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Thomas Jefferson University

2016

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Scitech News Volume 70, No. 4 (2016) Dec 2016

Scitech News Volume 70, No. 4 (2016)

Sci-Tech News

Columns and Reports

From the Editor 3

Division News

Science-Technology Division 4

SLA Annual Meeting 2016 Report (S. Kirk Cabeen Travel Stipend Award recipient) 6

Reflections on SLA Annual Meeting (Diane K. Foster International Student Travel Award recipient) 8

SLA Annual Meeting Report (Bonnie Hilditch International Librarian Award recipient)10

Chemistry Division 12

Engineering Division 15

Reflections from the 2016 SLA Conference (SPIE Digital Library Student Travel Stipend recipient)15

Fundamentals of Knowledge Management and Knowledge Services (IEEE Continuing Education Stipend recipient) 17

Makerspaces in Libraries: The Big Table, the Art Studio or Something Else? (by Jeremy Cusker) 19

Aerospace Section of …


News In Brief Nov 2016

News In Brief

Jefferson Surgical Solutions

Matthew P. Jenkins, MD, has joined the Division of Plastic Surgery. Dr. Jenkins completed his general surgery residency at Temple University Hospital in 2013 and remained there for fellowship training in Plastic and Reconstructive Surgery. He is board certified and sees patients at Thomas Jefferson University Hospital.

Anirudh Kohli, MD, has joined the Division of Acute Care Surgery. Dr. Kohli completed his general surgery residency at the Montefiore Medical Center at the Albert Einstein College of Medicine in New York, followed by a fellowship in Surgical Critical Care at Cooper University Hospital in Camden, NJ. He is board …


For Cygan Clan, Raising Funds Honors Sister And Strengthens Family Ties Nov 2016

For Cygan Clan, Raising Funds Honors Sister And Strengthens Family Ties

Jefferson Surgical Solutions

On May 21, 2016, 250 participants and 70 volunteers came together for the second Amy’s Ride/Run/Walk, which raises money for pancreatic cancer research in honor of Amy Cygan Spier. One of 11 siblings, Amy was just 54 years old when she succumbed to pancreatic cancer in November 2014. For the brothers and sisters she left behind, the event is a labor of love.

The idea for a fundraiser began to take shape after the Cygans learned how comparatively little money is devoted to pancreatic cancer research. With a number of cyclists in the family, a bike ride seemed like a …


On The Job: Velvet Cain Nov 2016

On The Job: Velvet Cain

Jefferson Surgical Solutions

While the Department of Surgery is renowned for operating on people, Velvet Cain specializes in another type of “surgery”: analyzing and managing complex numbers. As the Department’s Senior Financial Analyst, she is instrumental in planning budgets, tracking expenses, generating reports and monitoring various components of compensation for faculty and nonfaculty staff.

Velvet joined Jefferson in 1999 as a staff accountant in the Controller’s Office. She transferred to Jefferson University Physicians’ Finance Department in 2001 before assuming her current position in Surgery in 2007. While she has remained in the same role, her dayto- day work has changed dramatically over the …


Alliric Willis Leads Study Exploring Demographics, Disparities And Outcomes In Substernal Goiters Nov 2016

Alliric Willis Leads Study Exploring Demographics, Disparities And Outcomes In Substernal Goiters

Jefferson Surgical Solutions

Lack of iodine makes goiters— enlargement of the thyroid gland in the neck—common in some parts of the world. In the United States, salt is enriched with iodine, so the condition is far less common. When goiters do occur, it is typically due to other factors, such as Graves’ disease (overactive thyroid) or Hashimoto’s disease (underactive thyroid), as well as an individual’s anatomy or family history. And when goiters go untreated, they can grow down into the chest, spreading behind the breastbone and collarbone; in some cases, they grow all the way down to the arch of the aorta. These …


Meet The Interns Nov 2016

Meet The Interns

Jefferson Surgical Solutions

The Department has welcomed a dynamic group of categorical interns including one graduate of Sidney Kimmel Medical College at Thomas Jefferson University. The interns were selected from over 1200 applicants to our program. These doctors, who recently matched with Jefferson, started on June 20, 2016. Please welcome:

Peter Altshuler, MD Sidney Kimmel Medical College

Kashmira Chawla, MD Mayo Medical School

Thomas O’Malley, MD Tulane University School of Medicine

Arturo Rios Diaz, MD Universidad Central de Venezuela

Steven Woodward, MD University of Maryland School of Medicine

Alicja Zalewski, MD Rutgers University – New Jersey Medical School

We are also pleased to …


Smoking Cessation, Counseling & Therapy Program Helps Patients Kick The Habit Nov 2016

Smoking Cessation, Counseling & Therapy Program Helps Patients Kick The Habit

Jefferson Surgical Solutions

The Department of Surgery’s Smoking Cessation, Counseling & Therapy (SCCT) Program offers evidencebased strategies for quitting smoking, including one-on-one counseling, nicotine replacement therapy and prescription medication, such as Chantix and Wellbutrin, to reduce cravings and lessen withdrawal symptoms. Although the program started as a resource for patients preparing for cardiac or thoracic surgery, it is now available to many more patients—and nurse practitioners Chuck Rowland, MSN, CRNP, CTTS, and Sung Whang, MSN, CRNP, CTTS, are eager to spread the word.

Chuck and Sung are both Certified Tobacco Treatment Specialists (CTTS). They each completed an intensive 40-hour course offered by the …


Departmental Retreat: The Big Four And Integration, Charles J. Yeo, Md, Facs Nov 2016

Departmental Retreat: The Big Four And Integration, Charles J. Yeo, Md, Facs

Jefferson Surgical Solutions

Fall is here, excitement is in the air, and we in the Department of Surgery have begun the journey towards clinical integration with our partners at Abington and Aria.

On Saturday, September 24, 2016, nearly 100 attendees joined us in the Hamilton Building for our second Department of Surgery retreat in the last 18 months. This retreat differed from our first as we focused on two topics: The Big Four and Jefferson Health System Integration.

The morning commenced with a reminder of our vision and mission statements, a review of the fiscal exigencies which prompted a need for change, and …


Surgeon Speaks Nov 2016

Surgeon Speaks

Jefferson Surgical Solutions

Patients who undergo liver transplantation go from being very sick to reclaiming their lives. It’s a rapid and rewarding transformation. The notion that there are still places in the world where this surgery isn’t available is a problem. No one should die of liver disease because of lack of funding.

The city of Santa Cruz has surgeons who operate every day. They want to learn how to do liver transplants, but there wasn’t anyone to teach them. It’s an honor to work to help change that.

While our work in Bolivia may not be solving the problem globally, it is …


Stephen Dunn And Warren Maley Volunteer Transplantation Services, Expertise In Bolivia Nov 2016

Stephen Dunn And Warren Maley Volunteer Transplantation Services, Expertise In Bolivia

Jefferson Surgical Solutions

More than 20 years ago, Stephen P. Dunn, MD, FACS, Professor of Pediatric Surgery at Jefferson, encountered a young liver transplant patient who had traveled from his home in Santa Cruz, Bolivia, to St. Christopher’s Hospital for Children. After inquiring why the boy hadn’t been transplanted in his home country, Dr. Dunn learned that while surgeons in Santa Cruz had a fair amount of experience with kidney transplants, they were not able to perform liver transplants. In order to have these life-saving surgeries, patients in Santa Cruz needed the funds not only to pay for the operation but also to …


Jcph Publications And Presentations Nov 2016

Jcph Publications And Presentations

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Caroline Golab's Retirement Party Nov 2016

Caroline Golab's Retirement Party

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


In The News Nov 2016

In The News

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Improving Health Outcomes In Under-Served Communities Nov 2016

Improving Health Outcomes In Under-Served Communities

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


The Prominent Role Of The Nurse In Healthcare Legislation And Advocacy, Carol Ann Gioia Rn, Msn, Nea-Bc Nov 2016

The Prominent Role Of The Nurse In Healthcare Legislation And Advocacy, Carol Ann Gioia Rn, Msn, Nea-Bc

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Creating A Culture Of Employee Health At Jefferson Through Partnership With Healthnext, Allison Wozniak Nov 2016

Creating A Culture Of Employee Health At Jefferson Through Partnership With Healthnext, Allison Wozniak

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Creativity, Technology And Public Health: Mph Students Reflect On Nexus Maximus 2016 At Philadelphia University, J. Wes Heinle, Steve Orellana, Cordelia Elaiho, Roxanne Erolin, Karla Geiss Nov 2016

Creativity, Technology And Public Health: Mph Students Reflect On Nexus Maximus 2016 At Philadelphia University, J. Wes Heinle, Steve Orellana, Cordelia Elaiho, Roxanne Erolin, Karla Geiss

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Rolling The Dice On The Social Determinants Of Health, Amy Leader Nov 2016

Rolling The Dice On The Social Determinants Of Health, Amy Leader

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Bridging The Gaps: A Wealth Of Learning On The Front Line, Kerona Sharpe, Sydney Shuster Nov 2016

Bridging The Gaps: A Wealth Of Learning On The Front Line, Kerona Sharpe, Sydney Shuster

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


My Road To Jefferson And The Path Ahead, Willie H. Oglesby Phd, Msph, Fache Nov 2016

My Road To Jefferson And The Path Ahead, Willie H. Oglesby Phd, Msph, Fache

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Population Health Matters Fall 2016, Download Issue Nov 2016

Population Health Matters Fall 2016, Download Issue

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Download Entire Bodine Journal Volume 1, Issue 1, 2008 Nov 2016

Download Entire Bodine Journal Volume 1, Issue 1, 2008

Bodine Journal

No abstract provided.


Factors Associated With Severe Late Toxicity After Concurrent Chemoradiation For Locally Advanced Head And Neck Cancer: An Rtog Analysis, Mitchell Machtay, Md, Jennifer Moughan, Ms, Andrew Trotti, Md, Adam S. Garden, Md, Randal S. Weber, Md, Jay S. Cooper, Md, Arlene Forastiere, Md, K. Kian Ang, Md Nov 2016

Factors Associated With Severe Late Toxicity After Concurrent Chemoradiation For Locally Advanced Head And Neck Cancer: An Rtog Analysis, Mitchell Machtay, Md, Jennifer Moughan, Ms, Andrew Trotti, Md, Adam S. Garden, Md, Randal S. Weber, Md, Jay S. Cooper, Md, Arlene Forastiere, Md, K. Kian Ang, Md

Bodine Journal

Purpose

Concurrent chemoradiotherapy (CCRT) for squamous cell carcinoma of the head and neck (SCCHN) increases both local tumor control and toxicity. This study evaluates clinical factors that are associated with and might predict severe late toxicity after CCRT.

Methods

Patients were analyzed from a subset of three previously reported RTOG trials of concurrent chemoradiotherapy for locally advanced SCCHN (RTOG 91-11; 97-03; and 99-14). Severe late toxicity was defined in this secondary analysis as chronic Grade 3-4 pharyngeal/laryngeal toxicity (RTOG/EORTC late toxicity scoring system) and/or requirement for a feeding tube ≥2 years after registration and/or potential treatment-related death (e.g. pneumonia) within …


Increasing Tumor Volume Is Predictive Of Poor Overall And Progression-Free Survival: Secondary Analysis Of The Radiation Therapy Oncology Group 93-11 Phase I-Ii Radiation Dose-Escalation Study In Patients With Inoperable Non-Small-Cell Lung Cancer, Maria Werner-Wasik, R. Suzanne Swann, Phd, Jeffrey Bradley, Md, Mary Graham, Md, Bahman Emani, Md, James Purdy, Phd, William Sause, Md Nov 2016

Increasing Tumor Volume Is Predictive Of Poor Overall And Progression-Free Survival: Secondary Analysis Of The Radiation Therapy Oncology Group 93-11 Phase I-Ii Radiation Dose-Escalation Study In Patients With Inoperable Non-Small-Cell Lung Cancer, Maria Werner-Wasik, R. Suzanne Swann, Phd, Jeffrey Bradley, Md, Mary Graham, Md, Bahman Emani, Md, James Purdy, Phd, William Sause, Md

Bodine Journal

Purpose

Patients with non–small-cell lung cancer (NSCLC) in the Radiation Therapy Oncology Group (RTOG) 93-11 trial received radiation doses of 70.9, 77.4, 83.8, or 90.3 Gy. The locoregional control and survival rates were similar among the various dose levels.We investigated the effect of the gross tumor volume (GTV) on the outcome.

Methods and Materials

The GTV was defined as the sum of the volumes of the primary tumor and involved lymph nodes. The tumor response, median survival time (MST), and progression-free survival (PFS) were analyzed separately for smaller (≤45 cm3) vs. larger (>45 cm3) tumors.

Results

The distribution of …


Inhibition Of P73 Function By Pifithrin-Α As Revealed By Studies In Zebrafish Embryos, William R Davidson, Qing Ren, Gabor Kari, Ori Kashi, Adam Dicker Md, Phd, Ulrich Rodeck Nov 2016

Inhibition Of P73 Function By Pifithrin-Α As Revealed By Studies In Zebrafish Embryos, William R Davidson, Qing Ren, Gabor Kari, Ori Kashi, Adam Dicker Md, Phd, Ulrich Rodeck

Bodine Journal

The p53 family of proteins contains two members that have been implicated in sensitization of cells and organisms to genotoxic stress, i.e., p53 itself and p73. In vitro, lack of either p53 or p73 can protect certain cell types in the adult organism against death upon exposure to DNA damaging agents. The present study was designed to assess the relative contribution of p53 to radiation resistance of an emerging vertebrate model organism, i.e., zebrafish embryos. Consistent with previous reports, suppressing p53 protein expression using antisense morpholino oligonucleotides (MOs) increased survival and reduced gross morphological alterations in zebrafish embryos exposed to …


Vegf Trap In Combination With Radiotherapy Improves Tumor Control In U87 Glioblastoma, Phyllis Wachsberger, Phd, Randy Burd, Phd, Chris Cardi, Ms, Mathew L. Thakur, Constantine Daskalakis, Jocelyn Holash, Phd, George D. Yancopoulos, Phd, Adam Dicker Md, Phd Nov 2016

Vegf Trap In Combination With Radiotherapy Improves Tumor Control In U87 Glioblastoma, Phyllis Wachsberger, Phd, Randy Burd, Phd, Chris Cardi, Ms, Mathew L. Thakur, Constantine Daskalakis, Jocelyn Holash, Phd, George D. Yancopoulos, Phd, Adam Dicker Md, Phd

Bodine Journal

Purpose

To determine the effect of vascular endothelial growth factor VEGF Trap (Regeneron Pharmaceuticals, Tarrytown, NY), a humanized soluble vascular endothelial growth factor (VEGF) receptor protein, and radiation (RT) on tumor growth in U87 glioblastoma xenografts in nude mice.

Methods and Materials

U87 cell suspensions were implanted subcutaneously into hind limbs of nude mice. VEGF Trap (2.5–25 mg/kg) was administered every 3 days for 3 weeks alone or in combination with a single dose of 10 Gy or fractionated RT (3 x 5 Gy). In addition, three scheduling protocols for VEGF Trap plus fractionated RT were examined.

Results

Improved tumor …


A Cone Beam Ct-Based Study For Clinical Target Definition Using Pelvic Anatomy During Post-Prostatectomy Radiotherapy, Timothy Showalter Md, A. Omer Nawaz, Ma, Ying Xiao, James Galvin Phd, Richard K. Valicenti, Md Nov 2016

A Cone Beam Ct-Based Study For Clinical Target Definition Using Pelvic Anatomy During Post-Prostatectomy Radiotherapy, Timothy Showalter Md, A. Omer Nawaz, Ma, Ying Xiao, James Galvin Phd, Richard K. Valicenti, Md

Bodine Journal

Introduction:

Radiation therapy (RT) is delivered after radical prostatectomy (RP) either as salvage treatment for an elevated prostate-specific antigen (PSA) level1-6 or as adjuvant therapy for patients with highrisk pathologic features7-8. Recent prospective data demonstrated a disease-free survival benefit of adjuvant RT for pathologic T3N0 prostate cancer9-10. Despite literature supporting the delivery of post-RP RT to the prostatic fossa (PF), no clear target definition guidelines exist for intensity modulated radiation therapy (IMRT) or image-guided RT (IGRT)11.

Visualization of the PF is limited on standard CT images, with significant interobserver variability and uncertainty in CTV definition12. Efforts to incorporate complementary imaging …


Toxicity Of Radiotherapy In Patients With Collagen Vascular Disease, Alexander Lin, Md, Eyad Abu-Isa, Md, Kent A. Griffith, Mph, Ms, Edgar Ben-Josef, Md Nov 2016

Toxicity Of Radiotherapy In Patients With Collagen Vascular Disease, Alexander Lin, Md, Eyad Abu-Isa, Md, Kent A. Griffith, Mph, Ms, Edgar Ben-Josef, Md

Bodine Journal

Background

A diagnosis of collagen vascular disease (CVD) may predispose to radiotherapy (RT) toxicity. The objective of the current study was to identify factors that influence RT toxicity in the setting of CVD.

Methods

A total of 86 RT courses for 73 patients with CVD were delivered between 1985 and 2005. CVD subtypes include rheumatoid arthritis (RA; 33 patients), systemic lupus erythematosus (SLE; 13 patients), scleroderma (9 patients), dermatomyositis/polymyositis (5 patients), ankylosing spondylitis (4 patients), polymyalgia rheumatica/temporal arteritis (4 patients), Wegener granulomatosis (3 patients), and mixed connective tissue disorders (MCTD)/other (2 patients). Each patient with CVD was matched to 1 …


Table Of Contents: Bodine Journal Volume 1, Issue 1, Fall 2008 Nov 2016

Table Of Contents: Bodine Journal Volume 1, Issue 1, Fall 2008

Bodine Journal

No abstract provided.


Download Entire Bodine Journal Volume 2, Issue 1, 2009 Nov 2016

Download Entire Bodine Journal Volume 2, Issue 1, 2009

Bodine Journal

No abstract provided.