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High Flow Nasal Cannula And Non-Invasive Mechanical Ventilation In Management Of Covid-19 Associated Respiratory Failure, Hanady Mohammad Elfeky, Ayman Ahmed Rady, Ashraf Mohamed Mostafa, Menan Hany Nassar, Amany Ali Sultan Jan 2024

High Flow Nasal Cannula And Non-Invasive Mechanical Ventilation In Management Of Covid-19 Associated Respiratory Failure, Hanady Mohammad Elfeky, Ayman Ahmed Rady, Ashraf Mohamed Mostafa, Menan Hany Nassar, Amany Ali Sultan

Menoufia Medical Journal

Objectives: To analyze the clinical data and outcomes of different non-invasive oxygen therapy modalities used for the treatment of type 1 respiratory failure associated with COVID 19 virus infection. Background: Despite the variety of oxygen delivery modes, there is still uncertainty regarding the benefit of HFNC as a non-invasive oxygen delivery method during the coronavirus pandemic. Methods: In 100 patients with ARF associated with COVID-19, We performed an observational prospective cohort study in which they divided into the NIV and HFNC groups. The primary outcome was treatment failure, characterized by switching to invasive mechanical ventilation or the other oxygen therapy …


Study Of Tp53 Gene Expression In Multiple Sclerosis Patients, Enas Said Essa, Safa Sayed Meshaal, Ahmed Nabil Mounir, Zahraa Azab Mohamed Abouelatta Jan 2024

Study Of Tp53 Gene Expression In Multiple Sclerosis Patients, Enas Said Essa, Safa Sayed Meshaal, Ahmed Nabil Mounir, Zahraa Azab Mohamed Abouelatta

Menoufia Medical Journal

Objectives: to evaluate the role of TP53 gene expression as a potential biomarker for multiple sclerosis. Background: Multiple sclerosis (MS) is the most prevalent non-traumatic illness among young adults. The frequency of MS and its socioeconomic effects are growing globally. Up until now, the diagnosis of MS has been considered a big challenge as it depends on a group of findings known as the McDonald criteria. However, none of those criteria is particularly specific to MS disease. This study aims to evaluate TP53 gene expression as a diagnostic marker for MS. Methods: Twenty-eight MS cases were recruited according to modified …


Relationship Between Non-Alcoholic Steatohepatitis And Left Ventricular Diastolic Dysfunction In Type 2 Diabetic Patients, Alaa Eldin A. Dawood, Mervat A. Mostafa, Wessam E. El-Shafey, Esraa N. Abo El-Rous, Shimaa K. Zewain Jan 2024

Relationship Between Non-Alcoholic Steatohepatitis And Left Ventricular Diastolic Dysfunction In Type 2 Diabetic Patients, Alaa Eldin A. Dawood, Mervat A. Mostafa, Wessam E. El-Shafey, Esraa N. Abo El-Rous, Shimaa K. Zewain

Menoufia Medical Journal

Objectives: To determine if the poor diastolic function of the left ventricle was independently correlated with hepatic steatosis and fibrosis in type 2 diabetes mellitus (T2DM). Background: There is growing evidence that it is related to nonalcoholic fatty liver disease (NAFLD) and left ventricular diastolic dysfunction (LVDD). We sought to learn more about the relationship between LV diastolic dysfunction and liver fibrosis in T2DM patients. Methods: a case control study was conducted on 100 patients, 50 of them with type 2 diabetes patients without NAFLD and 50 diabetic patients with NAFLD. NAFLD fibrosis score (NFS) and abdominal ultrasonography were used …


Modified Inferior Based Reduction Mammoplasty Versus Matrix Rotational Flap In Upper Inner Quadrant Breast Cancer, Abdelaziz Ragab Abdelaziz Sakr, Alaa Abd Elazeem Elsisi, Tarek Mohey Rageh, Mahmoud Ahmed Shahin Jan 2024

Modified Inferior Based Reduction Mammoplasty Versus Matrix Rotational Flap In Upper Inner Quadrant Breast Cancer, Abdelaziz Ragab Abdelaziz Sakr, Alaa Abd Elazeem Elsisi, Tarek Mohey Rageh, Mahmoud Ahmed Shahin

Menoufia Medical Journal

Objectives: to compare between inferior pedicle mammaplasty and matrix rotational advancement flap as techniques for upper inner quadrant breast cancers regarding oncoplastic and aesthetic results. Background: Breast conserving therapy (BCT) is the standard of care in early breast cancer; has a value to provide a treatment as effective as mastectomy with benefits of breast preservation. However, traditional conservative surgery in the upper inner quadrant may not have good cosmetic results. Methods: All 30 patients were candidates for breast conservation and with upper inner breast tumors; patients were randomly categorized into two groups. Group A (16 patients) included patients who underwent …


Enhanced Recovery For Patients Undergoing Radical Cystectomy. A Randomized Controlled Study, Ashraf M Eskandr, Ezzeldin S Ibrahim, Mohamed M Abdallah, Asmaa I Elzwedy, A.M. Sedky Jan 2024

Enhanced Recovery For Patients Undergoing Radical Cystectomy. A Randomized Controlled Study, Ashraf M Eskandr, Ezzeldin S Ibrahim, Mohamed M Abdallah, Asmaa I Elzwedy, A.M. Sedky

Menoufia Medical Journal

Objective: To evaluate the effectiveness of the enhanced recovery protocol versus traditional care on postoperative hospital stay, patients, recovery and complications in patients undergoing radical cystectomy. Background: Despite improvements in surgical technique, anesthesia, and perioperative care, radical cystectomy is still associated with significant morbidity and prolonged hospital stay after surgery more than other urological procedures. Methods: This study included 50 adult patients of both sexes, ASA (American Society of anesthesiology) II-III physical status, aged 40-70 years, scheduled for radical cystectomy. Patients were randomly divided into two equal groups: 25 patients following enhanced recovery protocol after surgery (ERAS group) and 25 …


Percutaneous Vertebroplasty: A Minimally Invasive Procedure For The Management Of Dorsolumbar Compression Fractures, Yasser Bahgat Elsisi, Ahmed Gabry El Nagar, Osama Saber Shereef Jan 2024

Percutaneous Vertebroplasty: A Minimally Invasive Procedure For The Management Of Dorsolumbar Compression Fractures, Yasser Bahgat Elsisi, Ahmed Gabry El Nagar, Osama Saber Shereef

Menoufia Medical Journal

Objectives: to study percutaneous vertebroplasty in the management of compression fractures of thoracolumbar spine regarding its advantages, drawbacks, complications, and outcome. Background: The lifetime risk of a vertebral body compression fracture is 16% for women and 5% for men. Vertebroplasty require the clinician to be experienced in spinal anatomy, fluoroscopic imaging, and the use of these methods to perform interventional procedures. Methods: a retrospective study over a 3-year period, cluster sample of patients. 30 patients with stable compression fractures from January 2018 to January 2021 who were surgically treated by percutaneous vertebroplasty at the Neurosurgery Department, Faculty of Medicine, Menoufia …


Evaluation Of Myocardial Function In Neonatal Sepsis Using Tissue Doppler Imaging, Fahima Mohamed Hassan, Dina Abdel Razek Midan, Afaf Hassan Sayed Ahmed El Roba, Basim Abdelfattah Ali Elgazzar Jan 2024

Evaluation Of Myocardial Function In Neonatal Sepsis Using Tissue Doppler Imaging, Fahima Mohamed Hassan, Dina Abdel Razek Midan, Afaf Hassan Sayed Ahmed El Roba, Basim Abdelfattah Ali Elgazzar

Menoufia Medical Journal

Objectives: To assess the ventricular function in neonatal sepsis using tissue Doppler imaging (TDI). Background: A leading cause of newborn morbidity and mortality is neonatal sepsis. Cardiac dysfunction is a significant side effect of severe sepsis. Methods: This study is a prospective case-control study that was conducted from August 2020 to March 2021with 50 neonates having culture-proven sepsis (cases), recruited from Neonatal Intensive Care Unit (NICU) of Menoufia University Hospital together with another 50 age and sex-matched sepsis-free neonates (control). Patients were subjected to history taking, clinical examination, routine investigations (complete blood count (CBC), quantitative C-reactive protein, ALT, AST, creatinine, …


Serum Neuron-Specific Enolase And S100Β Protein As Serum Biomarkers Of Brain Injury To Classify Outcome After Pediatric Sepsis, Fady M Elgendy, Fahima M Hasaan, Hassan S Bader, Mohamed S Rizk, Neveen M Fawzy Jan 2024

Serum Neuron-Specific Enolase And S100Β Protein As Serum Biomarkers Of Brain Injury To Classify Outcome After Pediatric Sepsis, Fady M Elgendy, Fahima M Hasaan, Hassan S Bader, Mohamed S Rizk, Neveen M Fawzy

Menoufia Medical Journal

Objectives: To evaluate serum neuron-specific enolase and S100β protein as biomarkers for the detection of brain injury in pediatric sepsis and mortality. Background Septic-associated encephalopathy (SAE) is a common manifestation of sepsis, which associated with higher rates of mortality.

Methods: This case-control study was conducted on 45 septic cases admitted to the Pediatric Intensive Care Unit (PICU), Pediatric Department, Menoufia University Hospitals and 45 apparently healthy children. NSE and S100β protein serum biomarkers were measured by ELISA kits in the second day of sepsis diagnosis and patients were followed for a month.

Results: There was a highly significant increase in …


Lupus Kidney Disease Spectrum And Characteristics Among Egyptian Adults And Children With Sle, Emad Mohammad Elshebiny, Simon Alphonse Botros, Mohamed Shokry Elharoun, Zeinab Abdelaziz Kasemy, Samar Tharwat Radwan, Enas Sobhy Zahran Jan 2024

Lupus Kidney Disease Spectrum And Characteristics Among Egyptian Adults And Children With Sle, Emad Mohammad Elshebiny, Simon Alphonse Botros, Mohamed Shokry Elharoun, Zeinab Abdelaziz Kasemy, Samar Tharwat Radwan, Enas Sobhy Zahran

Menoufia Medical Journal

Objective: This research aimed to study the renal involvement among adults and children with systemic lupus erythematosus. Background: In addition to the glomerular affection "lupus Nephritis"(LN), there are other forms of lupus kidney disease; tubulointerstitial nephritis (TIN); vascular disease; and drug-induced renal disease can be found in Systemic Lupus Erythematosus (SLE) patients. Patient and Methods: A cross-sectional hospital-based study was conducted on 100 SLE patients (74 adults and 26 children) with presumed renal involvement. Patients were assessed clinically and by laboratory tests for renal involvement and renal biopsy findings were recorded to classify renal affection stage and type. Results: Clinically …


Low Inguinal Microsurgical Varicocele Ligation Versus Conventional Inguinal Approach: Prospective Comparison Of Reproductive And Functional Outcomes, Ahmed Gamal El Din, Ahmed Moustafa Barsim, Mohamed Marzouk Abdallah, Eid Abdel Rasol El-Sherif Jan 2024

Low Inguinal Microsurgical Varicocele Ligation Versus Conventional Inguinal Approach: Prospective Comparison Of Reproductive And Functional Outcomes, Ahmed Gamal El Din, Ahmed Moustafa Barsim, Mohamed Marzouk Abdallah, Eid Abdel Rasol El-Sherif

Menoufia Medical Journal

Objectives: to evaluate the effectiveness and complications rates after microsurgical varicocele ligation in comparison to conventional inguinal approach. Methods: This study was a clinical randomized trial done in Menoufia Urology Department including eighty-three patients with varicocele from December 2018 to December 2020. Patients with clinical varicoceles and affected semen parameters were randomized to either conventional or microsurgical inguinal varicocelectomy. Intraoperative and post-operative complications were documented including hydrocele formation, varicocele recurrence, and testicular atrophy. Semen analysis was repeated after 3 months from date of surgery and compared to the pre-operative one. Results: Semen parameters improved significantly after varicocelectomy in both groups …


Urodynamic And Ultrasonic Findings After Anterior Vaginal Wall Prolapse Repair In Stress Urinary Incontinence, Mahy N. Egiz, Mohammed A. Elsayed, Mohammed A. Elshazly, Alaa M. Gomaa, Mohammed W. Abdelaziz Jan 2024

Urodynamic And Ultrasonic Findings After Anterior Vaginal Wall Prolapse Repair In Stress Urinary Incontinence, Mahy N. Egiz, Mohammed A. Elsayed, Mohammed A. Elshazly, Alaa M. Gomaa, Mohammed W. Abdelaziz

Menoufia Medical Journal

Objectives: To detect changes in ultrasound and urodynamic study in patients with stress urinary incontinence. Background: Assessment of urinary bladder neck mobility as part of assessment of SUI can be done by ultrasonography. It can be done through assessing urethral angles and bladder neck descent distance has for objective documentation of anatomical and functional parameters of the pelvic floor before and after surgery. Methods: a prospective longitudinal study was done on three groups of patients, first group included 16 cases of normal healthy individuals as control, the second group included 16 cases with anterior vaginal wall prolapse complicated by SUI, …


Major Incidental Findings In Ct Chest During Covid 19 Outbreak, Mohamed Basiony Alghannam, Amira Shawky Abdelhakim Eissa, Rehab Mohammed Habib Jan 2024

Major Incidental Findings In Ct Chest During Covid 19 Outbreak, Mohamed Basiony Alghannam, Amira Shawky Abdelhakim Eissa, Rehab Mohammed Habib

Menoufia Medical Journal

Objective: The objective of this study was to evaluate the role of multidetector computed tomography (CT) in the detection of major incidental findings of COVID 19 patients and to detect their clinical importance. Background: The outbreak of COVID-19 has caused concerns globally. On 30 January WHO has declared it as a global health emergency. Chest CT has a potential role in the diagnosis of coronavirus disease 2019 (COVID-19). Parenchymal and extra parenchymal incidental findings were detected and defined as any finding in the report not related to the purpose of the scan. Incidental findings on chest CT may represent highly …


Immunohistochemical Expression Of Heparanase Ii In Non-Melanoma Skin Cancer, Ola A. Elbakry, Mohamed A. Shoeib, Menna A. Abdelmonsif, Marwa M. Dawoud Jan 2024

Immunohistochemical Expression Of Heparanase Ii In Non-Melanoma Skin Cancer, Ola A. Elbakry, Mohamed A. Shoeib, Menna A. Abdelmonsif, Marwa M. Dawoud

Menoufia Medical Journal

Background: Heparan sulphate is present in the extracellular matrix of the skin. Heparanase is implicated in cellular invasion related to inflammation, cancer metastasis and angiogenesis. Heparanase II may inhibit heparanase activity by competing for the HS substrate. Heparanase II regulates selected genes that promote normal differentiation, endoplasmic reticulum stress, tumor fibrosis, and apoptosis, together resulting in tumor suppression. Aim: to investigate the involvement of heapranase II in non-melanoma skin cancer (NMSC) pathogenesis. Materials and Method: This study was carried out on a total number of 60 subjects, 30 cases with NMSC [15 cases with BCC and 15 cases with SCC] …


Role Of Neutrophil- Lymphocytic Ratio And Prognostic Nutritional Index After Transarterial Chemoembolization In Hepatocellular Carcinoma, Ayman M. El Lehleh, Shaimaa A. Hassanein, Mohamed A. Attya, Moamena S. El-Hamouli Jan 2024

Role Of Neutrophil- Lymphocytic Ratio And Prognostic Nutritional Index After Transarterial Chemoembolization In Hepatocellular Carcinoma, Ayman M. El Lehleh, Shaimaa A. Hassanein, Mohamed A. Attya, Moamena S. El-Hamouli

Menoufia Medical Journal

Objective: To evaluate the role of combined preoperative neutrophil lymphocytic ratio (NLR) and Prognostic nutritional index (PNI) as a predictor of the postoperative outcomes of unresectable Hepatocellular carcinoma (HCC) TACE-treated patients. Background: NLR and PNI are immunonutritional indices associated with postoperative outcomes in HCC TACE-treated patients. Patients and methods: NLR-PNI score calculated for 40 candidates and classified into 3 groups (NLR-PNI0, NLR-PNI1 and NLR-PNI2). Patients underwent TACE and investigations repeated after one month. Results: 22(100%) in NLR-PNI0 and 6(60%) in NLR-PNI1 had well ablated tumour. 4(40%) in NLR-PNI1 with residual tumour. All 8(100%) in NLR-PNI2 with largest sizes (8.64 ± …


Ketogenic Diet, Caloric Restriction And Intermittent Fasting Increase The Mitochondrial Activity In Aged Rats, Mohamed H.A. Hassan, Hesham A.D. Abdel-Razek, Yahya M. Naguib, Eman A. Badr, Sara E. Abdou, Ahmed M. Gaafar Jan 2024

Ketogenic Diet, Caloric Restriction And Intermittent Fasting Increase The Mitochondrial Activity In Aged Rats, Mohamed H.A. Hassan, Hesham A.D. Abdel-Razek, Yahya M. Naguib, Eman A. Badr, Sara E. Abdou, Ahmed M. Gaafar

Menoufia Medical Journal

Objective: Studying the effect of multiple dietary strategies on mitochondrial activity of aged rats. Background: Healthy aging may be achieved by intermittent fasting, caloric restriction or ketogenic diet regimens. Material and methods: Thirty-two male Wistar rats, 20-22-week-old, were randomized into four equal groups: control, ketogenic diet (KD), caloric restriction (CR) and intermittent fasting (IF) groups. After 8 weeks, rats were weighed, and subjected for measurement of systolic blood pressure (SBP) using a rat-tail sphygmomanometer, and neurobehavioral assessment via open field examination. Then, fasting retro-orbital blood samples were collected to measure free fatty acids (FFA), liver and kidney function tests and …


Role Of Point Of Care Ultrasonography In Acute Kidney Injury At Emergency Department, Hatem M. Sultan, Ahmed M. Zahran, Karem E.R Lashen, Mohamed F. Tantawy Jan 2024

Role Of Point Of Care Ultrasonography In Acute Kidney Injury At Emergency Department, Hatem M. Sultan, Ahmed M. Zahran, Karem E.R Lashen, Mohamed F. Tantawy

Menoufia Medical Journal

Background: Acute Kidney Injury (AKI) poses a critical challenge in emergency care, necessitating efficient diagnostic tools. This prospective study evaluates the diagnostic efficacy of Point-of-Care Ultrasound (POCUS) in AKI management, considering sociodemographic, clinical, and laboratory characteristics.

Objectives: To assess the role of pocus in the form of combining IVC Ultrasonography and renal ultrasonography to guide the assessment and management of patient presented with AKI in the Emergency department.

Methods: Ninety-two participants in the Emergency Department with Acute kidney Injury (AKI) underwent comprehensive assessments, including history taking, sociodemographic and clinical data, laboratory investigations and POCUS. Preliminary diagnosis of cause of …


Stature Estimation Using Different Upper Limb Anthropometric Measurements, Naira Fahmi Girgis, Amira Mohammed Elseidy, Maha Salah Elnady Afify, Shaimaa Abdel-Hamid Hassanein, Shireen Ragab Slima Jan 2024

Stature Estimation Using Different Upper Limb Anthropometric Measurements, Naira Fahmi Girgis, Amira Mohammed Elseidy, Maha Salah Elnady Afify, Shaimaa Abdel-Hamid Hassanein, Shireen Ragab Slima

Menoufia Medical Journal

Objectives: to analyze percutaneous and radiographic measurements of some upper limb parameters (ulna and hand) and their relationship to stature via the use of statistical analysis in an Egyptian sample, Menoufia governorate.

Background: Identification is the process of identifying a person, based on specific characteristics which differentiate him from other individuals. One key components of a person's identity is their stature. As there is a significant relationship between the dimensions of various body parts and stature, particularly bone lengths, estimating stature using long bone measurements provides an essential tool in the identification of unknown remains.

Methods: The cross-sectional study was …


Study Of The Different Modalities For Scrotal Skin Reconstruction, Mohamed Ahmed Megahed, Ahmed Tharwat Nassar, Khaled Mohamed Albassam, Qutaibah Alkandari, Ahmed Fergany Saber, Mina Safwat Zaki Jan 2024

Study Of The Different Modalities For Scrotal Skin Reconstruction, Mohamed Ahmed Megahed, Ahmed Tharwat Nassar, Khaled Mohamed Albassam, Qutaibah Alkandari, Ahmed Fergany Saber, Mina Safwat Zaki

Menoufia Medical Journal

Objectives: to study different modalities of reconstruction of defects in the scrotum and to verify indications and efficacy of each technique. Background: Techniques of genital reconstruction continue to evolve. However, mainstays of therapy include split-thickness skin graft, primary closure, and musculocutaneous flap. The best cosmetic and functional outcomes appear to occur in patients being treated for local cutaneous and lymphatic conditions. Methods: A prospective cross-sectional study was conducted on thirty male patients with a defect of scrotal skin with age range between 20 and 70 years old. They attended the plastic surgery and burn department of Menoufia University during the …


Assessment Of The Pattern, Management And Outcomes Of Acute Unstable Poisoning Patients In Emergency Department Of Menoufia University Hospitals., Ahmed Kamal Eldin Elfeky, Ahmed Sabry Elgamal, Mohammed Abdo Etman, Mai Saied Abdelmonem Khalifa, Athar Fekry Lasheen Jan 2024

Assessment Of The Pattern, Management And Outcomes Of Acute Unstable Poisoning Patients In Emergency Department Of Menoufia University Hospitals., Ahmed Kamal Eldin Elfeky, Ahmed Sabry Elgamal, Mohammed Abdo Etman, Mai Saied Abdelmonem Khalifa, Athar Fekry Lasheen

Menoufia Medical Journal

Objectives: To evaluate the pattern, management and outcomes of acute unstable poisoning cases at the emergency department of Menoufia University Hospitals. Background: Drug overdose is a medico-social issue worldwide that may occur intentionally or unintentionally. It is one of the most common reasons for emergency department visits, and it is also a frequent cause of morbidity and mortality globally. Methods: This was prospective study performed in the Emergency department of Menoufia University hospital. It was carried out on 84 patients triaged to the resuscitation room with toxicological history from March 2022 to March 2023. Full history including personal data, circumstances, …


Study Of Depression, Anxiety And Sleep Quality As Possible Predictors Of Fatigue In Regular Hemodialysis Patients, Ahmed Mosad Hassen, Ahmed Mohamed Zahran, Yassein Salah Yassein, Zeinab Abdelaziz Kasemy, Ahmed Saber El-Ghorieb Jan 2024

Study Of Depression, Anxiety And Sleep Quality As Possible Predictors Of Fatigue In Regular Hemodialysis Patients, Ahmed Mosad Hassen, Ahmed Mohamed Zahran, Yassein Salah Yassein, Zeinab Abdelaziz Kasemy, Ahmed Saber El-Ghorieb

Menoufia Medical Journal

Objectives: To assess the prevalence of depression, anxiety and quality of sleep and their relation to increased fatigue scores among patients on chronic hemodialysis. Background: Fatigue is one of the most common endured symptoms by hemodialysis patients, it’s usually unrecognized, untreated and remains complex phenomenon, factors may be attributed to fatigue include demographic, psychological, physiological factors, sleep disorders and dialysis inadequacy. Methods: A cross-sectional study was conducted on 82 patients receiving maintenance hemodialysis at Menoufia University Hospitals from November 2022 till December 2023, Demographic, clinical, laboratory data and clinical questionnaires were recorded for each patient. Results: Prevalence of fatigue, depression, …


Epidemiology And Clinical Features Of Immune Mediated Uveitis In Menoufia Population, Enas Sobhy Zahran, Emad Mohammed El-Shebiny, Eman Abdelfatah Shoker, Adel Galal Zaky, Emad Eldin Mohamed Elgemai Eldomuhy, Hadeer Ramadan Morshedy Mashal, Amr Hawash Jan 2024

Epidemiology And Clinical Features Of Immune Mediated Uveitis In Menoufia Population, Enas Sobhy Zahran, Emad Mohammed El-Shebiny, Eman Abdelfatah Shoker, Adel Galal Zaky, Emad Eldin Mohamed Elgemai Eldomuhy, Hadeer Ramadan Morshedy Mashal, Amr Hawash

Menoufia Medical Journal

Objectives: to determine the epidemiology and clinical features of immune mediated uveitis and to assess risk factors of Uveitis and to clarify diseases associated with Uveitis (AU).

Background: AU is a group of intraocular inflammatory diseases characterized by inflammation of the uvea and other tissues in the eye, including retina, retinal blood vessels, vitreous, and optic nerve. AU is a leading cause of blindness worldwide and accounts for 10–15% of vision loss worldwide.

Methods: A cross-sectional study was conducted at the outpatient department of Rheumatology division of Internal Medicine and department of ophthalmology at Menoufia University Hospitals. Written and informed …


Jak2 And Ptprc Mrna Expression Levels In Ankylosing Spondylitis And Systemic Lupus Erythematosus Patients, Yasser As El Ghobashy, Ibrahim Elmadbouh, Dina Salem Fotoh, Enas Subhi Zahran, Asmaa Mahmoud Shukry, Sherin Sobhy El Naidany Jan 2024

Jak2 And Ptprc Mrna Expression Levels In Ankylosing Spondylitis And Systemic Lupus Erythematosus Patients, Yasser As El Ghobashy, Ibrahim Elmadbouh, Dina Salem Fotoh, Enas Subhi Zahran, Asmaa Mahmoud Shukry, Sherin Sobhy El Naidany

Menoufia Medical Journal

Objectives: to evaluate RNA expression levels of Janus Kinase 2 (JAK 2) and protein tyrosine phosphatase receptor type C (PTPRC) genes in SLE and AS and correlate them with the severity of the two diseases. Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder with a wide range of clinical symptoms. Ankylosing spondylitis (AS) is an autoimmune inflammatory disease of young adult, affecting the axial skeleton and articular joints. Methods: A case-control study included 96 subjects: (32 SLE patients, 32 AS patients, and 32 healthy control subjects). Differences in the expression levels of JAK2 and PTPRC in the blood of …


Role Of Surgery In The Prognosis Of Pediatric Thalamic Tumors, Mohamed Khaled Eissa, Mohamed Elbeltagy, Hesham Abou-Rahma, Hazem Mohamed Negm, Ahmed Said Mansour, Yasser Bahgat Elsisi Jan 2024

Role Of Surgery In The Prognosis Of Pediatric Thalamic Tumors, Mohamed Khaled Eissa, Mohamed Elbeltagy, Hesham Abou-Rahma, Hazem Mohamed Negm, Ahmed Said Mansour, Yasser Bahgat Elsisi

Menoufia Medical Journal

Objective: This study aimed to present the authors' experience in managing 20 cases of pediatric thalamic brain tumors. Background: Thalamic tumors constitute a small percentage (approximately 0.84-5.2%) of all brain tumors and are even rarer in the pediatric population, accounting for about 2-5% of pediatric brain tumors. These tumors present a significant challenge to neurosurgeons due to their intricate location within the brain and their proximity to crucial structures, especially in children. The management of these tumors necessitates careful consideration and expertise due to the potential risks associated with their critical position. Patients and Methods: In this retrospective study, the …


Study And Clinical Significance Of Urinary Levels Of Glypican 5 In Diabetic Patients, Nabil A. El-Kafrawy, Ahmed O. Talaat, Moustafa B. Ata Jan 2024

Study And Clinical Significance Of Urinary Levels Of Glypican 5 In Diabetic Patients, Nabil A. El-Kafrawy, Ahmed O. Talaat, Moustafa B. Ata

Menoufia Medical Journal

Objective: To evaluate the urinary GPC5 level in T2DM as an early marker for DN. Background: Diabetic nephropathy (DN) is one of the most serious long-term consequences of type 2 diabetes mellitus (T2DM) because it causes end-stage renal disease. Methods: This cross-sectional study was done on 90 individuals, classified equally into three groups: Group 1: T2DM patients with DN, group 2: T2DM patients without DN and group 3: healthy controls without DM. They underwent [serum creatinine (sCr), serum glycated haemoglobin (HbA1c), urinary albumin to creatinine ratio (ACR), estimated glomerular filtration rate (eGFR), total cholesterol (TC), high density lipoproteins (HDL), low …


Amniotic Fluid Level Effect On The Accuracy Of Sonographic Estimated Fetal Weight At Term, Mohamed Elsibai Anter, Sayed Abdel-Moneim Mahmoud, Alaa Eldeen Fathallah El-Halaby, Mohamed Shawky Abdullah, Eslam Omar Yosre Elsarrag Jan 2024

Amniotic Fluid Level Effect On The Accuracy Of Sonographic Estimated Fetal Weight At Term, Mohamed Elsibai Anter, Sayed Abdel-Moneim Mahmoud, Alaa Eldeen Fathallah El-Halaby, Mohamed Shawky Abdullah, Eslam Omar Yosre Elsarrag

Menoufia Medical Journal

Objective: to study amniotic fluid index (AFI) effect on estimated fetal weight (EFW) measurement accuracy at term. Background: amniotic fluid assessment by ultrasound at full term is an essential factor of the fetal biophysical profile and confirm fetal well-being. Method: we conducted a prospective cohort study on 129 medically free pregnant women divided into three groups according to AFI with ratio 1:1:1: oligohydramnios group (43 cases AFIcm), polyhydramnios group (43 cases AFI>24 cm) and cases had normal volume of amniotic fluid (43 cases AFI between 5 cm and 24 cm). Results: we found highly significant difference among studied groups …


What Is The Ideal Free Flap For Microvascular Lower Limb Soft Tissue Reconstruction?, Mohamed Abdallah Elnahas, Abdallah Ahmad Amin, Fouad Mohamed Ghareeb, Hassam Hassan Fawzy Jan 2024

What Is The Ideal Free Flap For Microvascular Lower Limb Soft Tissue Reconstruction?, Mohamed Abdallah Elnahas, Abdallah Ahmad Amin, Fouad Mohamed Ghareeb, Hassam Hassan Fawzy

Menoufia Medical Journal

Objectives: is to detail four reliable free flaps including the anterolateral thigh, radial forearm, thoracodorsal and latissimus dorsi for use in lower extremity microvascular reconstruction and to establish factors to consider when developing an algorithm for reconstructing lower extremity injuries. Background: to achieve restoration of normal functions and good aesthetic outcomes ; microvascular free flaps are the preferred method for complex injuries repair in lower limbs. Methods: A total of 30 patients with complex soft tissue lower limb defects and deformities required surgical reconstruction were enrolled in this study. They underwent four types of free flap reconstruction. All patients were …


Outcome Of Combined Or Single Flexor Digitorum Superficialis And Flexor Digitorum Profundus Repair In Zone Ii, Mayadah Adel Nossir, Dalia Mofreh Elsakka, Hady Saleh Abou-Ashour, Mohamed Abdallah Elnahas Jan 2024

Outcome Of Combined Or Single Flexor Digitorum Superficialis And Flexor Digitorum Profundus Repair In Zone Ii, Mayadah Adel Nossir, Dalia Mofreh Elsakka, Hady Saleh Abou-Ashour, Mohamed Abdallah Elnahas

Menoufia Medical Journal

Objectives: To evaluate the outcomes of the repair of flexor digitorum Profundus (FDP) alone versus its repair combined with flexor digitorum superficialis (FDS) repair in Zone II flexor tendon injury. Background: Flexor tendon injuries in zone II of the hand present a challenging problem for hand surgeons. Injuries involving the FDP and FDS tendons require careful assessment and planning. The primary goals of repair are to achieve optimal tendon healing, maximize range of motion, and restore functional strength. Methods: A total of 24 patients presenting with FDP and FDP injury at zone II were surgically treated from 2020 to 2022. …


Association Between Tspan15 (Rs78707713) And Slc44a2 (Rs2288904) Genetic Polymorphisms And Venous Thromboembolism In Cancer Patients, Shaimaa El Sayed Ramadan Genena, Alshimaa Mahmoud Alhanafy, Suzan Foad Omar, Manal Monir Mansour, Mona Abdelhamid Mohammed Kora, Mohamed Abdelhafez, Marwa Mohammed Ibrahim Mohammed Khalil Jan 2024

Association Between Tspan15 (Rs78707713) And Slc44a2 (Rs2288904) Genetic Polymorphisms And Venous Thromboembolism In Cancer Patients, Shaimaa El Sayed Ramadan Genena, Alshimaa Mahmoud Alhanafy, Suzan Foad Omar, Manal Monir Mansour, Mona Abdelhamid Mohammed Kora, Mohamed Abdelhafez, Marwa Mohammed Ibrahim Mohammed Khalil

Menoufia Medical Journal

Objectives: to assess the relationship between TSPAN15 and SLC44A2 polymorphisms and VTE in cancer patients was evaluated with correlation to PROTECHT scoring system and survival data. Background: Although venous thromboembolism (VTE) is common in cancer patients, the underlying mechanisms are complex and poorly understood. .Methods: This study enrolled two groups: 50 VTE-cancer patients in group I and 50 cancer patients with no VTE in group II. Full history, general examination, histopathological diagnosis, and clinical stage were recorded. Complete blood count, coagulation profile, and analysis of TSPAN15 (rs78707713) and SLC44A2 (rs2288904) SNPs by polymerase chain reaction technique were done. Radiological examinations …


Treatment Of Post-Burn Hypopigmentation With Non-Cultured Epidermal Grafting, Islam Ibrahim Abd Elmohsen, Ahmed Tharwat Nassar, Tarek Fouad Kishk, Ahmed Fergany Saber, Hossam Hassan Fawzy Jan 2024

Treatment Of Post-Burn Hypopigmentation With Non-Cultured Epidermal Grafting, Islam Ibrahim Abd Elmohsen, Ahmed Tharwat Nassar, Tarek Fouad Kishk, Ahmed Fergany Saber, Hossam Hassan Fawzy

Menoufia Medical Journal

Objectives: To evaluate the applicability of cell therapy using non-cultured epidermal transplantation regarding the aesthetic outcome, , and possible complications in the treatment of post-burn hypopigmentation. Background: new non-cultured autologous epidermal techniques have been developed with similar results to the cultured melanocytes techniques, but are simpler, less expensive, and less time-consuming. Methods: This prospective study was conducted on 35 post-burn hypopigmentation patients presented at the Plastic and Reconstructive Surgery Department in Menoufia University Hospitals between April 2020 to April 2023. Results: We found that the repigmentation ranged between 20-95%, and the color matching ranged between 30-80%. Most cases had good …


Patients’ Expectations Before Coronary Artery Bypass Graft Surgery: A Cross- Sectional Study, Mohammad Abdallah, Shymaa Mamdouh Mohamed Abdu Sh.M, Abdel-Hady El-Gilany Ah.G, Wael Abdel-Aziz, Noha Eladawy, Olfat Farag Jan 2024

Patients’ Expectations Before Coronary Artery Bypass Graft Surgery: A Cross- Sectional Study, Mohammad Abdallah, Shymaa Mamdouh Mohamed Abdu Sh.M, Abdel-Hady El-Gilany Ah.G, Wael Abdel-Aziz, Noha Eladawy, Olfat Farag

Menoufia Medical Journal

Background

Exploring patient’ s expectations before coronary artery bypass graft (CABG) surgery provides clinicians with important insights into their service population.

Objectives

The objective of this study is to describe the expectations of patients before CABG surgery and its associated factors.

Patients and methods

A cross-sectional study was conducted in the Outpatient Clinic of an Egyptian Cardiac Surgery Unit during the period from May 2017 to April 2018. A total of 446 patients who underwent CABG surgery were included. The socio-demographic and clinical data were collected from patients and their medical records. The Cardiac Surgery Patient Expectations questionnaire was used …