Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Physical Sciences and Mathematics (16)
- Chemistry (11)
- Life Sciences (5)
- Computer Sciences (2)
- Engineering (2)
-
- Social and Behavioral Sciences (2)
- Software Engineering (2)
- Biochemistry (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Business (1)
- Human Resources Management (1)
- Materials Science and Engineering (1)
- Medicinal-Pharmaceutical Chemistry (1)
- Medicine and Health Sciences (1)
- Organic Chemistry (1)
- Other Chemistry (1)
- Physiology (1)
- Programming Languages and Compilers (1)
- Institution
-
- TÜBİTAK (6)
- University of Wollongong (4)
- Virginia Commonwealth University (2)
- Bowling Green State University (1)
- Brigham Young University (1)
-
- California Polytechnic State University, San Luis Obispo (1)
- Louisiana State University (1)
- Rochester Institute of Technology (1)
- Singapore Management University (1)
- Technological University Dublin (1)
- University of Central Florida (1)
- University of Lynchburg (1)
- University of Massachusetts Amherst (1)
- University of Windsor (1)
- Western Kentucky University (1)
- Publication
-
- Turkish Journal of Chemistry (6)
- Theses and Dissertations (3)
- Electronic Theses and Dissertations (2)
- Faculty of Science - Papers (Archive) (2)
- Australian Institute for Innovative Materials - Papers (1)
-
- Chemistry Faculty Publications (1)
- Collaborative Agent Design (CAD) Research Center (1)
- Computer Science Department Faculty Publication Series (1)
- Illawarra Health and Medical Research Institute (1)
- LSU Doctoral Dissertations (1)
- Mahurin Honors College Capstone Experience/Thesis Projects (1)
- Masters (1)
- Research Collection School Of Computing and Information Systems (1)
- Theses (1)
- Undergraduate Theses and Capstone Projects (1)
- Publication Type
Articles 1 - 24 of 24
Full-Text Articles in Entire DC Network
Advancing The Methodology For Cyclopenta[C]Thiophene Sythesis: A Step Toward Anit-Leukemia Agents And Improved Semiconductiors, Riley Jones
Mahurin Honors College Capstone Experience/Thesis Projects
Metal n5-cyclopenta[c]thienyl complexes are of significant interest in both catalysis and materials chemistry. These relatives of the low-band-gap polymer polybenzo[2,3-c]thiophene show great promise as environmentally stable conductive polymers and as energy-efficient light-emitting diodes (LEDs) due to their unique electronic properties. Recently, studies have shown that cyclopenta[c]thiophene molecules are effective as photodynamic anticancer agents which are particularly aggressive toward leukemia cells. The current method of synthesizing these compounds is lengthy, costly, and has a very low yield. Our group has developed a novel one-step method to produce precursors of these compounds. This procedure increases product yields, eliminates the use of toxic …
Elements Of Human Decision-Making, Jens G. Pohl
Elements Of Human Decision-Making, Jens G. Pohl
Collaborative Agent Design (CAD) Research Center
The purpose of this paper is to present some understandings of the human problem-solving activity that we have gained in the Collaborative Agent Design Research Center (CADRC) over the past two decades. Since we feel strongly that the human decision-maker should be an integral component of any computer-based decision-support system, it follows that we would have endeavored to incorporate many of the elements that appear to be important to the user in the design of these systems. The complexity of the human cognitive system is evidenced by the large body of literature that describes problem-solving behavior and the relatively fewer …
Structure-Activity Studies Of Glycosphingolipids As Antigens Of Natural Killer T Cells, Randal Donald Goff
Structure-Activity Studies Of Glycosphingolipids As Antigens Of Natural Killer T Cells, Randal Donald Goff
Theses and Dissertations
Glycosphingolipids (GSLs), composed of a polar saccharide head and a lipophilic ceramide tail, are ubiquitous components of the plasma membrane of eukaryotic cells. They serve in many regulatory capacities and have antigenic properties towards natural killer T (NKT) cells of the innate immune system. Critical to the recognition of glycosylceramides by NKT cells are antigen presenting cells (APC), such as dendritic cells, which are responsible for binding, processing, and delivery of ligands to these lymphocytes. This event is mediated by CD1d, a major histocompatibility complex-like protein expressed on the surface of APCs, which binds GSL antigens by the ceramide moiety …
The Synthesis Of Zinc Oxide By Direct And Indirect Methods, Grainne Duffy
The Synthesis Of Zinc Oxide By Direct And Indirect Methods, Grainne Duffy
Masters
The synthesis of zinc oxide through three routes was investigated; carboxylic acid chelation, polymer assisted synthesis in an alcoholic medium and slow thermolysis of precursor. In the case of carboxylic acid chelation, it was determined that the rate at which the precursor is formed has a significant effect on the quality of zinc oxide particles produced. Investigation of the effect of concentration, pH and species of chelating agent used on the purity and structure of product was undertaken. Examination of the composition and morphology of materials produced revealed the presence of single-crystalline spheres, the packing density and aggregation morphology of …
Synthesis Of Aspernigrin A, Erica Joerger
Synthesis Of Aspernigrin A, Erica Joerger
Undergraduate Theses and Capstone Projects
Aspernigrin A is a compound correlated with inhibiting the growth of cancer cells in the colon. A five-step synthesis was designed for aspernigrin A, projected to yield four intermediates and the final product. The intermediates were analyzed by high field 1HNMR and FT-IR spectroscopy before proceeding to the next step. A model pyridone ring system was successfully prepared from a commercially available pyrone precursor in two steps. These results provide a proof of concept that the synthetic scheme should successfully yield the natural product.
Synthesis Of Low K1 Projection Lithography Utilizing Interferometry, Frank Cropanese
Synthesis Of Low K1 Projection Lithography Utilizing Interferometry, Frank Cropanese
Theses
Interference lithography has been widely utilized as a tool for the evaluation of photoresist materials, as well as emerging resolution enhancement techniques. The interferometric approach is both simple and inexpensive to implement, however it is limited in its ability to examine the impact of defocus due to the inherently large DOF (Depth-of-Focus) in two-beam interference. Alternatively, the demodulation of the aerial image that occurs as a result of defocus in a projection system may be synthesized using a two pass exposure with the interferometric method. The simulated aerial image modulation for defocused projection systems has been used to calculate the …
1,3-Indane-Based Chromogenic Calixpyrroles With Push-Pull Chromophores: Synthesis And Anion Sensing, Ryuhei Nishiyabu, Pavel Anzenbacher Jr.
1,3-Indane-Based Chromogenic Calixpyrroles With Push-Pull Chromophores: Synthesis And Anion Sensing, Ryuhei Nishiyabu, Pavel Anzenbacher Jr.
Chemistry Faculty Publications
Knoevenagel condensation of 2-formyl-octamethylcalix[4]pyrrole with selected 1,3-indanedione derivatives yields calix[4]pyrrole anion sensors with push-pull chromophores displaying strong intramolecular charge transfer. The push-pull feature results in augmented signal output as well as in dramatic changes in anion selectivity exemplified by a 50-fold increase in acetate vs chloride selectivity compared to the parent calix[4]pyrrole.
Design Synthesis From Interaction And State-Based Specifications, Jun Sun, Jin Song Dong
Design Synthesis From Interaction And State-Based Specifications, Jun Sun, Jin Song Dong
Research Collection School Of Computing and Information Systems
Interaction-based and state-based modeling are two complementary approaches of behavior modeling. The former focuses on global interactions between system components. The latter concentrates on the internal states of individual components. Both approaches have been proven useful in practice. One challenging and important research objective is to combine the modeling power of both effectively and then use the combination as the basis for automatic design synthesis. We present a combination of interaction-based and state-based modeling, namely, Live Sequence Charts and Z, for system specification. We then propose a way of generating distributed design from the combinations. Our approach handles systems with …
Formation Of Magnesium Diboride-Based Materials With High Critical Currents And Mechanical Characteristics By High-Pressure Synthesis, Tetiana Prikhna, W. Gawalek, Ya M. Savchuk, N. V. Sergienko, V. E. Moshchil, M. Wendt, M. Zeisberger, T. Habisreuther, V. B. Sverdun, S X. Dou, S. N. Dub, V. S. Melnikov, Ch Schmidt, J. Dellith, P. A. Nagorny
Formation Of Magnesium Diboride-Based Materials With High Critical Currents And Mechanical Characteristics By High-Pressure Synthesis, Tetiana Prikhna, W. Gawalek, Ya M. Savchuk, N. V. Sergienko, V. E. Moshchil, M. Wendt, M. Zeisberger, T. Habisreuther, V. B. Sverdun, S X. Dou, S. N. Dub, V. S. Melnikov, Ch Schmidt, J. Dellith, P. A. Nagorny
Australian Institute for Innovative Materials - Papers
The developed method of high-pressure synthesis (HPS) allows producing nanostructural highly dense material based on MGB2, which possesses the highest superconducting and mechanical characteristics among the known world analogues, in the form of blocks that are suitable for application in SC electromotors and pumps. Additions of Zr can increase critical current density (jc) of synthesized at 2 GPa and 750-800 °C MGB2 in the same manner as additions of Ta or Ti, i.e. due to the absorption of impurity hydrogen forming the ZrH2. The formation of ZrB2 phase at higher synthesis …
Microwave-Assisted Facile Synthesis And Crystal Structure Of Cis-9,10,11,15-Tetrahydro-9,10[3'4']-Furanoanthracene-12,14-Dione, Weerachai Phutdhawong, Duang Buddhasukh, Stephen G. Pyne, Apinpus Rujiwatra, Chaveng Pakawatchai
Microwave-Assisted Facile Synthesis And Crystal Structure Of Cis-9,10,11,15-Tetrahydro-9,10[3'4']-Furanoanthracene-12,14-Dione, Weerachai Phutdhawong, Duang Buddhasukh, Stephen G. Pyne, Apinpus Rujiwatra, Chaveng Pakawatchai
Faculty of Science - Papers (Archive)
A facile synthesis and crystal structure of cis‐9,10,11,15‐tetrahydro‐9,10[3′,4′]‐furanoanthracene‐12,14‐dione from the reaction of anthracene and maleic anhydride in xylene in a short time and high yield using a modified commercial domestic microwave oven is reported.
Involvement Of Akt In Er-To-Golgi Transport Of Scap/Srebp: A Link Between A Key Cell Proliferative Pathway And Membrane Synthesis, X Du, Ika Kristiana, Jenny Wong, A Brown
Involvement Of Akt In Er-To-Golgi Transport Of Scap/Srebp: A Link Between A Key Cell Proliferative Pathway And Membrane Synthesis, X Du, Ika Kristiana, Jenny Wong, A Brown
Illawarra Health and Medical Research Institute
Akt is a critical regulator of cell growth, proliferation, and survival that is activated by phosphatidylinositol 3-kinase (PI3K). We investigated the effect of PI3K inhibition on activation of sterol regulatory element binding protein-2 (SREBP-2), a master regulator of cholesterol homeostasis. SREBP-2 processing increased in response to various cholesterol depletion approaches (including statin treatment) and this increase was blunted by treatment with a potent and specific inhibitor of PI3K, LY294002, or when a plasmid encoding a dominant-negative form of Akt (DN-Akt) was expressed. LY294002 also suppressed SREBP-2 processing induced by insulin-like growth factor-1. Furthermore, LY294002 treatment down-regulated SREBP-2 or -1c gene …
Asymmetric Synthesis Of Anti-1,2-Amino Alcohols Via The Borono-Mannich Reaction: A Formal Synthesis Of (-)-Swainsonine, Christopher W. G. Au, Stephen G. Pyne
Asymmetric Synthesis Of Anti-1,2-Amino Alcohols Via The Borono-Mannich Reaction: A Formal Synthesis Of (-)-Swainsonine, Christopher W. G. Au, Stephen G. Pyne
Faculty of Science - Papers (Archive)
Chiral α-hydroxy-aldehydes generated in situ by the ADH reaction of vinyl sulfones undergo a borono-Mannich reaction with β-styrenyl boronic acid and primary amines to give anti-1,2-amino alcohols in high enantiomeric purities (ee 83-95%). This new method allows much more rapid access to these valuable chiral building blocks that has been used in a short formal synthesis (10 synthetic steps from 4-penten-1-ol) of (-)-swainsonine.
Synthesis Of Novel Antimycobacterials And A Fluorescent Sensor For Simple Carbohydrates, Brian Thomas Walker
Synthesis Of Novel Antimycobacterials And A Fluorescent Sensor For Simple Carbohydrates, Brian Thomas Walker
Theses and Dissertations
Cell surface carbohydrates play an important role in a wide variety of biological processes such as inflammation, tumor metastasis, and viral and bacterial infection. The goal of our research has been two-fold. The first objective was the synthesis of antimycobacterial compounds. A mannose containing tetrasaccharide from the mannan core of lipoarabinomannan (LAM) of Mycobacterium tuberculosis has been synthesized using α-D-methylmannopyranoside as starting material and Koeings-Knorr reactions to couple saccharides. The synthesis was completed in nine steps and in 14% total yield. This compound should be useful in competitive inhibition studies with macrophages or as an immunological marker. We have successfully …
Synthesis, Processing And Characterization Of Nanocrystalline Titanium Dioxide, Shipeng Qiu
Synthesis, Processing And Characterization Of Nanocrystalline Titanium Dioxide, Shipeng Qiu
Electronic Theses and Dissertations
Titanium dioxide (TiO2), one of the basic ceramic materials, has found a variety of applications in industry and in our daily life. It has been shown that particle size reduction in this system, especially to nano regime, has the great potential to offer remarkable improvement in physical, mechanical, optical, biological and electrical properties. This thesis reports on the synthesis and characterization of the nanocrystalline TiO2 ceramic in details. The study selected a simple sol-gel synthesis process, which can be easily controlled and reproduced. Titanium tetraisopropoxide, isopropanol and deionized water were used as starting materials. By careful control of relative proportion …
Analytic Webs Support The Synthesis Of Ecological Data Sets, Aaron M. Ellison, Leon J. Osterweil, Lori Clarke, Julian L. Hadley, Alexander Wise, Emery Boose, David R. Foster, Allen Hanson, David Jensen, Paul Kuzeja, Edward Riseman, Hward Schultz
Analytic Webs Support The Synthesis Of Ecological Data Sets, Aaron M. Ellison, Leon J. Osterweil, Lori Clarke, Julian L. Hadley, Alexander Wise, Emery Boose, David R. Foster, Allen Hanson, David Jensen, Paul Kuzeja, Edward Riseman, Hward Schultz
Computer Science Department Faculty Publication Series
A wide variety of data sets produced by individual investigators are now synthesized to address ecological questions that span a range of spatial and temporal scales. It is important to facilitate such syntheses so that ‘‘consumers’’ of data sets can be confident that both input data sets and synthetic products are reliable. Necessary documentation to ensure the reliability and validation of data sets includes both familiar descriptive metadata and formal documentation of the scientific processes used (i.e., process metadata) to produce usable data sets from collections of raw data. Such documentation is complex and difficult to construct, so it is …
Effect Of Nitric Oxide On Oxygen Consumption Of Skeletal Muscle, Christina Lyn Cox
Effect Of Nitric Oxide On Oxygen Consumption Of Skeletal Muscle, Christina Lyn Cox
Theses and Dissertations
Mammalian cells require a continuous and sufficient supply of oxygen to carry out their functions. The oxygen pathway has an overall direction taking O2 from the air to the mitochondria, which is a result of the mitochondrial O2 consumption (VO2) NO various effects on the mitochondria: at low concentrations for short periods NO specifically and irreversibly inhibits cytochrome c and reversibly inhibits cytochrome c oxidase, to decrease VO2. Thus, NO can modulate VO2 of skeletal muscle. The purpose of the present study was to measure VO2 of the rat spinotrapezius muscle under conditions of altered NO. The methods used provide …
Synthesis And Characterization Of Metal Complexes Of Cu(Ii), Ni(Ii), Zn(Ii), Co(Ii), Mn(Ii) And Cd(Ii) With Tetradentate Schiff Bases, Jianning Liu, Bo-Wan Wu, Bing Zhang, Yongchun Liu
Synthesis And Characterization Of Metal Complexes Of Cu(Ii), Ni(Ii), Zn(Ii), Co(Ii), Mn(Ii) And Cd(Ii) With Tetradentate Schiff Bases, Jianning Liu, Bo-Wan Wu, Bing Zhang, Yongchun Liu
Turkish Journal of Chemistry
4-(Benzeneazo)salicylaldehyde was synthesized with aniline, sodium nitrite and salicylaldehyde. Two tetradentate ligands, N,N'-bis[4-(benzeneazo) salicylaldehyde]-o-phenylenediamine (H_2L) and N,N'-bis[4-(benzeneazo) salicylaldehyde]ethylenediamine (H_2L') were formed by the 2:1 molar condensation of 4-(benzeneazo) salicylaldehyde with o-phenylenediamine or ethylenediamine. Their Cu(II), Ni(II), Zn(II), Co(II), Mn(II) and Cd(II) complexes were synthesized and characterized by elemental analysis, molar conductivity measurements, and infrared and electronic spectral data. Two ligands and their Ni(II) and Zn(II) complexes were further identified using ^1H NMR spectra. The results suggest that the metal is bonded to the ligand through the phenolic oxygen and the imino nitrogen.
Synthesis Of New 3-Pyrrolin-2-One Derivatives, Nezi̇re Saygili, Ayşegül Altunbaş, Akgül Yeşi̇lada
Synthesis Of New 3-Pyrrolin-2-One Derivatives, Nezi̇re Saygili, Ayşegül Altunbaş, Akgül Yeşi̇lada
Turkish Journal of Chemistry
Six new 3-pyrrolin-2-one derivatives were synthesized via the condensation reaction of amino acid esters (2a-f) with 2,5-dimethoxy-2,5-dihydrofurane (1) in acidic medium. This simple one-pot reaction furnished the corresponding pyrrolinones (3a-f) in acceptable yields.
Synthesis, Characterization, Crystal Structure And Thermal Behavior Of N'-(4-Chlorobenzoyl)-N,N-Di-N-Butylthiourea And Its Nickel Complex, Hakan Arslan, Ulrich Flörke, Nevzat Külcü, Esra Kayhan
Synthesis, Characterization, Crystal Structure And Thermal Behavior Of N'-(4-Chlorobenzoyl)-N,N-Di-N-Butylthiourea And Its Nickel Complex, Hakan Arslan, Ulrich Flörke, Nevzat Külcü, Esra Kayhan
Turkish Journal of Chemistry
We report the synthesis, structural characterization and thermal behavior of N'-(4-chlorobenzoyl)-N,N-di-n-butylthiourea (HL) and its nickel complex (NiL_2). Some physical properties of the prepared compounds were investigated using elemental analyses, IR, ^1H-NMR, and magnetic susceptibility. The molecular structures of HL and NiL_2 were determined by single crystal X-ray diffraction. HL is a monoclinic, space group P2_1/c with a = 10.7457(5) Å, b = 15.5909(8) Å, c = 10.4536(5) Å, \beta = 104.398(1)°, and V = 1696.34(14) Å^3 with Z = 4 for d_{calc} = 1.280 g/cm^3. NiL_2 is a triclinic, space group P-1 with a = 8.561(3) Å, b = 16.643(6) …
The Mechanism And Crystal Structure Of 2-Methoxy-2-Methyl-4-Phenyl-3,4,4a, 10b-Tetrahydro-2h,5h-Pyrano[3,2-C]Chromen-5-One. Acetal Of Warfarin Acid, Saira Shahzadi, Saqib Ali, Irum Asif, Rizwana Ashraf, Guo-Xin Jin
The Mechanism And Crystal Structure Of 2-Methoxy-2-Methyl-4-Phenyl-3,4,4a, 10b-Tetrahydro-2h,5h-Pyrano[3,2-C]Chromen-5-One. Acetal Of Warfarin Acid, Saira Shahzadi, Saqib Ali, Irum Asif, Rizwana Ashraf, Guo-Xin Jin
Turkish Journal of Chemistry
Acetal of warfarin acid has been synthesized via a hemi acetal intermediate and structurally characterized by X-ray diffraction. The crystal structure shows that the title compound was formed by the hydrolysis of warfarin acid in methanol at pH 3, with space group P2_1/n and unit cell parameters a = 5.859 (17), b =16.745 (5), c = 16.402 (5) Å, \alpha = 90.00; \beta = 94.853 (4), and \gamma = 90.00°.
Template Synthesis And Structural Characterization Of Homo Binuclear Chromium(Iii), Manganese(Iii), Iron(Iii), Cobalt(Iii), And Ruthenium(Iii) Complexes With Octaazamacrocyclic Ligands, Vinod K. Sharma, Shipra Srivastava
Template Synthesis And Structural Characterization Of Homo Binuclear Chromium(Iii), Manganese(Iii), Iron(Iii), Cobalt(Iii), And Ruthenium(Iii) Complexes With Octaazamacrocyclic Ligands, Vinod K. Sharma, Shipra Srivastava
Turkish Journal of Chemistry
The Schiff base octaazamacrocyclic ligands derived from primary diamines and 3,6-dimethyl/diphenyl-4,5-diazaocta-3,5-diene-2,7-dione, and their binuclear complexes [M_2LCl_4]Cl_2 [M = Cr(III), Fe(III), Co(III), or Ru(III)] and [Mn_2L(AcO)_4](AcO)_2 were synthesized by template condensation reactions. Attempts to synthesize the corresponding metal-free macrocyclic ligands did not prove successful. The overall geometry and stereochemistry of these complexes were elucidated by elemental analyses, magnetic susceptibilities, electronic spectra, infrared spectra, molar conductance measurements, ^1H NMR, and thermogravimetric analysis. All the trivalent metal ion complexes appear to be 1:2 electrolytes. An octahedral geometry is proposed for all the complexes.
Synthesis And Anticancer Evaluation Of Some New Unsymmetrical 3,5-Diaryl-4h-1,2,4-Triazole Derivatives, Olcay Beki̇rcan, Bahi̇tti̇n Kahveci̇, Murat Küçük
Synthesis And Anticancer Evaluation Of Some New Unsymmetrical 3,5-Diaryl-4h-1,2,4-Triazole Derivatives, Olcay Beki̇rcan, Bahi̇tti̇n Kahveci̇, Murat Küçük
Turkish Journal of Chemistry
A series of 4-arylidenamino-4H-1,2,4-triazole derivatives (3-11) were synthesized from the treatment of 4-amino-4H-1,2,4-triazoles (2) with certain aldehydes. Compounds 3-11 were reduced with NaBH_4 to afford the corresponding 4-arylmethylenamino-4H-1,2,4-triazoles (12-20). Compounds 1-10 and 12-19 were characterized by elemental analyses and ^1H NMR, ^{13}C NMR, IR and UV spectral data. Compounds 11 and 20 were characterized by ^1H NMR, ^{13}C NMR, IR and mass spectral data. Compounds 14, 16, 17, and 18 were tested for anticancer activities. Compound 17, chosen for its higher anticancer activity in the preliminary tests with the cancer cell lines of MCF7, NCI-H460, and SF-268, exhibited remarkable anticancer …
Low Oxidation State Group 15 Cations: Synthesis, Reactivity And Computational Studies, Bobby Dean Ellis
Low Oxidation State Group 15 Cations: Synthesis, Reactivity And Computational Studies, Bobby Dean Ellis
Electronic Theses and Dissertations
No abstract provided.
The Lived Experience Of Nurses Working With Student Nurses In The Acute Care Clinical Environment, Donna Coffey Hathorn
The Lived Experience Of Nurses Working With Student Nurses In The Acute Care Clinical Environment, Donna Coffey Hathorn
LSU Doctoral Dissertations
The purpose of this phenomenological qualitative study was to describe the lived experience of nurses’ who work with baccalaureate student nurses in the acute care clinical environment. Because of the nursing shortage nursing education is challenged with equipping a safe qualified workforce while preventing or reducing student attrition. Students may choose to leave the profession or receive less than optimal learning experiences when exposed to negative socialization behaviors of nurses while in the clinical environment. Findings from this study can be used to foster collaboration between nursing education and nursing service in the development of positive clinical environments for nurses …