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2008

Cannabis

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Interface Of Cannabis And Early Psychosis--Priorities In Research And Service Development, Amresh Srivastava Oct 2008

Interface Of Cannabis And Early Psychosis--Priorities In Research And Service Development, Amresh Srivastava

Psychiatry Presentations

Introduction: cannabis continues to affect mental health. Its abuse is on rise globally. In Canada a rise by 30% in last ten years has been observed in high school students. Interrelationship of cannabis with psychosis and schizophrenia is a complex one. Cannabis is highly comorbid with psychosis, & related to functional disability and outcome. It poses several challenges in understanding causal relationship for comorbidity, underlying neurochemical basis and specifics of service development. Prevalence of Cannabis varies from 20 to 50% early psychosis. Objective of this paper is to review available literature to identify challenges for newer targets of research and …

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Cannabis & Psychosis: The Interface Emerging Frontiers For Research, Amresh Shrivastava Oct 2008

Cannabis & Psychosis: The Interface Emerging Frontiers For Research, Amresh Shrivastava

Psychiatry Presentations

INTRODUCTION: CANNABIS CONTINUES TO AFFECT MENTAL HEALTH. ITS ABUSE IS ON RISE GLOBALLY. IN CANADA A RISE BY 30% IN LAST TEN YEARS HAS BEEN OBSERVED IN HIGH SCHOOL STUDENTS. INTERRELATIONSHIP OF CANNABIS WITH PSYCHOSIS AND SCHIZOPHRENIA IS A COMPLEX ONE. CANNABIS IS HIGHLY COMORBID WITH PSYCHOSIS, & RELATED TO FUNCTIONAL DISABILITY AND OUTCOME. IT POSES SEVERAL CHALLENGES IN UNDERSTANDING CAUSAL RELATIONSHIP FOR COMORBIDITY, UNDERLYING NEUROCHEMICAL BASIS AND SPECIFICS OF SERVICE DEVELOPMENT. PREVALENCE OF CANNABIS VARIES FROM 20 TO 50% EARLY PSYCHOSIS. OBJECTIVE OF THIS PAPER IS TO REVIEW AVAILABLE LITERATURE TO IDENTIFY CHALLENGES FOR NEWER TARGETS OF RESEARCH AND …

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Analysis Of Residue In Pipes That Were Smoked By Prehistoric North American Indians In The States And Portions Of Canada East Of The Mississippi, Tommy Charles Aug 2008

Analysis Of Residue In Pipes That Were Smoked By Prehistoric North American Indians In The States And Portions Of Canada East Of The Mississippi, Tommy Charles

Faculty & Staff Publications

No abstract provided.

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Personality And Cannabis Use, Emma Barkus Jan 2008

Personality And Cannabis Use, Emma Barkus

Faculty of Health and Behavioural Sciences - Papers (Archive)

Cannabis is one of the most widely used illegal substances in the world. Its use has been reported to be over-represented in many psychiatric conditions and has frequently been found to predate the onset of psychiatric symptoms. However, cannabis may also have detrimental effects on the general population. Factors that predict the onset of use are receiving increased attention to aid in identifying groups of young people who may be more prone to consume cannabis. Personality traits may be one such factor as they are readily identifiable and offer information that can be used for improved targeting of educational material …

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Cannabis-Induced Psychotic-Like Experiences Are Predicted By High Schizotypy. Confirmation Of Preliminary Results In A Large Cohort., John Stirling, Emma Barkus, L Nabosi, S Irshad, G Roemer, B Schreudergoidheijt, Shon Lewis Jan 2008

Cannabis-Induced Psychotic-Like Experiences Are Predicted By High Schizotypy. Confirmation Of Preliminary Results In A Large Cohort., John Stirling, Emma Barkus, L Nabosi, S Irshad, G Roemer, B Schreudergoidheijt, Shon Lewis

Faculty of Health and Behavioural Sciences - Papers (Archive)

Background: Cannabis use has been identified as a possible risk factor for developing schizophrenia. In a previous paper we reported preliminary evidence that cannabis use increases the likelihood of psychosis-like experiences in non-clinical respondents who scored highly on a measure of schizotypy. We now present findings from pooled data from 3 new follow-up studies comprising a sample of 477 respondents, of whom 332 reported using cannabis at least once. Sampling and Methods: As in our previous study, the psychological effects of cannabis were assessed with the Cannabis Experiences Questionnaire, from which 3 subscales can be derived; encompassing pleasurable experiences, psychosis-like …

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Visuospatial Memory Deficits In Long Term Heavy Cannabis Users: Relation To Psychotic Symptoms And Regional Brain Volumes, Nadia Solowij, Colleen Respondek, Robert A. Battisti, Sarah Whittle, Daniel Dr Daniel Lubman, Murat Yucel Jan 2008

Visuospatial Memory Deficits In Long Term Heavy Cannabis Users: Relation To Psychotic Symptoms And Regional Brain Volumes, Nadia Solowij, Colleen Respondek, Robert A. Battisti, Sarah Whittle, Daniel Dr Daniel Lubman, Murat Yucel

Faculty of Social Sciences - Papers (Archive)

Abstract from the XXVI CINP Congress, Munich, 13-17 July 2008

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Cannabinoid Modulation Of Microglial Activation In Multiple Sclerosis, Natalie Shea Lemons Jan 2008

Cannabinoid Modulation Of Microglial Activation In Multiple Sclerosis, Natalie Shea Lemons

Honors Theses

Multiple Sclerosis (MS) is a neurodegenerative disease that is estimated to affect 400,000 Americans. There is no cure for MS and some treatments at this point are toxic to patients. Dr. Lori Hensley's lab is researching two drugs that could potentially be used to treat MS without toxic effects. Previous work in the lab shows ajulemic acid, a synthetic molecule similar to metabolites from the cannabis plant, selectively suppresses markers of the inflammatory response. worked on the mechanism of ajulemic acid's action by investigating the roles of several candidate receptors in mediating these observed effects.

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Schizotypy And Psychosis-Like Experiences From Recreational Cannabis In A Non-Clinical Sample, Emma Barkus, Shon Lewis Jan 2008

Schizotypy And Psychosis-Like Experiences From Recreational Cannabis In A Non-Clinical Sample, Emma Barkus, Shon Lewis

Faculty of Health and Behavioural Sciences - Papers (Archive)

Background. The relationship between cannabis use and psychosis is still a matter for debate. Accounting for the individual differences in subjective experiences to recreational cannabis use in the general population may hold some clues to the aetiological relationship between cannabis and psychotic symptoms. We hypothesized that schizotypy would account for the individual differences in subjective experiences after cannabis use but not in patterns of use. Method. In a sample of 532 young people who had used cannabis at least once, we examined the relationship between the Cannabis Experiences Questionnaire (CEQ) and the Schizotypal Personality Questionnaire (SPQ). Additionally, we examined the …

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