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Inflammatory Bowel Disease Diagnosis Using Metagenomic Classification, Michael Riggle Apr 2020

Inflammatory Bowel Disease Diagnosis Using Metagenomic Classification, Michael Riggle

Masters Theses & Specialist Projects

Inflammatory bowel disease (IBD) is a set of disorders that involve chronic inflammation of digestive tracts, e.g., Crohn's disease (CD) and ulcerative colitis (UC). Millions of people around the world have inflammatory bowel disease. However, it is still difficult to treat IBD due to its unknown cause. In fact, accurately diagnosing inflammatory bowel disease (IBD) can be very challenging too since some of IBD symptoms can mimic those of other conditions. In this work, we apply classification methods to help improve the success rate of diagnosis. We study four formulations of IBD classification: i) IBD and non-IBD (binary classification), ii) …


Online Shoppers Spending On Fresh Produce; Do Those On Government Assistance Spend Less?, Wyatt Tucker Lucas Apr 2020

Online Shoppers Spending On Fresh Produce; Do Those On Government Assistance Spend Less?, Wyatt Tucker Lucas

Masters Theses & Specialist Projects

This study applies an Ordinary Least Squares (OLS) model to explain differences in the amount that online shoppers might spend per month on fresh produce, given specific consumer characteristics. It also uses a multinomial logit model to determine the relative probability of online shoppers spending more or less, given specific consumer characteristics. The independent variable of interest in both models is whether or not the respondent is a recipient of a government assistance food program. These analyses used data from a stratified random sample of 1,205 online shoppers residing in the southern region of the United States. “Online shoppers” in …


Morphology And Structure Of Pb Thin Films Grown On Si (111) By Pulsed Laser Deposition, Bektur Abdisatarov Apr 2020

Morphology And Structure Of Pb Thin Films Grown On Si (111) By Pulsed Laser Deposition, Bektur Abdisatarov

Masters Theses & Specialist Projects

Pulsed laser deposition (PLD) is a versatile thin film deposition technique in which high powered laser beam interacts with a target material inside an ultrahigh vacuum chamber. Highly energetic particles such as electrons, atoms, protons, and ions generate a plasma plume that directed towards a substrate material where recondenses form a thin film. PLD is an effective and reliable method to create varieties of thin films such as metal, polymer, and ceramic for many technologically essential applications.

In this study, thin Pb films were grown by pulsed laser deposition on Si (111) at various laser fluences, pulse wavelengths, deposition times, …


Monitoring And Identifying The Rhodamine 6g-Hydroxide Ion Reaction Using In-Situ, Surface-Enhanced Raman Spectroscopy, Ryan Lamb Apr 2020

Monitoring And Identifying The Rhodamine 6g-Hydroxide Ion Reaction Using In-Situ, Surface-Enhanced Raman Spectroscopy, Ryan Lamb

Masters Theses & Specialist Projects

An effective method for monitoring chemical reactions is necessary to better understand their mechanisms and kinetics. Effective reaction monitoring requires a spectroscopy technique with fast data acquisition, high sensitivity, structure-to-spectrum correlation, and low solvent interference. Surface-enhanced Raman spectroscopy (SERS) provides these features, which makes it a valuable tool for monitoring reactions. To obtain the Raman enhancement, metallic nanostructures typically made of silver or gold are aggregated using a salt. The nanoparticles aggregates must then be stabilized using a surfactant to use this method in situ due to eventual nanoparticle precipitation. In this study, gold nanoparticles stabilized with sodium dodecyl sulfate …


Bodyweight Management And Relationship To Health In The Horse (Equus Caballus), Beverly Ann Gartland Apr 2020

Bodyweight Management And Relationship To Health In The Horse (Equus Caballus), Beverly Ann Gartland

Masters Theses & Specialist Projects

The health of the horse is of interest to animal caretakers. Horses that fall within a prescribed range of bodyweight and body condition may be healthier than horses that are lower or higher. Two studies were conducted related to body weight and condition of the horse. The first study examined if restricting the amount of space available for horses to graze could reduce bodyweight without having a strong impact on time budgets of the horse or removing horses from pasture. This method was determined to be effective in preventing weight gain, although there was an increase in grazing behavior displayed …


The Common Man And The Rise Of The Anabaptist Kingdom Of Munster, 1534-1535, Andrew Roebuck Apr 2020

The Common Man And The Rise Of The Anabaptist Kingdom Of Munster, 1534-1535, Andrew Roebuck

Masters Theses & Specialist Projects

This essay studies the causes of the rise of the Anabaptist Kingdom of Munster, with special emphasis on the actions and agency of the common people. The analysis begins with the two main primary sources, Hermann von Kerssenbrock and Henry Gresbeck, whose accounts provide firsthand knowledge of how events in Munster led to the Anabaptist takeover. Care is taken to read beyond some of the biases and assumptions made by those authors to gain the clearest insight for what really happened.

The essay looks at Anabaptism itself, including what it meant to be Anabaptist from the perspectives of participants and …


The Predictive Validity Of Star Early Literacy, Karlissa Pollack Apr 2020

The Predictive Validity Of Star Early Literacy, Karlissa Pollack

Masters Theses & Specialist Projects

In recent years, paper-and-pencil screenings have, to a degree, given way to computer adaptive tests as a more effective way to screen students, though some measures lack research in regards to their utility. The utility of Star Early Literacy (SEL) for predicting future state test performance was examined by analyzing student performance on SEL and student performance on state testing two years later. The following research questions were examined: What is the relationship among first grade SEL scores and performance on the third grade reading state test? What is the diagnostic accuracy of SEL for predicting reading state test performance …


Interdependence Across Foreign Exchange Rate Markets- A Mixed Copula Approach, Richard Adjei-Boateng Apr 2020

Interdependence Across Foreign Exchange Rate Markets- A Mixed Copula Approach, Richard Adjei-Boateng

Masters Theses & Specialist Projects

The purpose of this thesis is to study the dependence structure of exchange rate pairs using a mixture of copula as opposed to a single copula approach. Mixed copula models have the ability to generate dependence structures that do not belong to existing copula families. The flexibility in choosing component copulas in this mixture model aids the construction of a system that is simultaneously parsimonious and flexible enough to generate most dependence patterns in exchange rate data. Furthermore, the method of mixture copulas facilitates the separation of both the structure and degree of dependence, concepts that are respectively embodied in …


Delineation Of Undescribed, Morphologically Cryptic Cave Beetles Of The Pseudanophthalmus Pubescens Species-Group (Coleoptera: Carabidae: Trechinae), Jedidiah John Nixon Apr 2020

Delineation Of Undescribed, Morphologically Cryptic Cave Beetles Of The Pseudanophthalmus Pubescens Species-Group (Coleoptera: Carabidae: Trechinae), Jedidiah John Nixon

Masters Theses & Specialist Projects

The genus Pseudanophthalmus Jeannel is a widespread and extremely diverse taxon of troglobiont beetle endemic to the karst of eastern North America, with its distribution centered in Tennessee and Kentucky. Despite lying near the heart of this region, the pubescens species-group was thought to contain many undescribed species. In this study, the validities of several of the late Dr. Thomas Barr’s unpublished putative new species in the pubescens-group were tested both morphologically and molecularly. Body measurements (length and width for head, thorax, and abdomen), as well as male genital morphology were compared to see if they reflected theorized species limits.. …


Tell Me What You Need: An Examination Of Dialectical Tensions Within Romantic Relationships With Depressed Partners, Leah Christine Goodwin Apr 2020

Tell Me What You Need: An Examination Of Dialectical Tensions Within Romantic Relationships With Depressed Partners, Leah Christine Goodwin

Masters Theses & Specialist Projects

While depression communication in romantic relationships has been heavily studied in psychological-based research, there is a lack of research grounded in communication theory. By using Relational Dialectics Theory (RDT) as a framework, communicative tensions and coping strategies were explored within relationships where one partner suffered from depression. Through eleven semi-structured interviews with both depressed and non-depressed individuals in a relationship, three major dialectical tensions and two major maintenance strategies emerged. Findings suggest that couples with a depressed partner faced unique and challenging tensions including involvement/distance, openness/closedness, and revelation/concealment. A number of positive and negative coping strategies for managing the tensions …


Reliability And Validity Of An Assessment Of Engagement In Nursing Home Residents During Bingocize®, Elizabeth Batson Apelt Apr 2020

Reliability And Validity Of An Assessment Of Engagement In Nursing Home Residents During Bingocize®, Elizabeth Batson Apelt

Masters Theses & Specialist Projects

Research suggests nursing home residents are often socially isolated and physically inactive despite overwhelming evidence that both social engagement and physical activity are crucial for healthy aging (Jones, Sung, & Moyle, 2018; Yen & Lin, 2018; Ice, 2002; Jansson et al., 2017). Bingocize® is a program that combines exercise and the game of Bingo to improve the quality of life, physical health, and social engagement of certified nursing facility (CNF) residents. The purpose of this study is to determine the level of social engagement displayed by CNF residents during Bingocize® using the Fun and Social Engagement Evaluation (FUSE). Reliability and …


Does Infant Temperament And Parental Involvement Influence Infant Cardiac Physiological Regulation?, Mary Richter Apr 2020

Does Infant Temperament And Parental Involvement Influence Infant Cardiac Physiological Regulation?, Mary Richter

Masters Theses & Specialist Projects

The ability to self-regulate allows infants to stay at a baseline level during periods of stress (Porges, 1995). Baseline respiratory sinus arrhythmia (RSA) may be used as an indicator of self-regulation and how well an individual can respond to changes in the environment (Stifter & Corey, 2001). Differences in infant temperament can influence a child’s ability to self-regulate (Dale et al., 2011), but moderators of this relationship have not been thoroughly examined in the literature. Parents who are more involved might have more opportunities to teach children important regulatory strategies (Blandon et al., 2010). The current study examined the association …


Reliability Of Index And Subtest Discrepancy Scores From The Kabc-Ii Nu, Grant Hacherl Apr 2020

Reliability Of Index And Subtest Discrepancy Scores From The Kabc-Ii Nu, Grant Hacherl

Masters Theses & Specialist Projects

School psychologists often consider index- and subtest-level discrepancy scores from intelligence tests when making decisions regarding students’ special education eligibility. Best practices for clinical decision-making indicate that scores may only be considered if they meet an established standard of reliability. Therefore, it is essential to assess whether an interpretation of discrepancy scores can be considered reliable. This research used data provided in the supplemental manual of the Kaufman Assessment Battery for Children, Second Edition Normative Update (KABC-II NU) to calculate internal reliability coefficients (ICR) for discrepancy scores for each of the sample age group batteries, ages 3-6 and ages 7-18. …


Working Memory And Study Strategies: Effects On Performance Gaps, Chloe Stearns Apr 2020

Working Memory And Study Strategies: Effects On Performance Gaps, Chloe Stearns

Masters Theses & Specialist Projects

Working Memory (WM) is a critical contributor to learning. Those with low WM (LWM) are frequently at a disadvantage compared to those with high WM (HWM). Effective study strategies like practice retrieval, and self-explanation have been found to increase retrieval performance. This study compared the use of effective strategies between those with HWM and LWM, to determine whether the effect of study strategies on verbatim, inference, and total retrieval test scores differed due to WM when effective strategies were provided. Results indicated no significant difference in strategy quality between those with HWM and LWM. When looking at retrieval performance, WM …


Improving Sustainability Using Cover Crop Grazing To Improve Soil Health And Fertility While Increasing Grain And Livestock Production, Kylie Paige Ewing Apr 2020

Improving Sustainability Using Cover Crop Grazing To Improve Soil Health And Fertility While Increasing Grain And Livestock Production, Kylie Paige Ewing

Masters Theses & Specialist Projects

Cover crops have become an increasingly popular option for alleviating agronomic and environmental concerns, such as erosion. Dual utilization can increase forage use efficiency and increase immediate economic return but understanding the impact on soil health and grain production may affect viability of this strategy. In a two year study conducted in Bowling Green, Kentucky, soil health was analyzed comparing three treatments: grazed wheat (Triticum aestivum; WGR) to un-grazed wheat (W) and grazed tall fescue (Festuca arundinacea; TF). Sixteen cow calf pairs were randomly allocated to grazed wheat or tall fescue for two weeks. Soil samples were analyzed following grazing …


Substrate-Borne Vibrational Communication In Veiled Chameleons (Chamaeleo Calyptratus) During Courtship, Breeding, And Territoriality, Lauren Kappel Apr 2020

Substrate-Borne Vibrational Communication In Veiled Chameleons (Chamaeleo Calyptratus) During Courtship, Breeding, And Territoriality, Lauren Kappel

Masters Theses & Specialist Projects

Substrate-borne vibrations, or biotremors, are utilized by vertebrates found in unique environments because biotremors are an effective way to transmit signals through dense media. Previous studies have shown that veiled chameleons (Chamaeleo calyptratus) are able to produce biotremors via specialized neck muscles. I hypothesized that during courtship and/or breeding, the veiled chameleon, a tree-dwelling species, would communicate with biotremors through branches. Additionally, I hypothesized that female call characteristics would differ between reproductive condition (i.e., receptive and non-receptive), while male call characteristics would differ between behavioral contexts (i.e., territorial vs. courtship). Chameleons were paired (one male, one female) and placed on …


Effects Of Pharmacologically-Induced Sleep Loss On Parental Care In Arctic-Breeding Songbirds, Wesley Payette Apr 2020

Effects Of Pharmacologically-Induced Sleep Loss On Parental Care In Arctic-Breeding Songbirds, Wesley Payette

Masters Theses & Specialist Projects

Sleep loss is well known to impair cognitive function, immunological responses, and general well-being in humans. However, sleep requirements in mammals and birds may vary dramatically, especially with changes in environment. In circumpolar regions with continuous light, sleep requirements may be little, particularly in breeding birds. The effects of sleep loss on several fitness parameters were examined in two species of Arctic-breeding passerine birds: Lapland longspurs (Calcarius lapponicus) and snow buntings (Plectrophenax nivalis). Adult males were implanted during the nestling phase (4 days post-hatch) with osmotic pumps containing an anti-narcolepsy drug, modafinil, to extend the active period for 72 h. …


Western Kentucky University Psychological Sciences Faculty Bars Revision, Brian Coyne Apr 2020

Western Kentucky University Psychological Sciences Faculty Bars Revision, Brian Coyne

Masters Theses & Specialist Projects

In any organization, universities included, the development of quality personnel to perform work is of paramount importance. Thus, the ability to identify individual employee strengths and weaknesses and provide constructive feedback is vital. In this thesis I discuss the strengths and weaknesses of various performance appraisal formats, before suggesting behaviorally anchored rating scales (BARS) as an optimal tool in evaluating the performance of university faculty. I discuss BARS development in depth, as well as highlight BARS strengths as a performance appraisal tool. I further outline the process used and results obtained in updating the BARS used in the performance evaluation …


Y Con Ellos Rezamos: The Intersection Of Spanish Religious Identity And Nationalism In The Valley Of The Fallen, 1939-2019, Helen Michelle Spalding Apr 2020

Y Con Ellos Rezamos: The Intersection Of Spanish Religious Identity And Nationalism In The Valley Of The Fallen, 1939-2019, Helen Michelle Spalding

Masters Theses & Specialist Projects

Nestled in the Sierra de Guadarrama mountains of Spain in northwest Madrid is The Valley of the Fallen, (El Valle de los Caídos). This Spanish Civil War monument was originally constructed in 1940 as a celebration of the fascist victory of the war over the radical leftist republicanos. The monument made clear the Catholic ties that dictator Francisco Franco’s regime planned to uphold through its religious spaces such as an abbey and basilica. Since the monument’s construction and into the present day, the public eye has mainly associated the Valley of the Fallen with the Francoist dictatorship. However, this paper …


Research Into Practice: Exploring Teacher Practices With Young Gifted Learners, Andrea Lauren Heming Apr 2020

Research Into Practice: Exploring Teacher Practices With Young Gifted Learners, Andrea Lauren Heming

Masters Theses & Specialist Projects

This research study investigates teacher practices with young gifted learners and provides recommendations to increase the effectiveness of the Primary Talent Pool through examination of the program as it is implemented in four Kentucky school districts. Gifted coordinators were interviewed and primary (kindergarten-third grade) teachers were surveyed. Though each school has different methods for meeting the needs of high potential learners, there are commonalities across all seven schools represented. The present findings indicate teachers feel confident in their ability to recognize high potential in academic areas. Teachers are comfortable using differentiation, and often differentiate to support gifted learners.


A Monte Carlo Analysis Of Thorndike's Indirect Range Restriction Correction Equations, Michael Thomas Pelayo Apr 2020

A Monte Carlo Analysis Of Thorndike's Indirect Range Restriction Correction Equations, Michael Thomas Pelayo

Masters Theses & Specialist Projects

Employee selection is an important process for organizations. Organizations seek to select the best employees for their available positions. Testing is key to many selection efforts. The results of studies assessing the criterion-related validity of a selection test are affected by a number of statistical artifacts, one of which is range restriction. Range restriction has the effect of attenuating the correlation coefficient. Statistical equations exist to correct for the effects of range restriction, and they enable researchers to obtain a more accurate estimate of the validity coefficient. Thorndike (1949) developed the best known and most frequently used of these correction …


Synthesis And Molecular Mechanics Study Of Platinum Triamine Complex With N-Acetyl-L-Methionine And Guanosine 5’Monophosphate, Nitin Tanajirao Katare Apr 2020

Synthesis And Molecular Mechanics Study Of Platinum Triamine Complex With N-Acetyl-L-Methionine And Guanosine 5’Monophosphate, Nitin Tanajirao Katare

Masters Theses & Specialist Projects

Cisplatin and its analogues have been used and tested over decades for cancer treatment, but because of the serious side effects, it is important to find ways to overcome those side effect by synthesizing a novel platinum molecule. We have synthesized triamine complex and conducted its reaction with biomolecules such as 5’GMP and Methionine in the lab as well as conducted molecular mechanics (MM). MM methods are used for predicting and designing new structures and properties, and to model geometries of small molecules. MM and dynamics calculations have been used to study the 9 Ethylguanine and N-Ac-Lmethionine complexes with platinum …


Is Physical Activity During Late Pregnancy Related To Infant Body Composition At Birth?, Brenna Menke Apr 2020

Is Physical Activity During Late Pregnancy Related To Infant Body Composition At Birth?, Brenna Menke

Masters Theses & Specialist Projects

Exercise is typically regarded as having a positive impact on maternal and infant health. However, the relationship between maternal physical activity and infant body composition is unclear. The aim of this project was to determine how a physically active lifestyle during late pregnancy influences infant anthropometrics at birth. Pregnant women (34-39 weeks gestation) with low-risk pregnancies were given the Pregnancy Physical Activity Questionnaire (PPAQ) and an accelerometer to wear on their non-dominant wrist for seven consecutive days. Approximately 24-48 hours after delivery, infant body composition was assessed utilizing air displacement plethysmography at the patients’ bedside. Fifty-five pregnant women participated (age: …


From Coalescence To Bureaucratization: Veganuary’S Use Of Rhetorical Strategies On Social Media, Sabrina A. Carr Apr 2020

From Coalescence To Bureaucratization: Veganuary’S Use Of Rhetorical Strategies On Social Media, Sabrina A. Carr

Masters Theses & Specialist Projects

Social movement plays an integral part in how our society makes progress and changes overtime. With the birth and adoption of digital technologies comes new and unique opportunities for social movements and social movement organizations to make further progress and accomplish its goals. This study uses the foundations of organizational identification and values advocacy to evaluate the rhetoric of a specific organization within the vegan movement, Veganuary, and shows how this organization utilizes various strategies on its social media platforms to grow as an organization over a six-year time period. Specifically, I argue that Veganuary was able to move from …


Families First: Impact On Parent Knowledge, And Association Between Program Quality And Child Symptom Severity, Cibrian Johnson Apr 2020

Families First: Impact On Parent Knowledge, And Association Between Program Quality And Child Symptom Severity, Cibrian Johnson

Masters Theses & Specialist Projects

The Families First parenting workshops were developed for caregivers of children recently diagnosed with autism spectrum disorder (ASD). The primary site hosts inperson workshops, but webcasts the workshops to remote sites in different areas of the United States. The purpose of this study was to assess whether parents have an increase in knowledge after participating in Families First workshops at a remote site, and to assess whether program quality ratings and child symptom severity are associated with parent knowledge. The current study addressed the following research questions:

1. Do parents participating in the Families First workshops at a remote site …


Toxicity Of Novel Platinum Compounds In Mammalian Cancer Cells, Vanesa Veletanlic Apr 2020

Toxicity Of Novel Platinum Compounds In Mammalian Cancer Cells, Vanesa Veletanlic

Masters Theses & Specialist Projects

There are currently three FDA platinum compounds approved for use as chemotherapeutics, where each drug has variable efficacies for different cancer types depending on cancer’s tissue of origin. The approved compounds are platinum(II) complexes with four coordination sites on the platinum atom allowing two types of ligands to attach: leaving ligands, which are removed from the platinum atom in solution, and non-leaving ligands, which remain complexed to the platinum. Carboplatin, the preferred compound used to treat ovarian and small-cell lung cancers, has a characteristic cyclobutanedicarboxylic acid leaving ligand and two ammonia non-leaving ligands. A novel compound, 1,1-cyclobutanedicarboxylato(ethylenediamine)platinum (II), or Pt(en)CBDCA, …


Students With Autism And Aggressive Behavior: A Review Of Evidence-Based Interventions, Alisha Kelsay Apr 2020

Students With Autism And Aggressive Behavior: A Review Of Evidence-Based Interventions, Alisha Kelsay

Masters Theses & Specialist Projects

Aggression can be present in students diagnosed with autism spectrum disorder (ASD), and may need to be considered within academic environments. Interventions that are evidence-based have been identified to assist educators with issues with aggression in students with ASD. This review of evidence-based interventions highlights the effectiveness and social validity within educational settings that may be useful to instructors and other educational staff. Teachers need to be equipped with interventions that are considered to be effective and easy to implement within the school system. The literature available about the evidence based interventions for students with ASD are limited when the …


Positive Behavior Intervention And Support: Barriers And Facilitators To Implementation, Kendall Blanche Jarboe Apr 2020

Positive Behavior Intervention And Support: Barriers And Facilitators To Implementation, Kendall Blanche Jarboe

Masters Theses & Specialist Projects

PBIS is a comprehensive prevention framework utilized in schools to teach positive, prosocial behaviors and to prevent problem behaviors from developing. Although PBIS has been introduced in many schools in the U.S., almost 75% of public schools have not yet implemented PBIS. Despite evidence suggesting PBIS improves behavior and academic achievement in students of all ages and is associated with positive long-term outcomes, many public schools still refrain from exploring implementation of school-wide or district-wide positive behavior supports (Reinke, Herman, & Stormont, 2013). In order to improve the efficiency and fidelity of implementation, it is imperative to understand the variables …


Reliability Of Index And Subtest Discrepancy Scores On The Wj-Iv Cognitive, Kacy Stinson Apr 2020

Reliability Of Index And Subtest Discrepancy Scores On The Wj-Iv Cognitive, Kacy Stinson

Masters Theses & Specialist Projects

Many guidebooks and publication manuals for intelligence tests recommend that practitioners calculate subtest and index level discrepancy scores along with many other types of scores. The reliability of the discrepancy scores, however, are not provided in the test manuals. The purpose of the study was to determine the reliability of the discrepancy scores in the Woodcock Johnson Test of Cognitive Abilities (WJ IV COG, 2014). Using data from the WJ IV technical manual, the reliability of the discrepancy scores were examined at both the subtest and index level. The results were compared to the reliability criteria recommended by the assessment …


"Woman Problems": Superior-Subordinate Communication Of Endometriosis, Mary Madison Lyons Apr 2020

"Woman Problems": Superior-Subordinate Communication Of Endometriosis, Mary Madison Lyons

Masters Theses & Specialist Projects

The purpose of this study is to understand how working women with endometriosis communicate with their superiors about their chronic health condition. An interpretative approach was taken through the use of semi-structured interviews. Data were analyzed by using a constant-comparison method of thematic coding, resulting in three themes that answered the research questions. The findings revealed that working women communicate about endometriosis with their superiors via a dialectical tension of openness and closedness. Women perceived the outcomes of disclosure positively and negatively, but the anticipated outcomes were highly prevalent. Relational closeness between superior and subordinate was a key factor in …