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Conformationally-Controlled Late-Stage Modifications For Sar Studies Of The C-3-Glcp Moiety Of Ipomoeassin F, Lucas Whisenhunt Aug 2018

Conformationally-Controlled Late-Stage Modifications For Sar Studies Of The C-3-Glcp Moiety Of Ipomoeassin F, Lucas Whisenhunt

Graduate Theses and Dissertations

The resin glycoside, ipomoeassin F has been shown to be extremely potent against multiple cancer lines (IC50 = 4.2-36 nM). However, the mechanism of action of this potent and complex natural product is still not fully understood. The α,β-unsaturated esters of the glucosyl moiety have been shown to be vital for the overall cytotoxicity of ipomoeassin F. Nevertheless, the importance of the tigloyl ester of the glucosyl moiety is still largely unknown. This work aimed to study the pharmacophore importance of the tigloyl ester by creating, an efficient, scalable, and flexible synthesis route for various analogs. The 18-linear step synthesis …


Preparation Of High School Chemistry Students For College Chemistry Laboratory Study, Samuel S. Jeffery Jan 1991

Preparation Of High School Chemistry Students For College Chemistry Laboratory Study, Samuel S. Jeffery

Graduate Theses and Dissertations

No abstract provided.


A Laboratory Manual And Handbook For High School Chemistry, James William Wolfe Jan 1990

A Laboratory Manual And Handbook For High School Chemistry, James William Wolfe

Graduate Theses and Dissertations

No abstract provided.


The Effect Of A Chemistry Class Careers Project On The Choice Of College And Major Of Graduates Of Springfield High School By Ellen R. Swickard, Ellen Ruth Grafton Swickard Jan 1990

The Effect Of A Chemistry Class Careers Project On The Choice Of College And Major Of Graduates Of Springfield High School By Ellen R. Swickard, Ellen Ruth Grafton Swickard

Graduate Theses and Dissertations

No abstract provided.


Proposed Workshops For The Instruction Of Mathematically Deficient High School Chemistry Students, Marie Regis Vogler Jan 1969

Proposed Workshops For The Instruction Of Mathematically Deficient High School Chemistry Students, Marie Regis Vogler

Graduate Theses and Dissertations

No abstract provided.


The Development Of The Structure And Content Of A Second Course In High School Chemistry For The Gifted Student In A School Employing A Non-Track First-Year Chemistry Program, Thomas E. Wood Jan 1968

The Development Of The Structure And Content Of A Second Course In High School Chemistry For The Gifted Student In A School Employing A Non-Track First-Year Chemistry Program, Thomas E. Wood

Graduate Theses and Dissertations

No abstract provided.


A Proposed Guide To Supplementary Materials Designated To Be Congruent With The Mental Characteristics Of The Gifted Student In An Introductory High School Chemistry Course, Carol Shaw Jan 1968

A Proposed Guide To Supplementary Materials Designated To Be Congruent With The Mental Characteristics Of The Gifted Student In An Introductory High School Chemistry Course, Carol Shaw

Graduate Theses and Dissertations

No abstract provided.


Supplementary Programmed Materials In High School Chemistry For Girls Oriented Toward A Nursing Career, Arlene Reichert Younger Jan 1968

Supplementary Programmed Materials In High School Chemistry For Girls Oriented Toward A Nursing Career, Arlene Reichert Younger

Graduate Theses and Dissertations

No abstract provided.


A Study Of The Change In Subject-Matter Content Of Ohio High School Chemistry Text-Books Used In 1957 And In 1967, Catherine Brickner Jan 1967

A Study Of The Change In Subject-Matter Content Of Ohio High School Chemistry Text-Books Used In 1957 And In 1967, Catherine Brickner

Graduate Theses and Dissertations

No abstract provided.


Suggested Improvements In The Content And Methodology Of The Traditional High School Chemistry Laboratory, Alexander Michael Samolis Jan 1967

Suggested Improvements In The Content And Methodology Of The Traditional High School Chemistry Laboratory, Alexander Michael Samolis

Graduate Theses and Dissertations

No abstract provided.


A Proposed Integrated Course In Chemistry And Physics, Mary Chaminade Abmayr Jan 1967

A Proposed Integrated Course In Chemistry And Physics, Mary Chaminade Abmayr

Graduate Theses and Dissertations

No abstract provided.