesting interplay between the two systems. In chapter 4, we elucidate the role of visual plasticity and neural summation in the …

Leader Development Of The Health Information Management (Him) Professional, Theresa Jones

Dissertations

This study contributes to the body of knowledge in leader development by examining how higher education programs in a female dominated profession assist learners in developing person-related characteristics that support leader development. A ten-part online survey was sent to directors of health information management (HIM) programs accredited by the Commission on Accreditation for Health Informatics and Information Management (CAHIIM). Results suggest an opportunity for improvement in the curriculum for development of person-related characteristics critical for leadership positions. In the interest of the progression of women these results should be taken into consideration.

The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan

University Scholar Projects

The granule cells are the most abundant neuronal type in the human brain. Rapid proliferation of granule cell progenitors results in dramatic expansion and folding of the cerebellar cortex during postnatal development. Mis-regulation of this proliferation process causes medulloblastoma, the most prevalent childhood brain tumor. In the developing cerebellum, granule cells are derived from Atoh1-expressing cells, which arise from the upper rhombic lip (the interface between the roof plate and neuroepithelium). In addition to granule cells, the Atoh1 lineage also gives rise to different types of neurons including cerebellar nuclei neurons. In the current study, I have investigated the …

The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan

Honors Scholar Theses

The granule cells are the most abundant neuronal type in the human brain. Rapid proliferation of granule cell progenitors results in dramatic expansion and folding of the cerebellar cortex during postnatal development. Mis-regulation of this proliferation process causes medulloblastoma, the most prevalent childhood brain tumor. In the developing cerebellum, granule cells are derived from Atoh1-expressing cells, which arise from the upper rhombic lip (the interface between the roof plate and neuroepithelium). In addition to granule cells, the Atoh1 lineage also gives rise to different types of neurons including cerebellar nuclei neurons. In the current study, I have investigated the …

Rethink Everything 2: Markets, Globalization, Development, Nikhilesh Dholakia, Deniz Atik

Markets, Globalization & Development Review

No abstract provided.

The Role Of Cannabinoid Receptor 2 In Zebrafish Toxicities Following Developmental Exposure To Thc Or Cbd, Haley Watts

Honors Theses

As the laws concerning the regulation of Cannabis Sativa change across the globe, maternal use of cannabinoid-containing products during pregnancy is a greater concern than ever before. Little research has been conducted on the consequences of maternal use and developmental exposure to ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD. In this study, larval zebrafish (Danio rerio) were used to measure CBD and THC-mediated adverse outcomes including effects on larval length, eye area, and behavior in the cnr^+/+ and cnr2^-/- zebrafish strains where we discovered that cannabinoid exposure results in a decrease in each of these endpoints. Adult …

Developmental Effects Due To Childhood Sexual Abuse, Kaitlyn Nguyen, Jenny Chang

Nursing | Senior Theses

Childhood development is a crucial component in the life of any individual. Any disturbances or abnormalities present during childhood may cause adverse outcomes later in life. Nurses play a pivotal role as the patient’s advocate and even more importantly, they are the last line of defense in all aspects of care. Therefore, gaining deeper insight into the patient’s histories is vitally important to nurses as they work to ensure the best health outcomes. For this investigation, nursing science students focused on the detrimental effects that childhood sexual abuse has on the mental and physical development throughout the aging process. After …

Role Of Occupational Therapy In The Nicu And Post-Nicu Settings, Katlyn M. Schochenmaier

Occupational Therapy Capstone Presentations

The purpose of this capstone experience was to gain advanced clinical experience and explore occupational therapy’s role in the NICU and post-NICU settings. Further focus of this capstone was on the feeding concerns and sensory development of infants following a NICU stay. This capstone project was completed at a Level IV NICU and an outpatient speech and occupational therapy clinic in a midwestern city. Theoretical models of Ayres’ Sensory Integration, Neonatal Integrative Developmental Care Model, and Biopsychosocial Model of Pediatric Feeding were used to develop and implement this capstone experience. A two-day continuing education course was completed prior to the …

Culminating Project In Program Development: Resources For Occupational Engagement For Families And Educators Of Children With Autism Spectrum Disorder, Catherine Lane

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.

Law Library Blog (April 2021): Legal Beagle's Blog Archive, Roger Williams University School Of Law

Law Library Newsletters/Blog

No abstract provided.

Genetic Influences On Externalizing Psychopathology Overlap With Cognitive Functioning And Show Developmental Variation, Josephine Mollon, Emma E. M. Knowles, Samuel R. Mathias, Amanda Rodrigue, Tyler M. Moore, Monica E. Calkins, Ruben C. Gur, Juan M. Peralta, Daniel J. Weiner, John Blangero, Laura Almasy

School of Medicine Publications and Presentations

Background: Questions remain regarding whether genetic influences on early life psychopathology overlap with cognition and show developmental variation.

Methods: Using data from 9,421 individuals aged 8-21 from the Philadelphia Neurodevelopmental Cohort, factors of psychopathology were generated using a bifactor model of item-level data from a psychiatric interview. Five orthogonal factors were generated: anxious-misery (mood and anxiety), externalizing (attention deficit hyperactivity and conduct disorder), fear (phobias), psychosis-spectrum, and a general factor. Genetic analyses were conducted on a subsample of 4,662 individuals of European American ancestry. A genetic relatedness matrix was used to estimate heritability of these factors, and genetic correlations with …

The Evolutionary Conserved Swi/Snf Subunits Arid1a And Arid1b Are Key Modulators Of Pluripotency And Cell-Fate Determination, Luca Pagliaroli, Marco Trizzino

Department of Biochemistry and Molecular Biology Faculty Papers

Organismal development is a process that requires a fine-tuned control of cell fate and identity, through timely regulation of lineage-specific genes. These processes are mediated by the concerted action of transcription factors and protein complexes that orchestrate the interaction between cis-regulatory elements (enhancers, promoters) and RNA Polymerase II to elicit transcription. A proper understanding of these dynamics is essential to elucidate the mechanisms underlying developmental diseases. Many developmental disorders, such as Coffin-Siris Syndrome, characterized by growth impairment and intellectual disability are associated with mutations in subunits of the SWI/SNF chromatin remodeler complex, which is an essential regulator of transcription. ARID1B …

Is Covid-19 Pushing Us To The Fifth Industrial Revolution (Society 5.0)?, Zouina Sarfraz, Azza Sarfraz, Hamza M. Iftikar, Ramsha Akhund

Department of Paediatrics and Child Health

The coronavirus disease 2019 (COVID-19) pandemic may further promote the development of Industry 4.0 leading to the fifth industrial revolution (Society 5.0). Industry 4.0 technology such as Big Data (BD) and Artificial Intelligence (AI) may lead to a personalized system of healthcare in Pakistan. The final bridge between humans and machines is Society 5.0, also known as the super-smart society that employs AI in healthcare manufacturing and logistics. In this communication, we review various Industry 4.0 and Society 5.0 technologies including robotics and AI being inspected to control the rate of transmission of COVID-19 globally. We demonstrate the applicability of …

Comparing Neural Correlates Of Conditioned Inhibition Between Children With And Without Anxiety Disorders - A Preliminary Study, Anita Harrewijn, Elizabeth R. Kitt, Rany Abend, Chika Matsumoto, Paola Odriozola, Anderson M. Winkler, Ellen Leibenluft, Daniel S. Pine, Dylan G. Gee

School of Medicine Publications and Presentations

Cognitive-behavioral therapy (CBT), a first-line treatment for pediatric anxiety disorders, is based on principles of threat learning and extinction. However, CBT does not work sufficiently for up to 40% of clinically anxious youth. The neural and behavioral correlates of conditioned inhibition might provide promising targets for attempts to improve CBT response. During conditioned inhibition, threat and safety cues appear together, forming a safety compound. Here, we test whether this safety compound elicits a reduced fear response compared to pairing the threat cue with a novel cue (novel compound). The current pilot study compares behavioral, physiological, and neural correlates of conditioned …

A Systematic Review Of Brainstem Contributions To Autism Spectrum Disorder, Ala Seif, Carly Shea, Susanne Schmid, Ryan A Stevenson

Anatomy and Cell Biology Publications

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects one in 66 children in Canada. The contributions of changes in the cortex and cerebellum to autism have been studied for decades. However, our understanding of brainstem contributions has only started to emerge more recently. Disruptions of sensory processing, startle response, sensory filtering, sensorimotor gating, multisensory integration and sleep are all features of ASD and are processes in which the brainstem is involved. In addition, preliminary research into brainstem contribution emphasizes the importance of the developmental timeline rather than just the mature brainstem. Therefore, the purpose of this systematic review …

The Effect Of Nutrition Education On Dietary Knowledge And Fruit And Vegetable Consumption In Children, Colleen A. Thompson

DNP Research Projects

No abstract provided.