Digital Commons Network^™

Optimization Of A Hardware/Software Coprocessing Platform For Eeg Eyeblink Detection And Removal, Matthew Alan Chaudhuri

Theses

The feasibility of implementing a real-time system for removing eyeblink artifacts from electroencephalogram (EEG) recordings utilizing a hardware/software coprocessing platform was investigated. A software based wavelet and independent component analysis (ICA) eyeblink detection and removal process was extended to enable variation in its processing parameters. Exploiting the efficiency of hardware and the reconfigurability of software, it was ported to a field programmable gate array (FPGA) development platform which was found to be capable of implementing the revised algorithm, although not in real-time. The implemented hardware and software solution was applied to a collection of both simulated and clinically acquired EEG …

Tnfα Sirna Reduces Brain Tnf And Eeg Delta Wave Activity In Rats, Ping Taishi, Lynn Churchill, Mingxiang Wang, Daniel Kay, Christopher J. Davis, Xin Guan, Alok De, Tadanobu Yasuda, Fan Liao, James M. Krueger

Faculty Publications

Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine with several CNS physiological and pathophysiological actions including sleep, memory, thermal and appetite regulation. Short interfering RNAs (siRNA) targeting TNFα were incubated with cortical cell cultures and microinjected into the primary somatosensory cortex (SSctx) of rats. The TNFα siRNA treatment specifically reduced TNFα mRNA by 45% in vitro without affecting interleukin-6 or gluR1-4 mRNA levels. In vivo the TNFα siRNAα reduced TNFα mRNA, interleukin-6 mRNA and gluR1 mRNA levels compared to treatment with a scrambled control siRNA. After in vivo microinjection, the density of TNFα-immunoreactive cells in layer V of the …

Bio-Signal Analysis In Fatigue And Cancer Related Fatigue;Weakening Of Corticomuscular Functional Coupling, Qi Yang

ETD Archive

Fatigue is a common experience that reduces productivity and increases chance of injury, and has been reported as one of most common symptoms with greatest impact on quality-of-life parameters in cancer patients. Neural mechanisms behind fatigue and cancer related fatigue (CRF) are not well known. Recent research has shown dissociation between changes in brain and muscle signals during voluntary muscle fatigue, which may suggest weakening of functional corticomuscular coupling (fCMC). However, this weakening of brain-muscle coupling has never been directly evaluated. More important information could be gained if fCMC is directly detected during fatigue because a voluntary muscle contraction depends …

The Relationships Among Age, Physical Activity, And Working Memory, Ellen M. Carpenter

Psychology Theses & Dissertations

As our population ages, determining exogenous factors that may offset cognitive decline become increasingly important. The primary goal of the present study was to determine whether older individuals who engage in regular physical activity demonstrate superior working memory performance relative to older sedentary individuals. Forty young (20 active, 20 sedentary) and forty older (20 active, 20 sedentary) individuals engaged in cognitive measures of information processing speed, inhibitory function, and verbal and visuospatial working memory. Age differences in recall were found for verbal and visuospatial span tasks, as well as for recall reaction time on verbal and visuospatial n-back tasks, and …

Comparison Of Basic Linear Filters In Extracting Auditory Evoked Potentials, Serap Aydin

Turkish Journal of Electrical Engineering and Computer Sciences

In the present study, the performances of two well-known linear filtering techniques are compared for extraction of auditory Evoked Potential (EP) from a relatively small number of sweeps. Both experimental and simulated data are filtered by the two algorithms into two groups. Group A consists of Wiener filtering (WF) applications, where conventional WF and Coherence Weighted WF (CWWF)) have been assessed in combination with the Subspace Method (SM). Group B consists of the well-known adaptive filtering algorithms Least Mean Square (LMS), Recursive Least Square (RLS), and one-step Kalman filtering (KF). Both groups are tested with respect to signal-to-noise ratio (SNR) …

Examining Audiovisual Integration Of Visually Presented Letters And Their Auditory Letter Names Using Electroencephalography (Eeg), Allison J.D. Andres

Digitized Theses

Audiovisual integration is an important process in human perception. However, it is

unclear whether auditory and visual stimuli are integrated during primary sensory processing, or following independent processing in their respective sensory cortices. This study examined 16 adult participants’ responses to simultaneously presented congruent and incongruent visual letters and auditory letter names using electroencephalography (EEG). Auditorystimuliwerepresentedinanunattendedoddballparadigm,usingthe mismatch negativity (MMN) event-related potential (ERP) component as an indicator of primary auditory processing. Participants also identified whether or not visual letters were vowels using a key press. No difference was found in the MMN across congruent and incongruent triais. However, differences in the …