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Neuronal And Molecular Adaptations Of Gaba Neurons In The Ventral Tegmental Area To Chronic Alcohol, Kimberly Hales
Neuronal And Molecular Adaptations Of Gaba Neurons In The Ventral Tegmental Area To Chronic Alcohol, Kimberly Hales
Theses and Dissertations
The purpose of this thesis project was to examine the effects of chronic alcohol on the excitability and molecular adaptation of GABA neurons of the ventral tegmental area (VTA). GABA neurons are of interest with regards to ethanol intoxication, reinforcement, and dependence due to their widespread distribution and connectivity to mesocorticolimbic dopamine (DA) neurons implicated in alcohol reward and addiction. Since we have previously shown adaptation of VTA GABA neuron firing rate to chronic ethanol (Gallegos, Criado et al. 1999) and suppression of gap-junction (GJ) mediated coupling between these neurons by acute ethanol (Stobbs, Ohran et al. 2004), we wanted …
Religiosity, Parental Support And Adult Support Coping As Protective Factors For Drug Refusal Efficacy And Use Among African American Adolescents, Raymond H. Tademy
Religiosity, Parental Support And Adult Support Coping As Protective Factors For Drug Refusal Efficacy And Use Among African American Adolescents, Raymond H. Tademy
Theses and Dissertations
This study examined whether religiosity, parental and adult support coping would moderate the influence of neighborhood risks and friends' drug use upon drug refusal efficacy and drug use among African American adolescents. One hundred and thirteen African American urban adolescents (77 females and 36 males) aged 11-17 (M=14.17) participated in this study. This study used the God Support and Religious Support scales to assess religiosity; the parental support coping subscale of the Wills Coping measure; Center for Substance Abuse Prevention's Special Event Drug Refusal Efficacy and Friends' Drug use scales; the Exposure to Neighborhood Risk Scale; and a one-item measure …