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Feeding Deficits Contributing To Picky Eating, Olivia Paige Allen, Brianna Paige Pestrosky, Caitlyn Shaffer Apr 2024

Feeding Deficits Contributing To Picky Eating, Olivia Paige Allen, Brianna Paige Pestrosky, Caitlyn Shaffer

Graduate Student Scholarship

Children are often known as picky eaters but many aspects contribute to feeding that one may not be aware of. These factors include sensory, oral motor, behavioral, neuromuscular, social skills, developmental readiness, and functional feeding skills. This study analyzes the aspects of feeding that contribute to picky eating and examines why some aspects may contribute more than others. The study will be conducted through the use of observation and standardized occupational therapy assessments while looking at children ages 2-10 years old. The goal of the study is to increase the knowledge of picky eating by relating it to the various …


A Longitudinal Study Of The Development Of Social Anxiety In Young Autistic Children, Gillian K. Marshall Apr 2024

A Longitudinal Study Of The Development Of Social Anxiety In Young Autistic Children, Gillian K. Marshall

Senior Theses

Social anxiety is a prevalent anxiety disorder marked by fear and discomfort in social situations where scrutiny or evaluation by others is anticipated. This thesis investigates the interplay between social anxiety and autism spectrum disorder (ASD), a neurodevelopmental condition characterized by social and communication challenges. Individuals with ASD often face heightened levels of anxiety, intensifying their social difficulties and impeding their social development. Early identification of social anxiety symptoms, particularly in ASD children, is crucial for timely intervention and improved outcomes. However, diagnosing social anxiety in preschool-aged children, especially those with ASD, presents challenges due to the complexity of symptoms …


Annual Research Review: The Power Of Predictability – Patterns Of Signals In Early Life Shape Neurodevelopment And Mental Health Trajectories, Elysia Poggi Davis, Laura M. Glynn Feb 2024

Annual Research Review: The Power Of Predictability – Patterns Of Signals In Early Life Shape Neurodevelopment And Mental Health Trajectories, Elysia Poggi Davis, Laura M. Glynn

Psychology Faculty Articles and Research

The global burden of early life adversity (ELA) is profound. The World Health Organization has estimated that ELA accounts for almost 30% of all psychiatric cases. Yet, our ability to identify which individuals exposed to ELA will develop mental illness remains poor and there is a critical need to identify underlying pathways and mechanisms. This review proposes unpredictability as an understudied aspect of ELA that is tractable and presents a conceptual model that includes biologically plausible mechanistic pathways by which unpredictability impacts the developing brain. The model is supported by a synthesis of published and new data illustrating the significant …


Development Of A Medication Compliance Determinant Instrument For Low-Middle Literate Patients With Type 2 Diabetes Mellitus, Ivans Panduwiguna, Rani Sauriasari, Ratu Ayu Dewi Sartika, Woro Riyadina, Fransiskus Samuel Renaldi Aug 2023

Development Of A Medication Compliance Determinant Instrument For Low-Middle Literate Patients With Type 2 Diabetes Mellitus, Ivans Panduwiguna, Rani Sauriasari, Ratu Ayu Dewi Sartika, Woro Riyadina, Fransiskus Samuel Renaldi

Kesmas

Diabetes, a leading cause of 6.7 million deaths in 2021, poses a significant challenge despite existing interventions. Non-adherence to treatment remains a barrier to diabetes management. However, a comprehensive instrument to assess medication adherence determinants in diabetes patients’ population in Indonesia with low-medium literacy levels and following the sociocultural characteristics of Indonesian society has been lacking. This study aimed to develop and evaluate a valid and reliable instrument for measuring medication adherence in type 2 diabetes mellitus patients based on the Borg and Gall model. Through the input of an expert panel, a valid and reliable instrument was developed, which …


The Biocompatibility Of A Ginger-Containing Herbal Toothpaste On Developing Zebrafish Embryos, Simge Meseli, Unsal Veli Ustundag, Perihan Seda Ates, Ismail Unal, Ebru Isik Alturfan, Dilek Tağtekin, Funda Yanikoglu Aug 2023

The Biocompatibility Of A Ginger-Containing Herbal Toothpaste On Developing Zebrafish Embryos, Simge Meseli, Unsal Veli Ustundag, Perihan Seda Ates, Ismail Unal, Ebru Isik Alturfan, Dilek Tağtekin, Funda Yanikoglu

Journal of Dentistry Indonesia

The biocompatibility of toothpaste in an oral cavity should be approved by clinical trials. Nowadays, herbal toothpaste is increasing in popularity due to its natural ingredients. Being genetically similar to humans, zebrafish are used in potential toxicity testing. The zebrafish embryotoxicity test is a fast and straightforward method to study chemical toxicity during embryogenesis.

Objective: This study aimed to evaluate if there was any biocompatibility of the toothpaste on zebrafish embryos.

Methods: Adult AB strain zebrafish were used according to Institutional Animal Care and Use Committee protocols. Normally dividing, spherical embryos were exposed to herbal toothpaste with ginger (Gumgumix, Turkey) …


An Occupation Based Program: Supporting Mothers Through Pregnancy And Postpartum, Precious Barnett, Monica Watford, La'shandra Russell Aug 2023

An Occupation Based Program: Supporting Mothers Through Pregnancy And Postpartum, Precious Barnett, Monica Watford, La'shandra Russell

Summer 2023 Virtual OTD Capstone Symposium

This capstone project aimed to discover the effects of occupational therapy services with women who may experience or who are at risk for postpartum depression. Supporting Mothers Through Pregnancy and Postpartum is the developed capstone program. This program included occupation-based activities and resources to encourage occupational participation and engagement. This program used an integrative approach to support the participants of this project. This poster presentation includes background information regarding this population, the methods used to develop the program, program topic themes and goals, and links to view the program’s deliverables.


Neurotropic Manifestations As A Potential Risk Factor For Schizophrenia Following In Utero Exposure To Sars-Cov-2, Mir Ali R Talpur, Omar H. Elsayed, Rif S. El-Mallakh Jul 2023

Neurotropic Manifestations As A Potential Risk Factor For Schizophrenia Following In Utero Exposure To Sars-Cov-2, Mir Ali R Talpur, Omar H. Elsayed, Rif S. El-Mallakh

The University of Louisville Journal of Respiratory Infections

Background: COVID-19 infection is associated with neurologic and psychiatric morbidity that suggests a direct effect of the virus or secondary effect of an inflammatory process. These neuropsychiatric consequences may increase the likelihood of schizophrenia in the offspring of women who become infected with COVID-19 during their pregnancy.

Methods: We performed a directed narrative review of the literature focusing on the proposed pathophysiological processes that lead to schizophrenia and known pathological consequences of COVID-19 infection.

Results: Schizophrenia in adult offspring has been associated with maternal infections during pregnancy by a wide range of respiratory and neurotropic pathogens. Spikes in the incidence …


The Building Healthy Eating And Self-Esteem Together For University Students Mobile App To Treat Eating Disorders: User-Centered Research Design And Feasibility Study., Kelsie T. Forbush, Kara A. Christensen Pacella, Marianna L. Thomeczek, Sara R. Gould, Danielle A N Chapa, Brianne N. Richson, Victoria L. Perko, Joseph Ayres, Yiyang Chen, Sonakshi Negi Jul 2023

The Building Healthy Eating And Self-Esteem Together For University Students Mobile App To Treat Eating Disorders: User-Centered Research Design And Feasibility Study., Kelsie T. Forbush, Kara A. Christensen Pacella, Marianna L. Thomeczek, Sara R. Gould, Danielle A N Chapa, Brianne N. Richson, Victoria L. Perko, Joseph Ayres, Yiyang Chen, Sonakshi Negi

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: University students are an at-risk group for the development of eating disorders (EDs); however, many college campuses lack sufficient resources to provide ED specialty care. Students report unique reasons for not seeking ED treatment, including the desire to solve the problem on their own (eg, seeking help from friends, self-medicating, or waiting to see if their problems improve), inability to afford treatment, lack of time to participate in the treatment, fear of seeing their primary care physician, and lack of recognition of their issues as an ED. Mobile health (mHealth) apps may be a cost-effective, helpful adjunctive tool to …


Water-Fat Magnetic Resonance Imaging For The Assessment Of Human Fetal Adipose Tissue, Stephanie A. Giza Jul 2023

Water-Fat Magnetic Resonance Imaging For The Assessment Of Human Fetal Adipose Tissue, Stephanie A. Giza

Electronic Thesis and Dissertation Repository

Adipose tissue is crucial for providing heat and energy to infants, especially at transitions such as birth and therefore must begin developing in utero. This development may be altered due to an adverse uterine environment, increasing the risk of developing later-life metabolic diseases such as obesity. An early assessment of fetal adipose tissue development through lipid accumulation could be key to understanding metabolic programming and minimizing this risk.

Water-fat magnetic resonance imaging (MRI) can non-invasively measure the lipid concentration of tissues and can therefore monitor the development of adipose tissue via tissue lipid concentration. This work demonstrated the feasibility …


A Short Report On The Impact Of Judo On Behaviors And Social Skills Of Children With Autism Spectrum Disorder., Blake S. Lockard, Marissa Dallara, Chasity O'Malley Jul 2023

A Short Report On The Impact Of Judo On Behaviors And Social Skills Of Children With Autism Spectrum Disorder., Blake S. Lockard, Marissa Dallara, Chasity O'Malley

HPD Articles

INTRODUCTION: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by communication difficulty and social deficits. The current treatment employs the use of psychosocial therapy and medication as well as alternative treatments. This is a pilot study that assessed whether participation in judo improved behavior and social skills in children with ASD.

METHODS: Twenty-four students from the Riverside Youth Judo Club were included in the study, after obtaining consent from their parents to participate. Inclusion criteria included participation in judo classes for more than one month and diagnosis of ASD and/or a developmental disability. Parent(s) of the children signed a …


Understanding The Consumption Of Antimicrobial Resistance–Related Content On Social Media: Twitter Analysis, Hyunuk Kim, Chris R. Proctor, Dylan Walker, Ronan R. Mccarthy Jun 2023

Understanding The Consumption Of Antimicrobial Resistance–Related Content On Social Media: Twitter Analysis, Hyunuk Kim, Chris R. Proctor, Dylan Walker, Ronan R. Mccarthy

Business Faculty Articles and Research

Background: Antimicrobial resistance (AMR) is one of the most pressing concerns in our society. Today, social media can function as an important channel to disseminate information about AMR. The way in which this information is engaged with depends on a number of factors, including the target audience and the content of the social media post.

Objective: The aim of this study is to better understand how AMR-related content is consumed on the social media platform Twitter and to understand some of the drivers of engagement. This is essential to designing effective public health strategies, raising awareness about antimicrobial …


Developmental Boxes, Karina Ryabinina, Lauren Kelly, Marissa Bankey, Kaila Medeiros, Sammy Schultz May 2023

Developmental Boxes, Karina Ryabinina, Lauren Kelly, Marissa Bankey, Kaila Medeiros, Sammy Schultz

Nursing Leadership in Community Engagement Projects

Developmental Boxes

The assigned facility is a resource center that operates to assist families in need. Services offered include housing placement, homelessness prevention, securement of affordable childcare, after-school programs, and health education. The center has served the Mount Baker community for nearly three years and intends to continue partnering with public services to end the cycle of poverty and create brighter futures for those who need it most (Mercy Housing, 2021).

Our team conducted a windshield survey of the community served by the facility and determined there to be limited access to childcare in the area as well as minimal …


International Strategies For Addressing The Needs Of Children With Disabilities: Comparing Pediatric Therapy Services In Italy And The United States, Cassidy Hearn, Lillian Hsiao, Lavinia Fanelli, Regina Harbourne May 2023

International Strategies For Addressing The Needs Of Children With Disabilities: Comparing Pediatric Therapy Services In Italy And The United States, Cassidy Hearn, Lillian Hsiao, Lavinia Fanelli, Regina Harbourne

Physical Therapy Projects

This paper introduces and compares the professions of Neuro and Psychomotor Therapist of Developmental Age and pediatric physical therapy. Although pediatric physical therapy practice is prevalent in the United States, Italy utilizes another profession which encompasses many features of physical therapy, but also incorporates neuropsychological factors, specifically for children.


The History Of Geriatric Emergency Medicine, Teresita M. Hogan Md, Lowell Gerson Phd, Aurthur B. Sanders Md Apr 2023

The History Of Geriatric Emergency Medicine, Teresita M. Hogan Md, Lowell Gerson Phd, Aurthur B. Sanders Md

Journal of Geriatric Emergency Medicine

Abstract: Excellent emergency care does not happen by chance. The standard emergency approach that excels in the young, fails in older patients. Older adults experience unnecessary morbidity and excess mortality in our emergency departments. This article describes the pursuit of excellent emergency care in the historically challenging older adult population. A pivotal point occurred once emergency physicians recognized older patients as a distinct population in need of unique evaluation and treatment.

In the early 1990s a group of geriatricians, philanthropists, and emergency physicians joined forces to improve older patient care. Geriatric Emergency Medicine (GEM) emerged as a subspecialty as these …


Learn, Reflect, Practice, Discuss: A Professional Development Pilot For Clinical Nurse Educators, Jessica Savage, Linda Wofford Dr., David Phillippi Dr. Apr 2023

Learn, Reflect, Practice, Discuss: A Professional Development Pilot For Clinical Nurse Educators, Jessica Savage, Linda Wofford Dr., David Phillippi Dr.

DNP Scholarly Projects

Abstract

AIM: The aim of this project was to assess the effect of a professional development pilot on the self-efficacy among clinical nurse educators toward evaluation and assessment of students in the clinical setting.

BACKGROUND: Nursing schools employ clinical nurse faculty with varied levels of experience and formal education in teaching. Positive student outcomes are dependent on the competency of their nursing faculty, yet best practices to train and support the professional growth of clinical faculty have not yet been identified.

METHOD: A multi-modal professional development pilot including online-learning modules, self-reflection, practice-learning, and peer-mentoring components was designed and implemented with …


Developmental Changes In Electrophysiological Properties Of Auditory Cortical Neurons In The Cntnap2 Knockout Rat, Rajkamalpreet S Mann, Brian L Allman, Susanne Schmid Apr 2023

Developmental Changes In Electrophysiological Properties Of Auditory Cortical Neurons In The Cntnap2 Knockout Rat, Rajkamalpreet S Mann, Brian L Allman, Susanne Schmid

Anatomy and Cell Biology Publications

Disruptions in the CNTNAP2 gene are known to cause language impairments and symptoms associated with autism spectrum disorder (ASD). Importantly, knocking out this gene in rodents results in ASD-like symptoms that include auditory processing deficits. This study used in vitro patch-clamp electrophysiology to examine developmental alterations in auditory cortex pyramidal neurons of Cntnap2-/- rats, hypothesizing that CNTNAP2 is essential for maintaining intrinsic neuronal properties and synaptic wiring in the developing auditory cortex. Whole cell patch-clamp recordings were conducted in wildtype and Cntnap2-/- littermates at three postnatal age ranges (P8-12, P18-21, and …


Occupational Therapy's Role In Infant Feeding & Postpartum Support, Megan Gallagher Apr 2023

Occupational Therapy's Role In Infant Feeding & Postpartum Support, Megan Gallagher

Occupational Therapy Doctoral Student Capstone Posters

A smooth transition to parenthood requires education and preparation on what to expect and new roles, responsibilities, and occupations. This capstone, in collaboration with Nurture Columbus, developed educational resources for new parents to help meet their infant feeding goals and facilitate a smooth transition throughout the postpartum period. In addition, education for healthcare professionals on the distinct value of occupational therapy during the perinatal period is included.


Improving The Delivery Of Developmental Care In The Nicu: A Focus On Co-Occupational Engagement, Christina Martella Apr 2023

Improving The Delivery Of Developmental Care In The Nicu: A Focus On Co-Occupational Engagement, Christina Martella

Occupational Therapy Doctoral Student Capstone Posters

The role of the parent being the primary caregiver is interrupted in the NICU by the advanced care the infant is being provided. These parental role alterations that NICU caregivers experience can negatively impact the parent-infant relationship and ultimately negatively impact overall parental engagement. Even with increased literature showing the need for developmental care through co-occupational engagement with NICU families, it is not systematically integrated into everyday practice. This capstone project aimed to create a systematic way to improve Occupational Therapists’ approach to delivering high quality developmental care through co-occupational parent engagement within the Neonatal Intensive Care Unit.


Prenatal Buprenorphine Exposure Reduces Expression Of Myelin Proteins In Neonatal Longs-Evans Rat, Christopher James Grahe Jan 2023

Prenatal Buprenorphine Exposure Reduces Expression Of Myelin Proteins In Neonatal Longs-Evans Rat, Christopher James Grahe

Theses, Dissertations and Capstones

In the USA and especially in WV, there has been a surge in the rise of opioid use disorder (OUD), and with it a rise in neonatal abstinence syndrome (NAS). What makes this rise in NAS so unfortunate is that the Medications for OUD (MOUD) do not prevent the development of NAS. Although the relationship between MOUD and NAS is still unclear, it is thought that buprenorphine, one of the main substances used to treat OUD in pregnant women, may feed into the development of NAS, which may affect mental and physiological development and cause other health problems. Via understanding …


Progression Of Dyad Mentorship To Work Driven Model: Is This A Value Addition?, Rehana Rehman, Tazeen Saeed Ali, Rahila Ali Jan 2023

Progression Of Dyad Mentorship To Work Driven Model: Is This A Value Addition?, Rehana Rehman, Tazeen Saeed Ali, Rahila Ali

Department of Biological & Biomedical Sciences

No abstract provided.


New Leader Mentorship Program Preparing Frontline Nurse Leaders For Success, Melanie S. Smith-Fortney Jan 2023

New Leader Mentorship Program Preparing Frontline Nurse Leaders For Success, Melanie S. Smith-Fortney

Walden Dissertations and Doctoral Studies

A new nurse leader often enters their role with minimal training. The absence of a structured orientation leaves new leaders without the advanced knowledge and skills needed to succeed in this complex role, increasing the risk of stress and burnout. This staff education project addressed whether providing the educational framework found within the American Organization for Nurse Leaders (AONL) nurse manager competencies would improve nurses’ knowledge to lead departmental operations and personnel for the new nurse leader. Duchscher’s stages of transition theory focused on the emotional aspects of transitioning into a new role. The AONL Nurse Leader Competency Assessment Tool: …


Synaptic Development In Diverse Olfactory Neuron Classes Uses Distinct Temporal And Activity-Related Programs, Michael A. Aimino, Alison T. Depew, Lucas Restrepo, Timothy J. Mosca Nov 2022

Synaptic Development In Diverse Olfactory Neuron Classes Uses Distinct Temporal And Activity-Related Programs, Michael A. Aimino, Alison T. Depew, Lucas Restrepo, Timothy J. Mosca

Farber Institute for Neuroscience Faculty Papers

Developing neurons must meet core molecular, cellular, and temporal requirements to ensure the correct formation of synapses, resulting in functional circuits. However, because of the vast diversity in neuronal class and function, it is unclear whether or not all neurons use the same organizational mechanisms to form synaptic connections and achieve functional and morphologic maturation. Moreover, it remains unknown whether neurons united in a common goal and comprising the same sensory circuit develop on similar timescales and use identical molecular approaches to ensure the formation of the correct number of synapses. To begin to answer these questions, we took advantage …


Language Development And Disorders, Sudhin Karuppali Dr. Nov 2022

Language Development And Disorders, Sudhin Karuppali Dr.

Health collection

The field of language development and its disorders is a widely researched area in the field of speech-language pathology. However, language development in the Indian population is vaguely studied, probably because of the diversity of languages and cultures in this country. This has time and again resulted in difficulties in estimating the language levels of children with language impairments, consequently becoming challenging to prepare customized interventional plans. The lack of standardized language assessment tools has always been a concern in clinical practice. This lacuna in establishing accurate language levels has been observed in the adolescent population as well, which is …


Moderating Factors In The Relationship Between Bully Victimization And Psychosomatic Symptoms, Tonya Paulson Oct 2022

Moderating Factors In The Relationship Between Bully Victimization And Psychosomatic Symptoms, Tonya Paulson

Theses and Graduate Projects

The purpose of this study was to investigate the relationship between bully victimization and psychosomatic symptoms, and to examine the protective influence of perceived parent and peer support across developmental age groups. Bully victimization frequency, somatic symptom severity, perceived parent support, and perceived peer support were assessed using archival data from 7,304 youth who participated in the 2009-2010 Health Behavior in School-Aged Children (HBSC) U.S. survey, excluding perpetrators of bullying. Bully victimization and somatic symptoms were significantly positively correlated. Older adolescents consistently reported more severe somatic symptoms, but age did not moderate the relationship between bullying and somatic symptoms. Higher …


Early Life Exposure To Unpredictable Parental Sensory Signals Shapes Cognitive Development Across Three Species, Elyssia Poggi Davis, Kari Mccormack, Hina Arora, Desiree Sharpe, Annabel K. Short, Jocelyne Bachevalier, Laura M. Glynn, Curt A. Sandman, Hal S. Stern, Mar Sanchez, Tallie Z. Baram Oct 2022

Early Life Exposure To Unpredictable Parental Sensory Signals Shapes Cognitive Development Across Three Species, Elyssia Poggi Davis, Kari Mccormack, Hina Arora, Desiree Sharpe, Annabel K. Short, Jocelyne Bachevalier, Laura M. Glynn, Curt A. Sandman, Hal S. Stern, Mar Sanchez, Tallie Z. Baram

Psychology Faculty Articles and Research

Exposure to early life adversity has long term consequences on cognitive function. Most research has focused on understanding components of early life adversities that contribute to later risk, including poverty, trauma, maltreatment, and neglect. Whereas these factors, in the aggregate, explain a significant proportion of emotional and cognitive problems, there are serious gaps in our ability to identify potential mechanisms by which early life adversities might promote vulnerability or resilience. Here we discuss early life exposure to unpredictable signals from the caretaker as an understudied type of adversity that is amenable to prevention and intervention. We employ a translational approach …


Effects Of Early‑Life Experience On Innovation And Problem‑Solving In Captive Coyotes, Andrew C. Garcia, Mitchell A. Parsons, Julie K. Young Sep 2022

Effects Of Early‑Life Experience On Innovation And Problem‑Solving In Captive Coyotes, Andrew C. Garcia, Mitchell A. Parsons, Julie K. Young

USDA Wildlife Services: Staff Publications

Early-life experience often shapes behaviors like innovation and exploration. These behaviors are important to animals encountering novel food resources in diverse habitats, such as mesocarnivores in urban areas. To understand if early-life experiences impact later-life behavior, we examined how coyotes (Canis latrans) responded to a multi-access puzzle box at two life stages: pup (~ 7 weeks) and dispersal (~ 10 months). We first exposed pups, still living with their parents and littermates, to a baited puzzle box. At dispersal age, we again tested both these pups and an age-matched control group that was not exposed to the puzzle …


Creating And Implementing A Principal Investigator Tool Kit For Enhancing Accrual To Late Phase Clinical Trials: Development And Usability Study., Kristin A Higgins, Alexandra Thomas, Nancy Soto, Rebecca Paulus, Thomas J George, Thomas B Julian, Sharon Hartson Stine, Merry Jennifer Markham, Maria Werner-Wasik Aug 2022

Creating And Implementing A Principal Investigator Tool Kit For Enhancing Accrual To Late Phase Clinical Trials: Development And Usability Study., Kristin A Higgins, Alexandra Thomas, Nancy Soto, Rebecca Paulus, Thomas J George, Thomas B Julian, Sharon Hartson Stine, Merry Jennifer Markham, Maria Werner-Wasik

Kimmel Cancer Center Faculty Papers

BACKGROUND: Accrual to oncology clinical trials remains a challenge, particularly during the COVID-19 pandemic. For late phase clinical trials funded by the National Cancer Institute, the development of these research protocols is a resource-intensive process; however, mechanisms to optimize patient accrual after trial activation are underdeveloped across the National Clinical Trial Network (NCTN). Low patient accrual can lead to the premature closure of clinical trials and can ultimately delay the availability of new, potentially life-saving therapies in oncology.

OBJECTIVE: The purpose of this study is to formally create an easily implemented tool kit of resources for investigators of oncology clinical …


Effect Of Orthodontics On Upper Airway. Series 1: Growth And Development Of Airway, Kuang-Hsuan Chang, Eddie Hsiang-Hua Lai, Kang-Yee Wang, Hui-Jen Tsai, Chih-Liang Julian Ho Aug 2022

Effect Of Orthodontics On Upper Airway. Series 1: Growth And Development Of Airway, Kuang-Hsuan Chang, Eddie Hsiang-Hua Lai, Kang-Yee Wang, Hui-Jen Tsai, Chih-Liang Julian Ho

Taiwanese Journal of Orthodontics

Comprehensive treatment of the facial skeleton and occlusion requires an understanding of all functional variables, including the upper airway. Numerous reports have shown a causal relationship between the upper airway and respiratory mode in the development of facial morphology and malocclusion. This article reviewed the airway assessment in normal subjects during growth and development, obstructive sleep apnea (OSA) subjects and malocclusion subjects.


Development Of Wefit Screening Tool For Assessing Pre-Exercise Fitness Level For Older Adults In Peninsular Malaysia, Divya Vanoh, Arimi Fitri Mat Ludin, Suzana Shahar, Shahrul Azman Mohd Noah, Zahara Abdul Manaf, Noorlaili Mohd Tohit Aug 2022

Development Of Wefit Screening Tool For Assessing Pre-Exercise Fitness Level For Older Adults In Peninsular Malaysia, Divya Vanoh, Arimi Fitri Mat Ludin, Suzana Shahar, Shahrul Azman Mohd Noah, Zahara Abdul Manaf, Noorlaili Mohd Tohit

Journal of Health Research

Background: Pre-exercise screening is important to identify the fitness level of older adults prior to performing exercise. This study aimed to develop a screening tool for identifying older adults with poor physical fitness prior to exercising.

Method: Participants involved 2315 older adults from four states in Peninsular Malaysia. Several social and health parameters were investigated, and fitness level was assessed using hand grip strength. Receiver operating curve (ROC) analysis was chosen to determine the cut-off point, sensitivity, specificity, positive predictive value (PPV) and Youden`s Index of the screening tool.

Results: Age, sex, waist circumference, hypertension, diabetes mellitus and fasting blood …


On The Roles Of Trait Anxiety And Toll Like Receptor 4 In Amphetamine Sensitization In Adolescent Male Rats, Corey A. Calhoun May 2022

On The Roles Of Trait Anxiety And Toll Like Receptor 4 In Amphetamine Sensitization In Adolescent Male Rats, Corey A. Calhoun

Graduate Doctoral Dissertations

Mammalian adolescence can be a difficult transition from childhood to adulthood, where increases in impulsivity and novelty- and risk-seeking are combined with heightened affect and elevated sensitivity to stress. Indeed, during adolescence, first drug use patterns emerge and in the continental United States, increasing misuse of amphetamines has been observed in adolescent youth. Myriad neural mechanisms underlie this shift in adolescence, including the dynamic remodeling of the mesocorticolimbic (MCL) pathway. Repeated drug administration affects neuroimmune substrates within the MCL circuit including toll-like receptor 4 (TLR4)Advances in addiction neuroscience indicate that drugs of abuse activate neural TLR4 and implicate glial TLR4 …