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Efficacy Of Δ-9-Tetrahydrocannabinol For Hiv-Related Neuropathic Pain, Kaia Horne May 2022

Efficacy Of Δ-9-Tetrahydrocannabinol For Hiv-Related Neuropathic Pain, Kaia Horne

Honors Theses

Despite the availability and success of antiretroviral therapeutics, ~30% of patients living with HIV experience neuropathic pain that is often intractable. The mechanisms are not known, but there is evidence to support a role for the HIV virotoxins, Tat and/or gp120, which can damage or degenerate neurons and peripheral nerves. One mechanism by which Tat and gp120 promote nerve damage involves the stimulation of proinflammatory cytokine production from immune cells which can damage or kill bystander cells. Notably, compounds found in Cannabis exert anti-inflammatory effects and many studies report HIV patients to consume more marijuana than seronegative individuals. When people …


The Green Wave: Effects Of Legal Marijuana On The Labor Market., Sara Varon Jan 2022

The Green Wave: Effects Of Legal Marijuana On The Labor Market., Sara Varon

Honors Theses

In this paper I examine the relationship between the introduction of recreational marijuana laws and the labor market. First, using Google Trends data I find evidence that states that undergo the treatment of recreational marijuana legalization will likely experience a large and significant increase in search volume terms related to marijuana demand following the implementation of marijuana regulations. Using this same data set, I find support for the theory that as marijuana legalization becomes more entrenched within each individual state, public interest for marijuana also increases which allows for the use of Google Trends data as a proxy for legalization …