Digital Commons Network^™

Mechanisms Of Sleep And The Brain, Doungbagai Leo

Honors Theses

One of the most important homeostatic functions of the brain and body is sleep. This literary review analyzes the genes that are involved in sleep: Clock, Bmal1, Period, and Cryptochrome. It also explains the role of melatonin, GABA, orexin, and melanopsin during sleep regulation. The genes and neurotransmitters influence the suprachiasmatic nuclei and the circadian rhythm that our brain, and every cell of our bodies, have connections to. These connection help to ensure the homeostatic function of our bodies. The analysis of sleep-like states in other animals may show an evolutionary connection of sleep from non-mammals to mammals, but may …

A Comparison Of Frankenbrew And Traditionally Manufactured Brewing Equipment, Daniel King

Honors Theses

Opening a new business can be a daunting task. Between the legal paperwork, securing the best perceived location, hiring new employees, the investment can require the use of a life savings. In the brewing industry, this investment can be amplified by the cost of purchasing production scale brewing equipment. Because of this, many start-up brewing operations have turned to the use of Frankenbrew equipment within their brewing process. The term “Frankenbrew” was coined by Tom Hennessy of Colorado Boy Pub & Brewery. The term refers to any equipment incorporated into a brewery that was not originally intended for that purpose, …

Lee Honors College Mobile Application, James Ward

Honors Theses

In the spring of 2018 three Computer Science students Benjamin Campbell, James Ward, and Peter Shutt created a mobile application. This app was developed over the span of two semesters for their senior design project; a capstone to their degrees.

Their client, The Lee Honors College at Western Michigan University --referred to as LHC and WMU respectively hereafter-- has a plethora of academic and social information, and a large demand for access to it. This information includes building hours, contact information, health resources, a LHC specific course catalog, social media posts, event descriptions, and much more. The volume of information, …

Elementary/Middle School Pre-Service Teachers’ Understanding Of Variability And The Use Of Dynamical Statistical Software, Yaomingxin Lu

Research and Creative Activities Poster Day

A primary purpose of the study was to examine the effects of using dynamical statistical software (DSS) on prospective teachers’ (PSTs) understanding of statistical concepts, especially variability. Data were collected from PSTs enrolled in a probability and statistics course designed for prospective K-8 teachers. After initial analysis of the data using coding and classification schemes, we found the need to develop a more targeted framework to analyze students’ different levels of understanding. The variability framework (Garfield & Ben-Zvi, 2005) and the Structure of Observed Learning Outcomes (SOLO) taxonomy were then used in combination to develop a revised framework in order …

Assessing Land Deformation And Sea Encroachment In The Nile Delta, Egypt, Esayas Gebremichael

Research and Creative Activities Poster Day

Persistent scatterer interferometric analyses were conducted on a stack of 84 Envisat ASAR scenes spanning 7 years (2004 to 2010) over the entire Nile Delta of Egypt and surroundings to monitor the ongoing spatial and temporal land deformation, identify the factors controlling the deformation, and model the interplay between sea level rise and land subsidence to identify areas and populations threatened by sea encroachment by the end of the 21st century. Findings include: (1) general patterns of subsidence in the northern delta, near-steady (none) subsidence in the southern delta, separated by a previously mapped flexure zone undergoing uplift; (2) high …

The Proton Veto Project At Wmu/Msu, Justin Swaim

Honors Theses

The Proton Veto Wall (VW) is a charged particle detector designed and built at Western Michigan University for use at the National Superconducting Cyclotron Laboratory at Michigan State University. The VW assists the Large Area Neutron Array (LANA) with discriminating between charged particles detected via proton recoil in the scintillating material and charged particles detected from heavy ion collisions produced in the laboratory. Twenty five Eljen-200 plastic organic scintillators are arranged in a vertical position with photomultiplier tubes (PMTs) mounted to either end. The detector sits directly in front of LANA on a large stand that was assembled using T-slotted …

Similarity Based Classification Of Adhd Using Singular Value Decomposition, Taban Eslami, Fahad Saeed

Parallel Computing and Data Science Lab Technical Reports

Attention deficit hyperactivity disorder (ADHD) is one of the most common brain disorders among children. This disorder is considered as a big threat for public health and causes attention, focus and organizing difficulties for children and even adults. Since the cause of ADHD is not known yet, data mining algorithms are being used to help discover patterns which discriminate healthy from ADHD subjects. Numerous efforts are underway with the goal of developing classification tools for ADHD diagnosis based on functional and structural magnetic resonance imaging data of the brain. In this paper, we used Eros, which is a technique for …

Mapping And Interpreting The Glacial Geology Of Pictured Rocks National Lakeshore, Michigan, Sarah M. Vandermeer

Dissertations

Pictured Rocks National Lakeshore is among the most popular parks in Michigan, yet prior to this study, it was the only National Park that lacked a detailed surficial geology map characterizing the distribution of sediments and landforms. Additionally, much of the landscape remained unexplored. These factors prevented thorough interpretations of landscape development and evolution. This research aims to map and further explore the relationship of glacial sediments and landforms throughout Pictured Rocks to refine and expand the current understanding of glacial events that shaped this landscape.

A new, detailed (1:24,000-scale) surficial geology map of the ten 7.5-minute quadrangles that contain …

Interannual Variations Of Snowfall In The Lower Peninsula Of Michigan And Impacts Of Local And Remote Meteorological Conditions, Nirjala Koirala

Masters Theses

Inter-annual variation of snowfall and its relation to climate indices will help clarify and improve the prediction of total snowfall in the Lower Peninsula of Michigan (LPM). This study examines the trend and variability of annual snowfall (November- March) using 8 homogeneous weather stations in the LPM. The statistical relationship between snowfall and air temperature, Sea Surface Temperature (SST), North Atlantic Oscillation (NAO), Pacific Decadal Oscillation (PDO) and Maximum Ice Coverage(MIC) of Lake Michigan is calculated. The long-term trend in the snowfall data set from 1950 to 2015 is removed before any statistical correlation analysis is conducted. My analysis suggests …

Statistical Models For Correlated Data, Xiaomeng Niu

Dissertations

Correlated data arise frequently in many studies where multiple response variables or repeatedly measured responses within subjects are correlated. My dissertation topic lies broadly in developing various statistical methodologies for correlated types of data such as longitudinal data, clustered data, and multivariate data.

Multiple response variables might be relevant within subjects. A univariate procedure fitting each response separately does not take into account the correlation among responses. To improve estimation efficiency for the regression parameter, this study proposes two estimation procedures by accommodating correlations among the response variables. The proposed procedures do not require knowledge of the true correlation structure …

Using Agent-Based Implementation Of Active Data Bundles For Protecting Privacy In Healthcare Information Systems, Raed M. Salih

Dissertations

Sharing healthcare information—including electronic health/medical records (EHRs/EMRs)—among healthcare information systems is necessary for improving the quality of healthcare. However, facilitating data exchange increases privacy threats—due to easier copying and dissemination of healthcare information.

We propose a solution that provides privacy protection for patients’ EHRs/EMRs disseminated among different authorized healthcare information systems. Our solution builds upon the existing construct named an Active Data Bundle (ADB). In the proposed solution, ADBs keep EHRs/EMRs as sensitive data; include metadata describing sensitive data and prescribing their use; and encompass a policy enforcement engine (called a virtual machine or VM), which …

Edge Induced Weightings Of Uniform Hypergraphs And Related Problems, Laars C. Helenius

Dissertations

The starting point of the research is the so called 1-2-3 Conjecture formulated in 2004 by Karoński, Luczak, and Thomason. Roughly speaking it says that the edges of any graph can be weighted from {1, 2, 3} so that the induced vertex coloring (as the sum of weights adjacent to a given vertex) is proper. The conjecture has attracted a lot of interest from researchers over the last decade but is still unanswered. More recently, the conjecture has been studied for hypergraphs.

The main result of this dissertation shows in particular that an analogous conjecture holds for almost all uniform …

Statistical Properties Of Population Stability Index, Bilal Yurdakul

Dissertations

Population stability is an important concept in model management. It is crucial to monitor whether the current population has changed from the population used during development of a model. For example, has the distribution of credit scores changed, and is the existing credit score model still valid? Population change may occur for many reasons–change in the economic environment, strategic change in the business, policy changes within the company, or changes in regulatory environment.

The population stability index (PSI) is a statistic that measures how much a variable has shifted over time, and is used to monitor applicability of a statistical …

Mapping Bedrock Topography Of The Portage And Schoolcraft Nw 7.5’ Quadrangles, Kalamazoo Co. Mi, Using The Hvsr Passive Seismic Method, Benjamin B. Seiderman

Masters Theses

This study utilizes the Horizontal to Vertical Spectral Ratio (HVSR) technique to map bedrock topography in the Portage and Schoolcraft NW quadrangles, Kalamazoo Co., MI, looking for buried bedrock valleys. Glacial sediment-landform assemblages dominate the study area, due to multiple advances of the Laurentide Ice Sheet (LIS). Tunnel valleys, which are one type of buried valley, are eroded by subglacial meltwater and commonly filled with the coarser varieties of glacial outwash, making them potential aquifers. The HVSR technique measures the ratio of horizontal to vertical ground motion, excited by ambient seismic noise, resulting in a peak at the resonance frequency. …

A Survey Of Security And Privacy In Mobile Cloud Computing, Bhuvaneswari Rayapuri

Masters Theses

Cloud Computing is an emerging technology that provides shared processing resources and data to computers and other devices on demand. On the other hand, Mobile Computing allows transmission of data, voice and video. From these two there emerges a new concept Mobile Cloud Computing which not only overcomes the problems of Mobile Computing but also integrates Cloud Computing into Mobile Environments to overcome obstacles related to Performance, Security and Environment. This paper also provides a decent description on Security and Privacy, its related problems, threats and challenges. This paper first provides details on survey of Mobile Cloud Computing, then it …

Organocatalyzed Synthesis Of Epoxides From Chalcones Utilizing Amino Acids, Sabrina N. Kegeler

Masters Theses

The epoxide functional group is important throughout the chemical and pharmaceutical industries, as well as in nature. In the chemical industry, epoxides are present in resins and fragrances. In the pharmaceutical industry, epoxide-containing compounds are used as intermediates in the manufacturing of drugs. In nature, many natural products contain epoxide groups and are used for medicinal purposes, and for models to create synthetic molecules.

One approach to epoxide synthesis involves the use of an alkene precursor, a base, and an oxidizing agent. This is where my investigations began. The first step was to optimize the epoxidation reaction, examining substrate scope, …

Geochemical And Petrological Investigation Of The Prospective Ni-Cu-Pge Mineralization At The Echo Lake Intrusion In The Upper Peninsula Of Michigan, Usa, Alexander J. Koerber

Masters Theses

The Echo Lake Intrusion is located in Houghton and Ontonagon counties in the Upper Peninsula (UP) of Michigan. The intrusion is approximately 200 m below the surface and covers approximately 18 km2 in lateral extent. It is associated with the magmatic activities of a 1.1 Ga geologic event called the Midcontinent Rift. The rift is responsible for the formation of Ni-Cu ± PGE deposits in the Lake Superior Region. Based on its association with the Midcontinent Rift and a Cu and PGE enriched layer, the Echo Lake intrusion is identified as a prospect for an economic magmatic sulfide deposit.

The …

Determinants Of Household Water Use In The City Of Kalamazoo, Michigan: The Role Of Climate And Socioeconomic Factors, Danielle Molenaar

Masters Theses

Located in the Great Lakes Watershed, the City of Kalamazoo can be considered “water rich”. Therefore, the area has been absent from water use studies. Water use studies are beneficial in all locations; as they can aid city planners, water resource managers, and utility companies. This study examines how household monthly water use in the City of Kalamazoo is impacted by both climate and socioeconomic variables over the period 2006-2016. Household level data were aggregated into census tracts to obtain monthly tract averages for the eleven-year period. Ordinary least squares regression (OLS) was used to determine which variables impact the …

Geologic Mapping Of The Bronson North And Bronson South 7.5-Minute Quadrangles, Branch County, Michigan, Karl John Backhaus

Masters Theses

This study contributes to a better understanding of the glacial history of southwest Michigan through detailed surficial geologic and bedrock topography mapping within the Bronson North and Bronson South Quadrangles in Branch County, Michigan. This project was supported during the summer of 2017 by the USGS EDMAP program in conjunction with the Michigan Geological Survey. Hand-auger borings, grain size analysis tests, passive seismic depth-to-bedrock measurements, and ground penetrating radar transects were collected for this study. There are 350 feet of bedrock relief from west to east across the quadrangles, including a bedrock cuesta of Mississippian Coldwater Shale. This cuesta underlies …

A Holistic Computational Approach To Boosting The Performance Of Protein Search Engines, Majdi Ahmad Mosa Maabreh

Dissertations

Despite availability of several proteins search engines, due to the increasing amounts of MS/MS data and database sizes, more efficient data analysis and reduction methods are important. Improving accuracy and performance of protein identification is a main goal in the community of proteomic research. In this research, a holistic solution for improvement in search performance is developed.

Most current search engines apply the SEQUEST style of searching protein databases to define MS/MS spectra. SEQUEST involves three main phases: (i) Indexing the protein databases, (ii) Matching and Ranking the MS/MS spectra and (iii) Filtering the matches and reporting the final proteins. …

Support Assurance-Based Software Development For Mission Critical Domains Using The Model Driven Architecture, Chung-Ling Lin

Dissertations

In the past decades, software development for mission critical applications has drawn great attention not only in various mission critical communities but also software engineering communities. One of the important reasons is that the failure of these systems can lead to some serious consequences such as huge financial loss and even loss of life. Therefore, software certification has become an important activity for mission critical applications in that software assurance for such a system should be certified. With the increasing complexity of a software system in mission critical sectors, certifiers have found hard time to understand how a software system …

Denoising Large Neuroimage Mri Data Using Spatial Random Effect Models, Leonard Chukuma Johnson

Dissertations

Spatial smoothing in Magnetic Resonance image (MRI) involves applying a filter to remove high frequency information and consequently improves signal-to-noise ratio that can greatly aid neurosurgeons in pre-surgical planning stages of tumor resection. This immensely reduces the time spent on Electrical stimulation mapping (ESM) prior to surgery. MRI's three-dimensional data provides voxel intensities with complex spatial relationship. The standard de facto spatial smoothing method, Gaussian Kernel smoothing, is satisfactory since a uniform smoothing is done for the whole brain. Secondly, the kernel smoothing technique assumes normality for the voxel intensity, but there is ample evidence in current research that indicates …

Exploring The Use Of Hierarchal Statistical Analysis And Deep Neural Networks To Detect And Mitigate Covert Timing Channels, Omar Darwish

Dissertations

Covert timing channels provide a mechanism to transmit unauthorized information across different processes. It utilizes the inter-arrival times between the transmitted packets to hide the communicated data. It can be exploited in a variety of malevolent scenarios such as leaking military secrets, trade secrets, and other forms of Intellectual Property (IP). They can be also used as a vehicle to attack existing computing systems to disseminate software viruses or worms while bypassing firewalls, intrusion detection and protection systems, and application filters. Therefore, the detection and mitigation of covert channels is a key issue in modern Information Technology (IT) infrastructure. Many …

Elucidation Of The Toxicity Of Anthropogenic Nanoparticles In Environments Containing Heavy Metals, Chartanay Bonner

Dissertations

The design, synthesis, and applications of anthropogenic nanoparticles continue to rise as technologies utilizing the unique chemical and physical properties of materials with nanoscale dimensions emerge. Engineered silver nanoparticles (Ag NPs) possess antimicrobial properties toward several strains of antibiotic-resistant bacteria. The manufacturing and use of Ag NPs have led to their increased presence in the environment as pollutants. The interaction of Ag NPs with other pollutants influence their surface properties, aggregation state, stability and consequently, their toxic response toward microbial pathogens. In the present study, we examined the interaction of heavy metal ions (Cd²⁺, Hg²⁺, and …