Digital Commons Network^™

Department Chairs’ Impact On The Diversity, Equity, And Inclusion Of Their Departments, Nicholas R. Garcia Ii

Theses and Dissertations

Department chairs serve not only as the leaders of their departments but also as middle managers in their schools, colleges, and universities. While many department chairs see their role as having little authority, they still play an integral role in day-to-day campus operations (Hunt & Jones, 2015). As leaders of their departments, chairs can directly influence the department’s organizational culture (Schein, 2010), including the culture of diversity and inclusiveness. Departments nationwide are being held responsible for increasing the diversity of the faculty and responding to students' calls for diversity. Departmental organizational culture and the role of the chairperson are essential …

Modeling And Mitigating Power Grid Vulnerabilities: A Comprehensive Analysis Of Renewable Energy Integration, Cascading Failures, And Microgrid Resilience, Saikat Das

Theses and Dissertations

In modern power systems, rapid integration of renewable energy and the emergence of microgrid technology emphasize the necessity for a comprehensive understanding of vulnerabilities and robust defense mechanisms. The research begins with an exploration of power grid vulnerabilities to cascading failure amidst the increasing integration of renewable energy sources. A novel power balance technique is employed for cascading failure analysis and power grid vulnerability measurement. Simulation results indicate that the growing penetration of renewable energy has a proportionally higher impact on grid vulnerability to cascading failures. After a certain level of renewable energy penetration, some systems may deteriorate rapidly, necessitating …

Mathematical Modeling And Analysis Of Inflammation And Tissue Repair: Lung Inflammation And Wound Healing In Corals Under Stress, Quintessa Hay

Theses and Dissertations

A variety of insults, including tissue injury and/or exposure to pathogen, elicit an immune response in many organisms. An improperly regulated immune response can result in deleterious effects to the organism. Here we present models for lung injury in young and old mice and models for wound healing in coral reefs.

It is well known that the immune response becomes less effective in older individuals. This is of particular interest in pulmonary insults such as ventilator induced lung injury (VILI) or lung infection. We extended a mathematical model for the inflammatory response to VILI and used experimental data to select …

Measuring The Properties Of Rod-Shaped Bacteria By Single-Entity Electrochemistry, Ashley Tubbs

Theses and Dissertations

Antibiotic-resistant bacteria pose a significant and escalating threat to hospitals around the world, necessitating the development of rapid and sensitive detection methods. Single-entity electrochemistry has emerged as a promising approach for detecting and identifying such bacteria, and monitoring the efficacy of antibiotics in real-time. Herein, we employ the translational diffusion equation for circular cylinders to predict the collision frequency of rod-shaped bacteria, informing our experimental setup. Our work demonstrates that lab-fabricated Pt ultramicroelectrodes can sensitively detect bacteria at femtomolar concentrations under migration-controlled conditions. Further, we present a method implemented in MatLab to automate the analysis of step-like signals observed in …

Effects Of Mindfulness Training On Prosocial Responses In Intergroup Relations: A Pilot Randomized Controlled Trial, Denise Yiran Zheng

Theses and Dissertations

Based on social identity theory and intergroup emotions theory, individuals feel for and act toward others based on their group-based social identities. Recent research shows that mindfulness can enhance prosocial responses toward others across group divides. The current research examined the effects of mindfulness training on prosocial behavior in intergroup relations where such behavior is difficult (e.g., with marginalized or devalued social groups). The study also examined potential mechanisms, namely state empathic concern and appraisal, that may explain how mindfulness increases prosocial behavior toward outgroups. This study compared the effects of a 2-week mindfulness training to a matched coping training …

Exploring The Experiences Of Faculty Learning To Teach Online: A Case Study, Peyton P. Burgess Jr

Theses and Dissertations

Through an examination of literature, interviews and focus groups with participants of a faculty development program on online teaching and learning at a large Public Mid-Atlantic Urban University (PMUU), this research aimed to uncover the elements of a faculty development course or other impacts that contributed to the success or hindrance of faculty in their online course delivery. This qualitative study aimed to foster collaborative relationships with participants and resulted in data that might inform the development of faculty and their online courses in similarly situated contexts.

Politics Of Being A Lover: In Art, (Space) And Kink, Rabeeha Adnan

Theses and Dissertations

Politics of being a lover: in art, (space) and kink explores my relationship with my practice through observations and stories that draw parallels with romance and kink. Narrated as love affairs turned into complex commitment, it shuffles through logics of structural power, control, and communication in the context of praxis and art institutions.

In Shame I Will Find Paradise, Taehee Whang

Theses and Dissertations

As a Korean American non-binary digital artist and designer, my recent explorations have focused on using voice as a medium to articulate nuanced feelings of displacement and the intricate relationships between language, identity, and expression. This journey expands beyond my personal experiences with gender dysphoria, delving into the lives of non-binary and transgender individuals undergoing gender-affirming voice therapy. Through my thesis research, I have developed interactive multimedia installations inspired by dialogues with individuals such as Umico Niwa, who traveled to Korea for voice feminization surgery, and Jeong Yoon Lee from Hyperlink Press, a four-year participant in Hormone Replacement Therapy (HRT). …

Graph Coloring Reconfiguration, Reem Mahmoud

Theses and Dissertations

Reconfiguration is the concept of moving between different solutions to a problem by transforming one solution into another using some prescribed transformation rule (move). Given two solutions s₁ and s₂ of a problem, reconfiguration asks whether there exists a sequence of moves which transforms s₁ into s₂. Reconfiguration is an area of research with many contributions towards various fields such as mathematics and computer science.
The k-coloring reconfiguration problem asks whether there exists a sequence of moves which transforms one k-coloring of a graph G into another. A move in this case is a type …

Humans Are Dust, Chelsea Nanfelt Rowe

Theses and Dissertations

I probe how objects act as intermediaries between people. These explorations reflect on the delicate navigation that happens when we intertwine our lives with others. My curiosities lie in the fuzzy aura of human life that encircles materials. Do our materials possess life or do we imbue and inject the materials in our world with personalities reflective of ourselves? My motivation for this project is to highlight the stories infused in and witnessed by things we surround ourselves with and use daily.

The Incoherence Of Orientalists, Sarah Zaid Alafifi

Theses and Dissertations

Orientalism, the Western practice of fetishizing cultures, extends beyond mere misrepresentation of the “other;” it epitomizes the underlying structures of colonialism and imperialism, infiltrating everyday life and eroding the moral fabric of Islamic society.

This thesis analyzes colonial control through the exercise of political power and the production of knowledge, investigating key events related to Napoleon’s Egyptian campaign and the narratives of resistance that emerged in opposition to it.

Through the lens of this 18th-century expedition, the study examines how Western knowledge systematically contributed to the dismantling of Islamic systems of knowledge. Select phrases from Colonial-era printed proclamations are extracted …

The Role Of Notch1 Signaling In Regulating Neurogenesis In The Olfactory Bulb Following Traumatic Brain Injury, Sarah A. Baig

Theses and Dissertations

In the United States, more than 20.5 million adults over the age of 40 suffer from olfactory dysfunction, with TBI attributing to 5-17% of all olfactory dysfunction cases. Although often initially undetected and less conspicuous than other cognitive and behavioral impairments, olfactory dysfunction may have a significant negative impact on patients' quality of life and ability to accomplish activities of daily living, therefore the pathophysiology of these disorders should be understood. The production of neural stem cells enhances the repair and regeneration of the injured brain following a TBI. One of the primary endogenous neural stem cell generation sites in …

Acute Effects Of An Oral Nicotine Pouch In People Who Use Smokeless Tobacco, Alisha Eversole

Theses and Dissertations

People who use smokeless tobacco (SLT) are exposed to a variety of carcinogenic toxicants, yet, despite health risks, nearly 6 million people in the US use SLT. SLT contains and delivers nicotine, a psychostimulant that causes dependence and hinders cessation efforts. An orally-administered nicotine pouch marketed as “tobacco-free” recently has become available for purchase in the US. However, there are very few non-industry-sponsored studies regarding the effects of these oral nicotine pouches.

The current study used clinical laboratory methods to determine the acute effects of an oral nicotine pouch in people who use SLT. Participants completed four sessions (within subjects, …

"I Call Them Supermoms": Therapists' Reflections On The Impact Of Youth Sexual Offending On Latina Mothers, Mauricio P. Yabar

Theses and Dissertations

Families of youth who have sexually offended often suffer significant collateral consequences following the discovery of the sexual offense. Samples in research with these families disproportionately consist of mothers and other female parental figures. This is rarely acknowledged in the literature, and the experiences of these mothers have not been explicitly examined. In addition, research on the experiences of these families has largely ignored factors related to race and ethnicity. This is a significant oversight considering the prevalence of systemic racism and discrimination in the United States, particularly in the systems with which these families must interact (e.g., juvenile justice …

Zaytouna: Rooted Histories In Uprooted Memories, Naima M. Almajdobah

Theses and Dissertations

Palestinians, whether living under occupation or—like myself—in the diaspora, experience a complex journey of displacement and dispossession stemming from the Nakba of 1948. This reality shapes our collective identity, rooted in our connection to our homeland.

Zaytouna explores an under-researched topic: the relationship between the olive tree and uprooted Palestinians. It reveals a rich tapestry of narratives that encompass the quintessential and everlasting relationship between a land and its people. The resulting interactive archival installation consists of two parts: audio recordings from Palestinians in the diaspora, which capture their memories and voices; and visuals, which represent the storytellers’ places of …

Notes Toward A Personal Afrofuturism, Jalen T. Adams

Theses and Dissertations

This paper is penned by a young adult who is generally confused about a lot of things regarding life, but has one singular focus that is perhaps larger than life—trying to find the bridge between a future already lived, and a past yet to happen. These are his findings so far.

Latent Profiles Of Child Coping And Perception Of Experience Processes To Predict Long-Term Symptoms Of Depression, Intrusive Grief, And Suicidality Outcomes In Parentally Bereaved Children, Rebecca Hoppe

Theses and Dissertations

Childhood bereavement is a significant public health issue and the most distressing form of childhood trauma. The death of a parent can disrupt the course of a children's development and potentially predispose them to enduring adverse mental health outcomes, such as depression, intrusive grief, and suicidality. Recognizing grief as a dynamic process, theories have suggested that children’s unique coping and perceptions of experience can contribute to variations in individual adaptations to the death and the onset of mental health problems. The goals of this study were to (a) use latent profile analysis to empirically group recently bereaved children into distinct …

Exploring Emerging Adults' Consideration Of Future Cancer Risk Reduction: Opportunity For Shifting Prevention Paradigms?, Jacqueline Knight Wilt

Theses and Dissertations

Background
Early onset colorectal cancer (EOCRC) among individuals younger than age-based population prevention screening guidelines has been linked to lifestyle-related risk factors. Emerging adulthood (18-25 years) is when elevated autonomy can alter health behaviors with implications for future health. Greater consideration of future consequences for behavior predicts several lifestyle health behaviors. Future consideration is sensitive to resource availability, and thus may differ between students who are first-generation and/or from low-income households (FGLI) compared to Non-FGLI. This dissertation study aimed to (1) characterize college students’ consideration of future cancer risk (CFC-Cancer), perceived colorectal cancer (CRC) risk and associations with EOCRC risk …

Investigating The Impact Of Chronic Inflammatory Pain On Ethanol Consumption In Mouse Models., Joshua L. Hunt

Theses and Dissertations

Chronic pain affects nearly 20% of Americans annually and for many alcohol provides a convenient and legally acquired palliative. Population-based studies have suggested a link between increased alcohol use and reduced pain, but chronic or excessive alcohol use potentiates the risk to develop alcohol dependence and neuropathy. However, sex differences in chronic pain and alcohol abuse are still not well understood. In the present study, we investigated whether chronic inflammatory pain using the inflammatory agent Complete Freund’s Adjuvant (CFA) model could alter ethanol consumption in male and female C57BL/6J mice. We observed that only CFA-treated male mice increased their ethanol …

On The Rebound: Resilience And Subjective Cognitive Symptoms In Cancer, Giuliana V. Zarrella

Theses and Dissertations

Recent studies have shown a strong connection between resilience and subjective cognitive symptoms in clinical populations. However, there is limited understanding of this relationship in cancer survivors, and no studies examine whether resilience training could alleviate subjective cognitive symptoms in these patients. This study examined the relationship between subjective cognitive function and resilience in non-CNS cancer survivors who participated in a resiliency training intervention, at baseline and from pre- to post-intervention, as well as investigated potential influences of change in subjective cognition. Adult cancer survivors (N=275) participated in the Stress Management and Resilience Training-Relaxation Response Resilience Program (SMART-3RP) …

Doctors And Saints: Preparing Albert Camus’S The Plague To Address The Dangers Of Christian Nationalism, Christopher J. Williams

Theses and Dissertations

My project is focused on identifying and responding to Christian nationalism in United States politics by utilizing Albert Camus’s novel The Plague. The Plague found heightened popularity during the COVID-19 pandemic and its lasting legacy points to what should be long-term prominence in the public eye. With its popularity and anti-fascist content, The Plague is an appropriate text to utilize for addressing America’s Christian nationalism. My paper functions with a foundation on the work of Kenneth Burke, particularly his focus on literature’s utility as equipment for living.

I use my project to suggest that The Plague is not in an …

Identifying Mechanistic Pathways To Rigidity Associated With Obsessive-Compulsive Personality Disorder Traits Using A Novel Decision-Making Paradigm, Hannah L. Heintz

Theses and Dissertations

Cognitive and behavioral rigidity is observed across several mental disorders and is a defining characteristic of Obsessive-Compulsive Personality Disorder (OCPD), a highly prevalent and debilitating, yet understudied, disorder. In particular, treatments for OCPD are underdeveloped due to our poor understanding of the mechanisms leading to the disorder’s key feature of rigidity. Two related disorders, anorexia nervosa (AN) and obsessive-compulsive disorder (OCD), have shown distinct mechanistic pathways leading to symptoms of rigidity, indicating that this trait can arise as a result of a number of differentially impaired cognitive processes, each requiring unique interventions. To examine the relationship between symptoms of OCPD …

Extrusion-Based Additive Manufacturing Of Magnetic Heat Exchange Structures For Caloric Applications, Vaibhav Sharma

Theses and Dissertations

Currently, the commercial building sector accounts for 18% of total U.S. end-use energy consumption, of which almost a third was from on-site combustion of fossil fuels for space and water heating. Magnetic heat pumping (MHP) technology is an energy-efficient, sustainable, environmentally-friendly alternative to conventional vapor-compression cooling technology. Several MHP designs today are predicted to be highly energy efficient, on condition that suitable working materials can be developed. This materials challenge has proven to be daunting due to issues associated with intricate synthesis/post-processing protocols and complications related to shaping the mostly brittle magnetocaloric alloys into thin-walled channeled regenerator structures to facilitate …

A Critical Perspective On Supporting Parents In Facilitating Informal Steam Learning On Children's Early Literacy Development, Suzanne G. Alexandre

Theses and Dissertations

Considering that parents/caregivers and home environment play an influential role in a child’s school readiness and future academic success, this study sought to support parents in using facilitation strategies to engage their child in informal learning at home. In order to examine if access to support for parents of preschoolers influenced parents’ confidence in their ability to facilitate informal learning at home, the project used informal STEAM learning, for context. The study also examines the potential impact of informal STEAM learning on children's school readiness and early literacy skills and the intersections of parent involvement, STEAM, and school readiness through …

Exploring Drivers Of Sex-Based Disparities In Relapsing Multiple Sclerosis, Stephanie K. Buxhoeveden

Theses and Dissertations

Females are three times more susceptible to relapsing multiple sclerosis (MS) and males typically have more severe disease, but the molecular underpinnings of these sex-based disease disparities are unknown and represent a critical knowledge gap.Subject Population: Blood samples from a demographically homogenous group of treatment naïve males and females with relapsing-MS and healthy controls. Research Design: Cross-sectional combinatorial omics pilot study. Instruments: Whole transcriptomic analysis with messenger RNA (mRNA) expression profiling using next generation sequencing (RNA-seq) and micro-RNA (miRNA) expression using NanoString technology. Aim 1) Identify and compare the actively expressed mRNAs in the transcriptome of males and …

Biodistribution Comparison Of Fentanyl And Morphine Following Acute And Repeated Expsoure, Rosamond M. Goodson

Theses and Dissertations

The ongoing opioid crisis constitutes a dire public health threat that has resulted in staggering loss of life. In 2021, opioids were implicated in over 75% of the approximately 107,000 deaths attributed to drug overdose (CDC), and synthetic opioids such as fentanyl and its analogues are key drivers of the surge in opioid fatalities in recent years. Although fentanyl is a μ opioid receptor agonist, it has several distinct attributes compared to other drugs in this category, such as morphine. These include enhanced lipophilicity, heightened potency to induce respiratory depression, more rapid entry into the central nervous system, reduced sensitivity …

Few-Shot Learning For Ner Using Maml, Nourchene Bargaoui

Theses and Dissertations

This thesis investigates the application of Few-Shot Learning (FSL) using Model-Agnostic Meta-Learning (MAML) to enhance Named Entity Recognition (NER) within the domain of Natural Language Processing (NLP), specifically focusing on chemical datasets. The primary challenge addressed is the impracticality of relying on extensive annotated datasets, especially in specialized fields like chemistry. The research primarily explores the concept of Few-Shot Learning, aiming to train models on minimal data while maintaining performance across diverse tasks. It delves into the N-way K-shot methodology, where "N" represents the number of classes and "K" signifies the number of examples per class. This approach is further …

Haven: Exploring Trauma-Informed Design In Transitional Housing For Women And Children, Sydney J. Rakes

Theses and Dissertations

relevance

For 15 years, I have been a volunteer at a shelter for women and children. I interact with families and women who are suffering from the trauma caused by homelessness and domestic violence. In my observations, I have learned some spaces are more conducive to the staff and resident experiences than others. This project will be addressing how transitional housing for women and children can be designed to support the healing of trauma caused by domestic violence.

As of July 2023, there were about 150 women suffering from homelessness locally in the city of Richmond, Virginia (Homeward VA, 2023). …

Drugging The Histone Acetyltransferase Ep300 Modulates Alternative Splicing At Schizophrenia Risk Genes, Shravani Malay

Theses and Dissertations

Purpose. We will evaluate the effects of drugging the epigenetic histone acetyltransferase (HAT) enzyme p300, encoded by the schizophrenia risk gene EP300, on genome-wide gene expression in neural cells. We hypothesize that drugging p300 will affect gene expression and alternative splicing of other schizophrenia risk genes. Our motivation is to identify potential new epigenetic treatment avenues for schizophrenia.

Methods. Prior to my joining the lab, an experiment was conducted using the novel p300 HAT inhibitor, A-485, to modulate genomic regulation in a neural cell line (SH-SY5Y). SH-SY5Y cells were exposed to 10μM of A-485 or vehicle (DMSO) for 24 …

A Novel Dual Configuration Dart/Uhplc-Ms/Ms System For The Rapid Analysis Of Psilocybin-Containing Mushrooms And Other Seized-Drug Submissions, Aron R. Jaffe

Master of Science in Forensic Science Directed Research Projects

The use and availability of controlled substances is highly dynamic. When a classical or novel psychoactive substance becomes popular, an influx of seized-drug evidence submissions closely follows, contributing to an ever-growing backlog of exhibits awaiting identification. The need for inclusive, rapid, and robust analytical methods is apparent, as demonstrated by recent growth in hallucinogen use. Psilocybin and psilocin, among other entheogens, have become increasingly popular and an increase of psilocybin mushroom seizures by law enforcement has followed. The structural similarity and thermal lability of many entheogens preclude their identification using many conventional analysis techniques. A DART and UHPLC were interchangeably …