Digital Commons Network^™

Differentiation Processes İn Late Cretaceous Ultrapotassic Volcanics Around Amasya, Fatma Gülmez, Ş. Can Genç

Bulletin of the Mineral Research and Exploration

Late Cretaceous lithologies around Amasya region are represented by Pontide fore-arc basin units which corresponds a volcanoclastic sequence. This sequence has the products of alkaline ultrapotassic magmatism accompanying calcalkaline lavas which are abundant along Pontide arc. The ultrapotassic rocks which are classified as leucitite, minette and trachyte based on their mineralogical composition, occur as dikes, stocks and rarely lava flows as to be comprised by the Late Cretaceous Volcanoclastic Succession (LCVS). Fractional crytallization accompanied by assimilation (AFC) is a low pressure processes able to differentiate ultrapotassic parental melts to various compositions in a continental margin tectonic setting.The trachytes are the …

Biodegradable Hybrid Nanogels For Combination Chemotherapy, Swapnil Desale

Theses & Dissertations

Combination chemotherapy is commonly used to treat cancer, because such a therapy regimens usually involve sequential administration of multiple drugs and allow targeting different cell signaling pathway. The co-delivery of drug combination at a controlled ratio via the same vehicle is offering the advantages such as spatial-temporal synchronization of drug exposure, synergistic therapeutic effects and suppression of drug resistance. Undoubtedly, there are several molecular and pharmacological factors that determine the effectiveness of drug combinations. A rationally designed drug combination is required since certain drug ratios and the definitive exposure to the targets of interest can only be synergistic while others …

Mole Street Journal, December 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Studying Nanoparticle/Cell And Nanoparticle/Biosurface Interaction With Mass Spectrometry, Singyuk Hou

Masters Theses

Nanoparticles (NPs) have been used widely in various fields ranging from biomedical applications to life science due to their highly tunable properties. It is essential to understanding how NPs interact with biological systems of interest, therefore, analytical platforms to efficiently track NPs from cell to animal level are essential. In this thesis, laser desorption ionization mass spectrometry (LDI-MS) and inductively-coupled plasma mass spectrometry (ICP-MS) has been developed and applied to quantify NP/cell and NP/biological surface interactions. These two methods provide fast, label-free and quantitative analysis. New capability of LDI-MS to differentiate cell surface-bound and internalized NPs were established and ICP-MS …

Mole Street Journal, October 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Joseph L. Ryan, Sj, Collection, New England Jesuit Province Archives, New England Province Of The Society Of Jesus, Joseph L. Ryan Sj

Finding Aids, Special Collections

All physical materials associated with the New England Province Archive are currently held by the Jesuit Archives in St. Louis, MO. Any inquiries about these materials should be directed to Jesuit Archives. Electronic versions of some items and the descriptions and finding aids to the Archives, which are hosted in CrossWorks, are provided only as a courtesy.

Joseph L. Ryan was born on December 4, 1920 in Brighton,MA, the son of John R. Ryan and Mary Ann (Connelly) Ryan. He was educated at Boston Latin School and Boston College High School, graduating in 1938. He entered into the Society …

Characterization And Target Identification Of Non-Toxic Ikkβ Inhibitors For Anticancer Therapy, Elizabeth Blowers

Theses & Dissertations

IKKβ is a key kinase in the canonical NF-κB pathway. Transient activation of IKKβ is required for normal immune response while sustained activation has been implicated in cancer. To date, no IKKβ inhibitor has been approved for clinical use as a chemotherapeutic, likely due to unexpected toxicities associated with blocking the transient activation of IKKβ. We hypothesized that an IKKβ inhibitor that allows transient activation of IKKβ, but not sustained activation of IKKβ, could inhibit cancer growth without inducing toxicity.

As such, we identified a small molecule inhibitor, 13-197, that allows the transient activation of IKKβ but not the sustained …

Experimental And Ab Initio Computational Study Of Azobenzene And Several Of Its Derivatives, Mohammadreza Rezaee

Doctoral Dissertations

In this dissertation we studied azobenzene and seven of its derivatives experimentally in addition to comprehensive ab initio computational investigation. Gas phase ion chemistry studies sre a rich and important area of chemical physics. We used an energy resolved collision induced dissociation technique to study the chemical bonding of these molecule negative or positive ions. We studied the fragment ions which we have detected in the mass spectrum computationally as well. Doing so we experimentally measured the bond dissociation energies and compared them with those resulting from the quantum chemistry computations. We also performed other experiments such as Raman spectroscopy, …

Mole Street Journal, August 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Polygon Distances With Applications To High Performance Liquid Chromatography, Vito Capuano

All Theses

Analytical chemistry uses high performance liquid chromatography (HPLC) to separate desired macromolecules from a fluid. This thesis is concerned with monolithic column environments used in HPLC separations. The monolithic column environment under consideration consists of many long polymer fibers suspended in a tube. Between the fibers are voids (interstices) which regulate the separation process. The goal of this thesis is both to identify interstices of a size such that the interstice contributes to the separation process, and to identify the boundaries of the fibers along such interstices. We model the cross section of the column environment with a collection of …

Development Of A Stereochemistry Concept Inventory, Alexey Leontyev

Dissertations

No abstract provided.

Matching Watershed And Otolith Chemistry To Establish Natal Origin Of An Endangered Desert Lake Sucker, Deanna Strohm

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Like many native endemic desert freshwater fish species, the June Sucker (Chasmistes liorus) is currently listed as endangered. Managers have increasingly turned to habitat restoration as a key component to recovery plans. For endangered species, one of the primary outcomes of habitat restoration is that it should result in successful reproduction and recruitment of individuals into the adult population. Confirmation of natural recruitment as a function of habitat restoration can only be achieved by establishing natal origins.

Recent research has proven the validity of otolith microchemistry, a technique that analyzes small quantities of elements, to trace potamodromous fish …

Electrode And Electrolyte Materials For Batteries, Shiou-Jyh Hwu, Gregory A. Becht

Clemson Patents

Disclosed are open-framework solids that possess superior ion-transport properties pertinent to the electrochemical performance of next-generation electrode materials for battery devices. Disclosed compounds including compositions and architectures relevant to electrical energy storage device applications have been developed through integrated solid-state and soft (solution) chemistry studies. The solids can adopt a general formula of A.sub.xM.sub.y(XO.sub.4).sub.z, where A=mono- or divalent electropositive cations (e.g., Li.sup.+), M--trivalent transition metal cations (e.g., Fe.sup.3+, Mn.sup.3+), and X.dbd.Si, P, As, or V. Also disclosed are oxo analogs of these materials having the general formulae A.sub.aM.sub.bO.sub.c(PO.sub.4).sub.d (a.gtoreq.b), and more specifically, A.sub.nM.sub.nO.sub.3x(PO.sub.4).sub.n-2x, where A=mono- or divalent electropositive cations (e.g., …

Strategic Partnerships For New Perspectives On Teaching Information Literacy To Students Of Industrial Engineering And Management, Simone Kibler

Proceedings of the IATUL Conferences

No abstract provided.

2015-2016 Undergraduate Bulletin, University Of Puget Sound

University of Puget Sound Bulletins

No abstract provided.

Monitoring The Progression Of Spontaneous Articular Cartilage Healing With Infrared Spectroscopy, Megan P. O'Brien, Madhuri Penmatsa, Uday Palukuru, Paul West, Xu Yang, Mathias P. G. Bostrom, Theresa Freeman, Nancy Pleshko

Publications and Research

Objective. Evaluation of early compositional changes in healing articular cartilage is critical for understanding tissue repair and for therapeutic decision-making. Fourier transform infrared imaging spectroscopy (FT-IRIS) can be used to assess the molecular composition of harvested repair tissue. Furthermore, use of an infrared fiber-optic probe (IFOP) has the potential for translation to a clinical setting to provide molecular information in situ. In the current study, we determined the feasibility of IFOP assessment of cartilage repair tissue in a rabbit model, and assessed correlations with gold-standard histology.

Design. Bilateral osteochondral defects were generated in mature white New Zealand rabbits, and …

Infrared Investigations Of The Composition And Structure Of Nearby Protoplanetary Disks, Valerie Ann Rapson

Theses

Near- to far-infrared imaging and spectroscopy of nearby (pc), low mass pre-main sequence stars that are orbited by gaseous and dusty circumstellar disks allow astronomers to probe the chemical composition and structure of protoplanetary disks, and further understand disk evolution and planet formation processes. In this dissertation, I present an infrared imaging and spectral analysis of the young star-disk systems V4046 Sgr, T Cha and MP Mus. V4046 Sgr is a nearby (D~73 pc), ~20 Myr-old spectroscopic binary surrounded by a large (R~350 AU) circumbinary disk. T Cha and MP Mus are similarly nearby (Dpc) and young (old) single-star systems …

Crustal And Upper Mantle Structure Beneath The Northeastern Tibetan Plateau From Joint Analysis Of Receiver Functions And Rayleigh Wave Dispersions, Dan Zheng, Hongyi Li, Yang Shen, Jing Tan, Longbin Ouyang, Xinfu Lu

Graduate School of Oceanography Faculty Publications

The crustal and upper mantle velocity structure in the northeastern Tibetan Plateau is obtained from joint analysis of receiver functions and Rayleigh wave dispersions. The resulting velocity model reveals a close correlation between the thick (>60 km) crust and the presence of an intracrustal low-velocity zone beneath the Qiangtang and Songpan-Ganzi terranes as well as the northwestern Qilian orogen. However, the high V_p/V_s ratio of the crust is found only beneath the Qiangtang and Songpan-Ganzi terranes. The crustal low velocity zone does not appear in the west Qinling and southeastern Qilian orogens, which have a …

Mole Street Journal, June 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Using Otolith Microchemistry To Classify Yellow Perch As Stocked Or Naturally Produced, Andrew K. Carlson, Matthew J. Ward, Brian D.S Graeb

The Prairie Naturalist

Fisheries managers routinely use stocking to supplement fish populations (Schramm and Piper 1995, Fisher 1996). Stocking eyed-eggs offers substantial cost savings compared to stocking fry and fingerlings (PFBC 2011); however, traditional stocking evaluation using oxytetracycline (OTC) marking of otoliths is ineffective for eyed-eggs of some species (e.g., yellow perch, [Perca fla- vescens]). Thus, there is a need for additional approaches to be able to classify fish as stocked or naturally produced. Fish otoliths are paired calcified structures in the inner ear that permanently deposit trace elements in proportion to water column concentrations (Campana 1999, Campana et al. 2000). Coupled with …

Fluorescent Cell Imaging Studies Of Antitumor Natural Macrocycle Ipomoeassin F, Margaret Grace Oliver

Biological Sciences Undergraduate Honors Theses

Ipomoeassin F is one member of a family of macromolecules isolated from the leaves of the morning glory flower, ipomoea squamosa, which has been used as a homeopathic cancer remedy for centuries (Zhu, Huang, Zheng, Zhu, & Yang, 2013). It has been proven to be highly cytotoxic to many cancer cell lines, but nothing is yet known of its mode of action in the cell (Cao, et al., 2007). To begin progress towards understanding the mode of action of ipomeoassin F, this study aimed to perform fluorescence imaging studies for the ultimate purpose of determining its cellular localization in MDA-MB-231 …

Studies Of The Preparation Of Pi-Extended Anthracenes And Their Reactivity With An Emphasis On Their Photoreactivity, Hasnaa Abdelkareem Sadeq

Theses

Both 9,10-diaryl and 9,10-diarylethenyl substituted Anthracenes have recently been forwarded as light-regulated semiconducting materials, as well as potential constituent molecules in light-harvesting devices for the organic solar cell applications. So, it is of importance to understand whether such 9,10-substituted Anthracenes are stable under photo-irradiation for a long time, and what type of reactions they could undergo. In the present thesis, photochemistry of 9-anthranylacrylates and 9-aroylethenylanthracenes has been investigated. Anthranylacrylates and 9-aroylethenylanthracenes have been prepared by Wittig-olefination reaction from 9-anthranylcarbaldehyde. Bromination of these molecules was found to give an access to 10-aryl-9-aroylethenylanthracenes after Suzuki-Miyaura coupling reactions. While 9-ethenyl-substituted Anthracenes in principle …

Rate Coefficients For H+No2→Oh+No From High Pressure Flow Reactor Experiments, Francis M. Haas, Frederick L. Dryer

Francis (Mac) Haas

Osteology Of A Burial Vessel From The Late Prehistoric/Early Contact Period Pine Harbor Site (9mc64), Amanda C. Shively

Honors College Theses

This research focuses on osteological examination of a single urn-burial’s contents from Pine Harbor (9MC64), a late prehistoric to early contact period archaeological site excavated on the coast of Georgia in 1978. Analysis generated from this study seeks to shed light on burial demographics and practices of its native occupants.

Mole Street Journal, April 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Voltammetric Investigation Of Xanthate Chemisorption On A Chalcopyrite Surface, Jesse Lynn Bowden

Graduate Theses & Non-Theses

Cyclic Voltammetry experiments have been conducted on copper, iron, and chalcopyrite (CuFeS2) and compared to mass-balanced EH-pH Diagrams. Potassium ethyl xanthate (KEX) was added to solution and additional voltammetry experiments were performed to determine the surface chemistry reactions of flotation collector in solution with these minerals. The ultimate goal of this research was to investigate the possibility of xanthate chemisorption onto the chalcopyrite mineral surface. Results of the copper mineral testing confirm previous literature studies and corroborate published isotherm data. Results of the iron mineral testing showed changes in surface reactions with the addition of potassium ethyl xanthate to solution, …

Regional Patterns In The Otolith Chemistry Of Juvenile Spotted Seatrout (Cynoscion Nebulosus) Differ Under Contrasting Hydrological Regimes, Chet F. Rakocinski, Bruce H. Comyns, Mark S. Peterson, Alan M. Shiller

Faculty Publications

The value of using otolith chemistry to characterize recruitment in terms of natal source regions depends on how consistently spatio-temporal variation can be resolved. The objective of this study was to compare regional classification patterns in the otolith chemistry of juvenile Spotted Seatrout (Cynoscion nebulosus) between two years experiencing disparate hydrological regimes, and separated by a five year interlude. Spatial patterns in the whole-otolith chemistry of juveniles of this estuarine-dependent species were compared between years using five otolith elements and two stable isotopes. Consistent size-related trends in uptake and deposition were evidenced by parallel ontogenetic relationships for six otolith variables. …

Mole Street Journal, February 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Molecular Modeling Of Sigma 1 And Sigma 2 Receptor Ligands: Pharmacophore Development And Comparison Using Discotech And Bioactivity Prediction Comparison Of Ab Initio And Density Functional Comfa Studies For Spiro And Other Receptor Ligands, Lisa M. Kardos

Dissertations

The role of the biological receptor is currently being studied by researchers in medicine. Information about sigma receptors in particular can be gained by studying the ligands associated with each type, sigma 1 or sigma 2. Sigma 1 receptor ligands consist of drug candidates that often have psychiatric and neurological applications; sigma 2 receptor ligands consist of drug candidates that have been linked with cancer treatment among other applications.

Molecular modeling of biological receptor ligands often encompasses pharmacophore development and Comparative Molecular Field Analysis (CoMFA). Pharmacophore models are developed to understand the unique features such as binding groups that make …

A Comparative Study Of The Oxidation Characteristics Of Two Gasoline Fuels And An N-Heptane/Iso-Octane Surrogate Mixture, Tamour Javed, Ehson F. Nasir, Et-Touhami Es-Sebbar, Aamir Farooq

Dr. Et-touhami Es-sebbar

Ignition delay times and CO, H2O, OH and CO2 time-histories were measured behind reflected shock waves for two FACE (Fuels for Advanced Combustion Engines) gasolines and one PRF (Primary Reference Fuel) blend. The FACE gasolines chosen for this work are primarily paraffinic and have the same octane rating (∼RON = 84) as the PRF blend, but contain varying amounts of iso- and n-paraffins. Species time-histories and ignition delay times were measured using laser absorption methods over a temperature range of 1350–1550 K and pressures near 2 atm. Measured species time-histories and ignition delay times of the PRF blend and the …