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A 3d Simulation Of Leukocyte Adhesion In Blood Flow, Tai-Hsien Wu

Dissertations

It has been widely acknowledged that further understanding about the dynamics between blood cells and blood flow can help us gain more knowledge about the causes of diseases and discover more effective treatments. Examples of such dynamics include red blood cell (RBC, or erythrocyte) aggregation, white blood cell (WBC, or leukocyte) margination, and WBC extravasation. WBC extravasation is an important multiple-step process in the inflammatory response and therefore has drawn considerable attention over the past two decades. In this multiple-step process, a WBC undergoes at least four steps, including capture, rolling, firm adhesion, and transmigration, and each step is influenced …

Design Of Force Versus Displacement Test Stand, Andrew Fritchley

Honors Theses

Performing mechanical design around sensors is a critical skill which all engineering students should be familiar with. Of equal importance is gathering and correctly interpreting electrical data from engineering tests. The aim of this project is to design a force versus displacement test stand for applications related to the measurement of spring force-displacement correlation. The design uses a strain gauge load cell, and a magnetic linear encoder to provide accurate, repeatable force and travel measurements. A mechanical design to mount each sensor was created based initial project constraints. Finite element analysis was performed on all critical components to ensure that …

Music Keyboard Based On Flexible Hybrid Electronics, Anthony Hanson

Honors Theses

With the idea of creating a product using flexible hybrid electronics, the group decided to create a musical keyboard like a synthesizer. This is implemented using a printing technique called screen printing. This allowed the group to make several copies of the same sensors with a consistent thickness, roughness, and size. These keys, made of silver, are used as capacitive proximity sensors. When another conductive material comes within range of the key to change the polled capacitance by 2.7 pF, the note corresponding with that key is outputted.

In the interest of making this project a useful tool for someone …

Land, Air, Sea, Rover (Lasr) - Unmanned Vehicle, Gabriel Prescinotti Vivan

Honors Theses

This senior design project encompassed the optimization of a previously built quadcopter, as well as the design of new components for additional functions and increased range of operations. The previous vehicle was designed to operate as a helicopter, land rover, and submarine. Although the vehicle operates successfully in these three environments, it is not very successful on transitioning between them, i.e. cannot take off from underneath water. This year’s project goals included optimizing the current vehicle so that it could transition seamlessly between its functions and adding an additional function: to be able to rover at the bottom of a …

Structural Reinforcement Of Streamline Tubing, Peter Grohs

Honors Theses

Structural integrity of suspension components is important to the safety and the longevity of vehicles. Streamline tubing, an aerodynamically shaped material used in high performance vehicle controls, can be prone to failure if not properly analyzed for its asymmetric geometry. The component was redesigned as a composite structure using modern materials to make a highly aerodynamic product stiffer, stronger, and lighter per unit weight than a conventional all steel design. Finite element analysis was conducted and five prototypes using different materials were constructed and tested. This method of maximizing component lightness and stiffness using the beneficial properties of each material …

Distillation Optimization In The Pharmaceutical Industry, Clayton Carter

Honors Theses

Distillations are commonly used throughout industry to perform separations by phase change. producing a liquid phase and vapor distillate. However. the process of distilling can be slow and energy intensive, providing a limitation in the production process. Possible improvements to current distillation systems were considered on the basis of thermal efficiency, material throughput (cycle time), and material tolerance. Consideration was given to ensure maintenance is straightforward and relatively quick, as fouling, contamination and tank utilization were concerns. Economic viability of the improvements was completed to determine the project benefit. The optimized design offers increased efficiency for production lines.

Optimizing Frosted Mini-Wheats' Finished Food Cooling Process, Jessica Graves

Honors Theses

Analyzing energy intensive processes in industry is crucial for improving sustainability, lowering costs, and increasing profit margins on products. Material and energy balances were performed to identify process losses in the cooling of Frosted Mini-Wheats. Existing cooling technology was compared to alternate technology available on the market, and a cost analysis was performed to compare all options explored. Recommendations were made to the system to potentially reduce the line's energy usage and downtime, with the objective of creating a more sustainable and efficient process.

Electromagnetic Radiation Shield For Spacecraft, Oseas Hudy-Velasco

Honors Theses

To protect astronauts from high-energy radiation during long-duration missions, an electromagnetic radiation shield was designed and sized for the Orion spacecraft with physical dimensions at a 1:100 scale and magnetic fields and particle energies at a ∼1:10833.3 scale. The electromagnetic radiation shield was simulated in the multi-physics software Comsol using the Magnetic Fields and Particle Tracing modules. The scale model used a DC amperage of 60 A with a 9-turn solenoid wound in three layers and the full-size system used a DC amperage of 6500 A and a 5-layer solenoid of 390 turns per layer. These models generated magnetic fields …

An Investigation Of The Efficacy Of Corn Cob Hemicellulose As A Gas Barrier And Dry Strength Agent On Previously Uncoated Linerboard, Zachary Witherspoon

Honors Theses

Two types of xylan, water soluble and insoluble, were extracted from corn cobs and made into liquid coatings and applied to uncoated linerboard with a fine, #8 Meyer rod, with the intention of creating a gas barrier and increasing strength properties. The xylan coatings were plasticized with sorbitol and crosslinked with citric acid, and the crosslinking reaction catalyzed with sodium hypophosphite. A 1% konjac glucomannan comparison coating was created (with the same plasticizer and crosslinker) to serve as an alternative coating based on previous research in the department, but it failed as a paper coating due to the presence of …

Optimization Of Toaster Pastry Icing Preparation And Application, Rebecca Martus

Honors Theses

The Kellogg Company is interested in optimizing the way the icing for a baked good is prepared and applied during production. The current method has not been significantly changed since the item was first introduced over 50 years ago. A new process was developed to make a more efficient preparation and application of the icing operation. New equipment was identified based on established methods in the food industry. The new equipment and process was verified after the mass and energy balances were calculated. A capital and operating cost analysis was performed to determine if the introduction of the new process …

Compressed Air Systems Evaluation And Improvement, Lukas Swoboda

Honors Theses

This project was centered on recommending a new air compressor system for the Fluid System Connectors division of Parker Hannifin in Otsego, Michigan. The recommended compressor for the plant is a 250hp variable speed drive Ingersoll Rand Compressor. It is recommended that this compressor, along with two 35hp compressors already purchased by Parker be tied together using an automated system. In addition to the compressor, a flow controller was recommended to be implemented into the system.

Given that leaks are also a problem in the system, it is recommended that the majority of air leaks in the system be fixed …

Natural Polymer Barrier Coatings For Oil And Grease Resistance, Andrew Kathan

Honors Theses

Many barrier coating formulations currently used for oil and grease resistance development in the paper industry have issues with sustainability, biodegradation, or have health concerns associated with them. This thesis tests two starches as barrier coatings to develop oil and grease resistance for food grade packaging sheets. Starch is compatible with almost all papermaking chemicals, is biodegradable, and is easily treated in wastewater systems making it a great candidate to create a more sustainable barrier coating. Cooked hydrophobic starch esters have a unique shear-thinning rheology that allow for high solid starch coatings to be applied with a reduced risk of …

Design Of An Electric Propulsion Thruster Breakout Box System, Ryan Powers

Honors Theses

When performing experiments in the Aerospace Laboratory for Plasma Experiments (ALPE), creating test setups and working with electrical equipment can become dangerous and tedious. A breakout box was required that ensures the ability to troubleshoot electrical problems, decrease the time needed to reconfigure equipment for an experiment, and decrease the potential for a safety hazard. The goal was to design a box that would house most of the equipment necessary to easily obtain current and voltage data from experiments in a safe, reliable manner. Three primary electrical components used in the circuit of the box were the current sensor, the …

Distillation Optimization In The Pharmaceutical Industry, Daniel Vanzweden

Honors Theses

Distillations are commonly used throughout industry to perform separations by phase change, producing a liquid phase and vapor distillate. However, the process of distilling can be slow and energy intensive, providing a limitation in the production process. Possible improvements to current distillation systems were considered on the basis of thermal efficiency, material throughput (cycle time), and material tolerance. Consideration was given to ensure maintenance is straightforward and relatively quick, as fouling, contamination and tank utilization were concerns. Economic viability of the improvements was completed to determine the project benefit. The optimized design offers increased efficiency for production lines.

Solid State Light Conversion, Jumana Turkistani

Honors Theses

Demand for innovative and energy-efficient technology has increased as an environmentally sustainable society has become priority. Technological development of solid-state light plays a part in meeting that demand. Our research has revealed that LED (Light Emitting Diode) lighting uses less energy and is a more cost effective and environmentally responsible choice than incandescent and fluorescent lighting. Converting from incandescent and fluorescent dominated lighting to LED lighting may be cumbersome but can result in a classroom milieu that is attractive, cost/energy effective, easy to manipulate as well as facilitative to learning. For this project, a small-scale mockup of the light fixtures …

From Architectural Design To Structural Analysis: A Data-Driven Approach To Study Building Information Modeling (Bim) Interoperability, Mohammed Aldegeily

Masters Theses

BIM has been playing an essential role in building construction projects in recent years. It was used to automate many tasks such as clash detection, 4D planning, and quantity takeoff, among others. However, the interoperability of BIM still lacks in many fields across the architecture, engineering, and construction domains. This research studies the interoperability between architectural design and structural analysis. The goal is to explore structural analysis of BIM models through data transfer processes between different software platforms via three types of paths: (1) Application Programming Interface (API); (2) “immediately connect,” which is the direct link between software programs from …

Forward-Looking, Velocity-Driven, Powertrain Modeling And Optimal Control For Continuous Variable Transmission, Paresh Deshmukh

Masters Theses

This thesis is the second part of a two-part study focused on improving Continuous Variable Transmission (CVT) ratio management and control. The objective of the overall project was to develop a methodology for a vehicle with a CVT and a downsized gasoline engine to deliver the maximum vehicle fuel economy within drivability and performance constraints. The first part of this study, as described in [1], focuses on developing a cycle driven model for optimizing the CVT ratio. The study presented in this paper focuses on developing a velocity driven model to simulate the real-time behavior of a vehicle. The results …

Power-Efficient And Highly Scalable Parallel Graph Sampling Using Fpgas, Muhammad Usman Tariq

Masters Theses

Energy efficiency is a crucial problem in data centers where big data is generally represented by directed or undirected graphs. Analysis of this big data graph is challenging due to volume and velocity of the data as well as irregular memory access patterns. Graph sampling is one of the most effective ways to reduce the size of graph while maintaining crucial characteristics. This thesis presents design and implementation of a field programmable gate array (FPGA) based graph sampling method which is both time- and energy-efficient. This is in contrast to existing parallel approaches which include memory-distributed clusters, multicore and GPUs. …

Determination Of Chemical Notch, KChem On Aluminum And Steel When Subjected Under Slow Strain Rate Test In Corrosive Environment, Joshua Teo Lee Kuok

Masters Theses

When designing for any mechanical components or system, the question would arise as to how the material would react to the loads subjected on it? Would the component survive its service load? How would it react to environmental corrosion? To answer these questions, the technique used in this thesis paper is the Slow Strain Rate Test (SSRT) method. Aluminum and steel were chosen as the material to be tested in this paper. Al 7075-T651, and Al 6061-T651 was chosen due to its wide range of application, high strength to weight ratio and ease of machinability. It is highly used in …

Investigation Of Discrete Element Methods For Stud To Turf Interactions, Justin Rittenhouse

Masters Theses

Artificial turf is frequently used in sports today and attempts to advantageously replicate a natural grass/soil playing surface. Despite numerous advantages, the technology is correlated with an increase in injuries. The concept behind this research is to create and validate a discrete element model (DEM) for the ground/foot interaction through the use of open source software. After validation, the goal is to analyze an arrangement of studs to determine what role stud geometry plays on torque [N-mm] and force [N] generation. The validation data was provided through laboratory experiments. Three football studs attached to a rigid bracket were turned at …